Musculoskeletal Herbs Flashcards
3 salicylate-containing anti-inflammatory analgesics
salix spp
filipendula ulmaria
actea racemosa
5 non-salicylate anti-inflammatories?
curcuma longa boswellia serrata zingiber officinale rosmarinus officinale tanacetum parthenium
4 topical analgesics?
capscium annuum
arnica spp
gaultheria procumbens EO
mentha EO
3 antispasmodics
valeriana officinalis
stachys betonica
viburnum opulus
2 sources of anti-inflammatory proteolytic enzymes?
ananas cosmosus
carica papaya
family: salicaceae
part used: bark
energetics: cooling, drying
constituents: salicyl glycosides - namely salicin –> convereted to salicylic acid by GI flora, flavonoids, other phenolics and tannins
salix spp (willow)
actions: anti-inflammatory, analgesic, febrifuge, astringent
indications: muscle and joint pain, H/As, fever
C/I: allergy to salicylates, G6PD deficiency, caution w/blood thinners
salix spp (willow)
delivers salicylic acid into the bloodstream via salicin is first carried unchanged into the distal ileum or colon where gut flora remove the sugar and convert it to salicyl alcohol, this is then absorbed and oxidized in the blood, tissue and liver to salicylic acid
how the salicin in salix spp works
salicylic acid’s effects on platelets?
little anti-platelet effect because it lacks an acetyl group that aspirin has
family: roseaceae
part used: aerial parts
energetics: cooling and drying
constituents: volatile oils- salicylaldehyde, methyl salicylate, phenolic glycosides, flavonoids; spiraeoside; tannins, small amount of salicyles
filipendula ulmaria (meadowsweet)
actions: anti-inflammatory, diaphoretic, diuretic, antibacterial
indications: burning pains, gastritis, peptic ulcers
C/I: salicylate allergy
filipendula ulmaria (meadowsweet)
family: ranunculaceae
part used: root and rhizome
constituents: triterpene glycosides, isoferulic acid, salicylic acid, volatile oils and tannins
actaea racemosa (cimicifuga racemosa)
actions: antispasmodic, anti-inflammatory, anti-rheumatic, alterative, nervine, hypotensive; sometimes referred to as “estrogenic” b/c it is therapeutic in conditions associated with low E levels
actaea racemosa (cimicifuga racemosa)
specific indications and uses: muscular pains, uterine pains, with tenderness; false pains, irregular pains; rheumatism of the uterus; dysmenorrhea, anti-rheumatic when pulse is open, pain is paroxysmal, skin not dry and constricted, dragging pains in the hips and loin, rheumatoid muscular pain, rheumatoid dyspepsia, chorea, associated w/absentio mensium
actea racemosa (cimicifuga racemosa)
family: asteraceae part used: leaf and flower constituents: sesquiterpene lactones- parthenolide, volatile oils, bioflavonoids preparations infusion: 1 tsp of herb/c water tincture: 10-30 drops TID SE: 50-150 mg daily for migraine prophylaxis, 100-300 up to QID for migraine tx CO2 extract: 6.25 mg TID traditional use: 1-3 fresh leaves
tanacetum parthenium (feverfew)
actions: antimicrobial, anti-inflammatory, febrifuge, reduces secretion of inflammatory mediators from WBCs and platelets, inhibits prostaglandin synthesis, vascular stabilizer; prevents dilation and contraction, inhibits release of histamine from mast cells
specific indications: specific for migraine H/A w/ internal heat, used for RA and inflammation, used in febrile illness
tanacetum parthenium (feverfew)
family: zingiberaceae
part used: rhizome
energetics: cooling, warming, stimulating, moves stagnation
constituents: curcumin, volatile oil, mainly composed of tumerone, atlantone and zingiberone; resin; disaccharides; protein, vitamins and minerals
curcuma longa (tumeric)
actions: alterative, anti-inflammatory, antioxidant, anticarcinogenic, cholagogue, choleretic, emmenagogue, lowers cholesterol, carminative, hepatoprotective, cardioprotective, vulnerary
specificity of seat: liver, circulatory system
indications: inflammation of all kinds, jaundice, liver d/os, chronic skin conditions, CVD
C/I: lg doses in PG, bile duct obstruction
curcuma longa (turmeric)
summary of properties of curcumin?
diarylheptanoid- has a keto and enol form, bright yellow/orange in color, highly conjugated
poor bioavailability- poor solubility in water, more soluble in oil
rapid metabolism