Musculoskeletal Development Flashcards

1
Q

What does gastrulation do

A

produces the ectoderm, mesoderm, endoderm, and notochord

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2
Q

what is the ectoderm

A

epidermis and nervous system

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3
Q

what is the mesoderm

A

msuscle, bone, blood, urogenital

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4
Q

what is the endoderm

A

epithelial lining of gut

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5
Q

what is the notochord

A

central support structure

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6
Q

three sections of the mesoderm

A

paraxial mesoderm, intermediate mesoderm, lateral plate mesoderm

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7
Q

what does the paraxial mesoderm produce

A

vertebrae, postcranial voluntary musculature, dermis

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8
Q

what does the intermediate mesoderm produce

A

urogenital system

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9
Q

what does the lateral plate mesoderm produce

A

appendicular skeleton and smooth muscle of gut

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10
Q

what does the paraxial mesoderm specialize into

A

segmentally arranged somites

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11
Q

whare does segmental arrangement of somites mean

A

somites are paired structures with one one either side of the notochord and are assicdiated with a specific spinal level and nerve

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12
Q

what does spinal level segmentation mean

A

what happens tot he somite happens to all structures associates with the somite

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13
Q

somites are divided into what primary structures

A

sclerotome and dermomyotome

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14
Q

what is the sclerotome destined to become

A

vertebrae

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15
Q

what is the dermomyotome destined to become

A

structures establishing the motor and sensory patters associated with the spinal cord

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16
Q

What are the parts of the dermomyotome

A

dermotome and myotome

17
Q

describe the dermatome

A

becomes the dermis of the skin and establishes pattern association between skin sensation and spinal cord

18
Q

describe the myotome

A

becomes voluntary musculature and establishes pattern association between muscle function and spinal cord

19
Q

what are the two primary structures of myotomes

A

epimere and hypomere

20
Q

what does the epimere become

A

the epaxial muscles assiciated with dorsal ramus of mixed spinal nerve

21
Q

what does the hypomere become

A

the hypaxial muscles associated with the ventral ramus of the mixed spinal cord

22
Q

when does upper limb development begin

A

day 24

23
Q

when does lower limb development begin

A

day 26

24
Q

when is limb development mostly completed

A

day 60

25
Q

how do limbs form

A

emerge as bud off the parietal layer of the lateral plate mesoderm

26
Q

upper limb myotomes

A

C5-T1

27
Q

lower limb myotomes

A

L2-S3

28
Q

upper limb dermatomes

A

C5-T1

29
Q

lower limb dermatomes

A

L2-S3