Musculoskeletal and trauma Flashcards
1
Q
- A 17 year old girl presents with pain in the distal forearm which has worsened over
the last six to eight weeks. Plain films show an eccentric lytic radiolucency in the distal
radius with a soap-bubble appearance. The most likely pathology is:
a. Enchondroma
b. Aneurysmal bone cyst
c. Simple bone cyst
d. Fibrous dysplasia
e. Chondroblastoma
A
- b. Aneurysmal bone cyst
Aneurysmal bone cyst is most common in females and 75% occur under 20 years of age.
The classic presentation is of pain of relatively acute onset with a rapid increase in severity
over 6–12 weeks. Common locations include the spine, with a slight preponderance for the
posterior elements, and the metaphysis of long bones – femur, tibia, humerus and fibula.
The lesion is usually expansile with thin internal trabeculations giving it the characteristic
soap-bubble appearance.
2
Q
- A 35 year old man presents with increasing stiffness in his knee and soft-tissue swelling
around the joint. Plain films show multiple areas of irregular cyst-like radiolucencies
in the distal femur. There are no areas of abnormal calcification and there is no evidence
of periarticular osteoporosis. MR shows a low signal joint effusion on both T1 and T2
sequences. The most likely diagnosis is:
a. Synovial osteochondromatosis
b. Pigmented villonodular synovitis
c. Osteoarthritis
d. Reiter’s syndrome
e. Osteomyelitis
A
- b. Pigmented villonodular synovitis
Pigmented villonodular synovitis is a relatively rare condition which usually presents in the
third or fourth decade. It is a monoarticular, painful disease which causes a decreased range
of movement at the affected joint. It is most common at the knee (80%) followed by the hip,
ankle, shoulder and elbow. Haemorrhagic ‘chocolate’ effusion is characteristic. Low signal
effusion on all sequences at MR is characteristic. There is no calcification or osteoporosis,
and joint space narrowing is a late feature.
3
Q
- A 56 year old motorcyclist has a trauma series of plain films following a road traffic
accident. On evaluation of the lateral cervical spine film, which of the following softtissue
parameters would be a concerning feature?
a. Predental space of 3mm
b. Nasopharyngeal space of 7mm
c. Retropharyngeal space of 10mm
d. Retrotracheal space of 20mm
e. Decreased disc space at the C5/6 level
A
- c. Retropharyngeal space of 10mm
This is too wide for the retropharyngeal space. The correct acceptable limits for soft-tissue
measurements are as follows:
Predental space 3mm in adults, 5mm in children.
Nasopharyngeal space (anterior to C1) 10 mm.
Retropharyngeal space (C2–C4) 5–7 mm.
Retrotracheal space (C5–C7) 22 mm.
Disc spaces should be roughly equal throughout the cervical spine. Narrowing of a disc
space is usually due to degenerative change, but widening would be a more concerning
feature.
4
Q
- A 20 year old man presents with an increasingly painful right thigh which is worse at
night. Plain films of the area show a lucent area measuring approximately 8–9mm in
the distal femur surrounded by extensive sclerosis. The most likely diagnosis is:
a. Osteoblastoma
b. Giant cell tumour
c. Brodie’s abscess
d. Osteoid osteoma
e. Chondroblastoma
A
- d. Osteoid osteoma
This most commonly presents in the second and third decades. The male:female ratio is
2.5:1. Classically it presents with increasing pain which is worse at night and often relieved
with aspirin. Spinal lesions often lead to painful scoliosis. Almost any site in the body may
be affected but the most common regions are the lower limb and spine.
5
Q
- In a 65 year old woman with a fracture of the neck of the humerus, which of the
following classification systems to describe the fracture would be useful in guiding the
surgical management?
a. Garden classification
b. Neer classification
c. Weber classification
d. Fryman system
e. Crosby–Fitzgibbon system
A
- b. Neer classification
The Neer classification system is used to grade humeral neck fractures. This system
describes four parts – greater tuberosity, lesser tuberosity, humeral head and shaft of
humerus. According to Neer, a fracture is displaced if there is more than 1 cm of displacement
and 45 angulation between any two segments. Two-part fractures involve any of the
four parts and include one fragment that is displaced. Three-part fractures include a
displaced fracture of the surgical neck in addition to either a displaced greater tuberosity
or lesser tuberosity fracture. Four-part fractures include displaced fractures of the surgical
neck and both tuberosities.
6
Q
- A 60 year old woman presents to her GP with renal colic and hypercalcaemia. She has
the following findings on plain film: subperiosteal bone resorption of the proximal
phalanges of the hands, chondrocalcinosis of the articular cartilage at the knee joints,
and a well-defined lytic lesion in the body of the mandible. The most likely unifying
diagnosis is:
a. Parathyroid adenoma
b. Parathyroid carcinoma
c. Renal osteodystrophy
d. Osteomalacia
e. Myeloma
A
- a. Parathyroid adenoma
Parathyroid adenoma would be the most likely cause of primary hyperparathyroidism.
Parathyroid carcinoma would produce a similar radiographic picture but is much less
common. Brown tumours are seen in both primary and secondary hyperparathyroidism
and are most common in the mandible, ribs and pelvis; they have a variable appearance on
MRI and may simulate primary or secondary neoplasms
7
Q
- In a 21 year old man with symptoms of chronic back pain, pain in his feet, particularly
the great toe and metatarsophalangeal joints, and bilateral sacroiliitis on plain films, the
most likely diagnosis is:
a. Ankylosing spondylitis
b. Gout
c. Inflammatory bowel disease-related arthropathy
d. Reiter’s syndrome
e. Psoriatic arthritis
A
- d. Reiter’s syndrome
Reiter’s syndrome is the association of urethritis, conjunctivitis and mucocutaneous
lesions. Sacroiliitis is usually bilateral but often persists asymmetrically. There is an
association with the HLA B27 antigen. Reiter’s has a predeliction for the great toe and
metatarsophalangeal joints.
8
Q
- A 45 year old woman falls onto her outstretched hand. The following findings on PA
and lateral wrist plain films indicate which pathology? A scapholunate angle of 70,
a capitolunate angle of less than 20, and a 4mm gap between scaphoid and lunate
on PA view.
a. Normal appearances
b. Scapholunate dissociation
c. Volar intercalated segment instability (VISI)
d. Dorsal intercalated segment instability (DISI)
e. Perilunate dislocation
A
- b. Scapholunate dissociation
In scapholunate dissociation the scapholunate angle is >60 and there is a >3mm gap
between the scaphoid and lunate on AP view of the wrist. In VISI, capitolunate angle is
increased and there is volar angulation of the lunate. In DISI, both scapholunate and
capitolunate angles are increased and there is dorsal angulation of the lunate.
9
Q
- A young man presents to A&E following a fall onto his outstretched right arm. Plain
films of the right forearm show a fracture of the distal forearm with volar angulation
of the distal fragment with no intra-articular component. The carpal bones remain
well aligned. Which of the following injuries has he sustained?
a. Smith’s fracture
b. Barton’s fracture
c. Monteggia fracture
d. Galeazzi fracture
e. Colles fracture
A
- a. Smith’s fracture
This description is of a Smith’s fracture. More common is a Colles fracture, which is
a fracture of the distal radius with dorsal angulation of the distal fragment. A Monteggia
fracture is fracture of the ulnar with dislocation of the radial head. A Galeazzi fracture is
a fracture of the radius with dislocation of the distal ulnar. Barton’s fracture is a fracture of
the distal radius with dislocation of the distal radiocarpal joint
10
Q
- A 24 year old man injured his left knee whilst skiing. He presents with pain and
swelling over the lateral aspect of the knee joint. AP plain radiographs demonstrate an
avulsion fracture of the lateral aspect of the proximal tibia below the articular surface.
A joint effusion is also seen. The most likely associated ligamentous injury is to which
of the following structures?
a. Posterior cruciate ligament
b. Anterior cruciate ligament
c. Medial collateral ligament
d. Lateral collateral ligament
e. Ligament of Humphry
A
- b. Anterior cruciate ligament
The fracture described is a Segond fracture, originally documented by Dr Paul Segond in
1879 after a series of cadaveric experiments. The Segond fracture occurs most commonly
in association with anterior cruciate ligament injuries (75–100%) and medial meniscal
injuries. Due to the high rate of associated injuries, a patient who sustains a Segond fracture will require further imaging, usually by way of MRI, in order to specifically investigate the
ligaments and menisci.
11
Q
- A 22 year old man presents to his GP with pain in his right knee which is gradually
worsening in severity and is relatively resistant to analgesia. MRI of the knee demonstrates
an area of geographic bone destruction in the distal femur with a wide zone of
transition. There is marked aneurysmal dilatation of the bone and a fluid-fluid level is
present within the lesion. The most likely diagnosis is:
a. Plasmacytoma
b. Simple bone cyst
c. Giant cell tumour
d. Telangiectatic osteosarcoma
e. Parosteal osteosarcoma
A
- d. Telangiectatic osteosarcoma
With the MRI finding described, the most likely explanation is that the lesion is a
telangiectatic osteosarcoma. This is a rare type of osteosarcoma with a mean age at
presentation of 20 years. The most common site is around the knee (62%). Fluid-fluid
levels are also seen in giant cell tumours and aneurysmal bone cysts.
12
Q
- A 32 year old footballer sustains an avulsion injury to the anterior superior iliac spine
during training. Which of the following muscles is likely to be affected?
a. Sartorius
b. Gracilis
c. Iliopsoas
d. Rectus femoris
e. Semimembranosus
A
- a. Sartorius
Sartorius has its origin at the anterior superior iliac spine and inserts into the pes anserinus.
A sartorius muscle injury can therefore cause an avulsion fracture of the anterior superior
iliac spine. Gracilis has its origin at the inferior pubic ramus, and rectus femoris has its
origin at the anterior inferior iliac spine
13
Q
- A middle-aged woman undergoes an MRI of the lumbar spine for longstanding lower
back pain. She has no specific neurological signs and is otherwise well. MRI shows
some lower lumbar spine facet joint arthropathy and a 22 cm well-defined rounded
lesion in the L3 vertebral body. This displays high signal on both the T1 and T2
sequences. The most likely explanation for this lesion is:
a. Discitis
b. Lymphoma
c. Myeloma
d. Metastatic deposit
e. Haemangioma
A
- e. Haemangioma
This is most likely to be a benign haemangioma. These are relatively common lesions seen as
incidental findings on spinal imaging. High signal on T1 imaging is indicative of the presence
of fat within the lesion. All the other conditions would give a low-signal lesion on T1 imaging.
14
Q
- A 21 year old long-distance runner complains of increasing right groin pain.
Plain films show no acute bony injury, but demonstrate a pistol grip deformity
of the femoral head, an osseous bump deforming the femoral head–neck junction
and an alpha angle of 70. The acetabulum appears normal. The most likely
diagnosis is:
a. Hip dysplasia
b. Pincer-type acetabular impingement
c. Cam-type acetabular impingement
d. Sportsman’s hernia
e. Avascular necrosis
A
- c. Cam-type acetabular impingement
Femoroacetabular impingement (FAI) occurs as a result of repetitive microtrauma due to
an anatomic conflict between the proximal femur and the acetabular rim at the extremes of
motion. An osseous bump at the femoral head–neck junction is present in 50% of cam-type
FAI and only 33% of pincer-type FAI. An alpha angle of >55 is indicative of cam-type FAI.
The alpha angle, drawn on the AP pelvis radiograph, is formed by a line drawn from
the centre of the femoral head through the centre of the femoral neck, and a line from the
centre of the femoral head to the femoral head–neck junction, found by the point by which
the femoral neck diverges from a circle drawn around the femoral head. A normal patient’s
alpha angle is around 45, whereas for patients with FAI it may be around 70.
15
Q
- A 24 year old rugby player attends A&E following a tackle during which he felt his left
shoulder dislocate. Initial plain radiographs confirm an anterior inferior dislocation
of the left shoulder. Which of the following statements is true?
a. The humeral head lies inferior and lateral to the glenoid on the AP view
b. The presence of a Hill–Sachs defect indicates previous dislocation
c. Hill–Sachs lesions are more common than Bankart lesions
d. Anterior dislocation accounts for 50% of shoulder dislocations
e. A Hill–Sachs lesion affects the inferior aspect of the humeral head
A
- c. Hill–Sachs lesions are more common than Bankart lesions
A Hill–Sachs lesion affects the postero-superior aspect of the humeral head and whilst it
does often indicate a previous dislocation, this is not necessarily the case and it can be
present after a single episode. A Bankart lesion affects the inferior glenoid. Almost 95% of
all shoulder dislocations are anterior.
16
Q
- In a 26 year old woman with sickle cell disease, which one of the following would not
be considered a typical musculoskeletal manifestation of the disease?
a. Osteopaenia and trabecular thinning
b. ‘Bone within bone’ appearance
c. Avascular necrosis of the femoral head
d. Posterior vertebral scalloping
e. Fish deformity of the vertebrae
A
- d. Posterior vertebral scalloping
Posterior vertebral scalloping is not a feature. The remainder are all classic features of sickle
cell anaemia, along with ‘hair-on-end’ appearance of the skull due to coarse granular osteoporosis and widening of the diploe. Osteomyelitis is a feature and is due to salmonella in over 50% of cases.
17
Q
- A 74 year old woman presents with back pain and no history of recent trauma.
Lateral plain radiographs show partial collapse of the L2 vertebral body. Which of
the following findings would be more suggestive of osteoporotic collapse than
malignancy?
a. Complete replacement of the normal marrow signal within the vertebral body
on T1 imaging
b. Bilateral pedicular involvement with expansion of the right pedicle
c. Bulging and convex appearance to the vertebral body
d. Nodular irregular epidural mass
e. Intervertebral vacuum phenomenon
A
- e. Intervertebral vacuum phenomenon
Intervertebral vacuum phenomenon is highly specific for osteoporotic collapse, although it
is not common. The other features are all more suggestive of malignancy than osteoporotic
collapse. Pedicular destruction occurs in 50% of cases of malignant collapse but in less than
1% of osteoporotic collapse.
18
Q
- A 23 year old man sustains a Jefferson fracture to his cervical spine following an injury
in which he dived into a shallow swimming pool, hitting his head on the bottom.
Which of the following regarding his injury is incorrect?
a. Displacement of the lateral masses of C1 relative to the dens on an odontoid view
indicates a transverse ligament rupture
b. Associated C2 fracture will be present in up to 30% of cases
c. Jefferson fractures are usually associated with a neurological deficit
d. Up to 50% are associated with a further cervical spine injury
e. There may be associated vertebral artery injury
A
- c. Jefferson fractures are usually associated with a neurological deficit
Jefferson fractures are not usually associated with neurological deficit. Although there may
be retropulsion of fragments into the vertebral canal, spinal cord injury is rare due to the
large dimensions of the canal at this level. Vertebral artery injury, however, must be
considered and if there is concern either CTA or MRA imaging should be considered.
19
Q
- A 50 year old woman presents with a mass on the plantar aspect of her right foot.
Ultrasound reveals a small oval-shaped lesion between the plantar portions of the
metatarsal heads. MRI characteristics of the lesion are low-to-intermediate signal
on T1 and low signal intensity on T2. Which of the following is the most likely
diagnosis?
a. Lipoma
b. Morton’s neuroma
c. Plantar fibromatosis
d. Giant cell tumour of the tendon sheath
e. Ganglion cyst
A
- b. Morton’s neuroma
The description is that of a Morton’s neuroma. This occurs most commonly in the third
metatarsal space and less commonly in the second space. There is often an associated
metatarsal bursitis which is a high signal on STIR imaging. Ultrasound is usually the first
imaging modality; squeezing the metatarsal heads together during scanning will usually
make the lesion more prominent.
20
Q
- Following a traumatic left elbow fracture, a young man complains of paraesthesia in
his left ring and little fingers. He also starts to notice weakness of his left hand.
A diagnosis of ulnar nerve entrapment is made. Which of the following muscles will
not be affected?
a. Abductor digiti minimi
b. Abductor pollicis brevis
c. Adductor pollicis
d. Flexor carpi ulnaris
e. Flexor digiti minimi
A
- b. Abductor pollicis brevis
Abductor pollicis brevis is supplied by the median nerve and would therefore not be affected
in an ulnar nerve injury. Due to the anatomic location of the ulnar nerve at the elbow, it can
often be damaged leading to denervation and paralysis of the muscles supplied by the nerve.
This includes the intrinsic muscles of the hand, which can be very debilitating. Injury to the
ulnar nerve at the wrist would lead to severe muscle denervation sparing only the opponens
pollicis, the superficial head of the flexor pollicis brevis and the lateral two lumbricals
21
Q
- A routine pre-operative chest X-ray in a 62 year old woman shows bilateral erosion of
the distal clavicles. Which one of the following conditions might be responsible?
a. Hypoparathyroidism
b. Rheumatoid arthritis
c. Langerhans’ cell histiocytosis
d. Ankylosing spondylitis
e. Sarcoidosis
A
- b. Rheumatoid arthritis
Myeloma, hyperparathyroidism, metastases, cleidocranial dysplasia and Gorlin basal cell
nevus syndrome all cause absence of the outer end of the clavicle. Destruction of the medial
end of the clavicle is caused by metastases, infection, lymphoma, eosinophilic granuloma,
rheumatoid arthritis and sarc
22
Q
- A 74 year old woman with back pain presents to her GP. Initial plain radiographs of
her spine show multiple sclerotic metastatic lesions. The most likely primary tumour
would be:
a. Renal cell carcinoma
b. Melanoma
c. Bronchial carcinoid
d. Bladder
e. Colorectal carcinoma
A
- c. Bronchial carcinoid
The most likely from the above list is a bronchial carcinoid. In men the most likely cause
would be prostate. All the other conditions are more likely to produce lytic metastases
than sclerotic.
23
Q
- An elderly gentleman complaining of generalised aching in his lower limbs is shown to
have bilateral distal tibial periostitis. There is no underlying bone lesion identified.
Which of the following would be the most likely explanation?
a. Arterial insufficiency
b. Thyroid acropachy
c. Trauma
d. Pachydermoperiostosis
e. Hypertrophic pulmonary osteoarthropathy
A
- e. Hypertrophic pulmonary osteoarthropathy
The most likely explanation is hypertrophic osteoarthropathy. Thyroid acropachy changes
usually occur in the upper limb. Venous stasis is a cause of periostitis rather than arterial
insufficiency. Trauma would be unlikely to be bilateral unless there was a specific history.
Pachydermoperiostitis is the idiopathic form of hypertrophic osteoarthropathy, it usually
presents around adolescence and is usually associated with clubbing.
24
Q
- A 28 year old man is brought into the emergency department following an assault during
which he was stabbed in the left flank. He has a 1.3 cm wound just below the left costal
margin in the mid-axillary line. No information regarding the knife has been obtained.
His renal function is within normal limits and he has no contrast allergies. The optimal CT
protocol for scanning his abdomen would include the following contrast:
a. IV contrast only
b. Oral contrast and rectal contrast
c. IV contrast and oral contrast
d. Oral, rectal and IV contrast
e. IV contrast and rectal contrast
A
- d. Oral, rectal and IV contrast
A triple contrast technique has been advocated in penetrating trauma where there may be
concern regarding small bowel or colon trauma. If no oral or rectal contrast are given then
a small bowel or colon injury can easily be missed.
25
25. A 75 year old man who is on warfarin for atrial fibrillation is involved in a high-speed
road traffic accident in which he sustains a head injury. He lost consciousness at the
scene. On arrival at the A&E department his GCS is 15. He has no other obvious
injuries. According to NICE guidelines, his management should include the following:
a. Skull radiograph
b. No immediate imaging but admission for regular neurological observations
c. CT head
d. Skull radiograph followed by CT head
e. MRI head
25. c. CT head
According to NICE guidance he should undergo CT head and the investigation should be
performed within the hour following referral. The fact he is anticoagulated, over 65 and
experienced a loss of consciousness would all be factors in warranting an urgent CT head.
26
26. A young man with limited range of movement at the shoulder joint, a webbed neck and
plain film findings of a hypoplastic scapula which is elevated and medially rotated
with an associated omovertebral bone is likely to have which associated syndrome?
a. Turner’s syndrome
b. Down’s syndrome
c. Klippel–Feil syndrome
d. Neurofibromatosis
e. Cleidocranial dysostosis
26. c. Klippel–Feil syndrome
The collective findings described are of a Sprengel deformity of the shoulder. This occurs
as a result of failure of descent of the scapula secondary leading to both cosmetic and
functional impairment. The male:female ratio is 3:1 and it is associated with Klippel–Feil
syndrome, a condition in which there is fusion of vertebral bodies, and renal anomalies
27
27. A 52 year old woman presents to her GP with a longstanding history of lower back pain
which has suddenly worsened in severity over the past few days. An urgent MRI scan of
the lumbar spine shows a right paracentral disc protrusion at the L4/L5 level. The disc
impinges on the lateral recess at this level. The most likely nerve to be affected is the:
a. Cauda equina
b. Lumbar plexus
c. Right L4
d. Right L5
e. Right S1
27. d. Right L5
The right L5 nerve root is the most likely to be affected as it will be sitting in the right lateral
recess at the L4/5 level. The L4 nerve root will be at the exit foramen and therefore if the
protrusion affects only the lateral recess then this nerve will already have exited and
therefore not be affected
28
28. An 18 year old student who fell down two stairs and landed on her left knee attends
A&E complaining of generalised knee pain but is able to weight bear. No acute bony
injury is demonstrated on plain film, however a pedunculated lesion arising from the
femoral metaphysis and extending away from the knee joint is seen. The lesion
shows continuity with both the marrow and the cortex. The most likely diagnosis is:
a. Osteochondroma
b. Osteoblastoma
c. Osteoid osteoma
d. Chondroblastoma
e. Chondromyxoid fibroma
28. a. Osteochondroma
The description is classic for an osteochondroma or osteocartilagenous exostosis. These
lesions are the most common benign growths of the skeleton, are usually found incidentally
and are usually asymptomatic unless complications arise. Complications include
fracture, vascular compromise, bursa formation and malignant transformation into
chondrosarcoma.
29
29. A 70 year old male presents with increasing pain in his right hip over the past month.
There is no specific history of trauma. A plain radiograph demonstrates the presence
of an incomplete fracture of the femoral neck arising from the lateral (convex) side.
What is the most likely underlying abnormality of the femoral neck?
a. Osteomalacia
b. Metastasis
c. Osteoid osteoma
d. Infection
e. Paget’s disease
29. e. Paget’s disease
Incremental fractures (banana fracture) along the convex side of the bone are classically
associated with Paget’s disease. These most commonly occur in the femur where they cause
lateral bowing, and the tibia where they cause anterior bowing. Compression fractures of
the vertebrae are also associated with Paget’s
30
30. A 75 year old woman presents with increasing pain in her left hip. She had a total hip
replacement eight years ago on this side which has been asymptomatic ever since. Plain
radiographs demonstrate a lucent line at the bone cement interface of the femoral
component. The likely cause for this is:
a. Infection
b. Metastasis
c. Loosening
d. Myeloma
e. Trauma
30. c. Loosening
Early changes (less than six months) are almost always due to infection. Up to four years,
infection remains the most likely cause, but after this point loosening becomes more
common. Every year, 38 000 hips are replaced in the UK. A routine postoperative film is
usually performed; an excessively varus stem may lead to loosening.
31
31. A 17 year old patient complains of lower thoracic back pain. Plain radiographs of the
thoraco-lumbar spine show wedging of multiple vertebrae at the thoraco-lumbar
junction, multiple limbus vertebrae, an increase in the AP diameter with a reduction
in the sagittal height of multiple vertebrae, and multiple endplate defects. What is the
unifying diagnosis?
a. Scheuermann’s disease
b. Ankylosing spondylitis
c. Mycobacterium tuberculosis
d. Hyperparathyroidism
e. DISH
31. a. Scheuermann’s disease
These are the classical appearances of Scheuermann’s disease. This condition usually
presents at puberty and consists of vertebral wedging, endplate irregularity and narrowing
of the intervertebral disc spaces. The most common location is in the lower thoracic and
upper lumbar spine. Schmorl’s nodes are often present.
32
32. A 70 year old patient complains of back pain and leg pain after walking 50 metres.
Plain radiographs show an anterior slip of L4 relative to L5. The spinous process of
L4 is also noted to have moved anterior to the L5 spinous process. What type of
spondylolisthesis does this represent?
a. Traumatic
b. Degenerative
c. Spondylolytic
d. Dysplastic
e. Pathological
32. b. Degenerative
This is the classical description of the symptoms and radiology of a degenerative spondylolisthesis.
Degenerative spondylolisthesis is usually symptomatic due to spinal stenosis and
narrowing of neural foramen. This most commonly occurs at the L4/5 level. Spondylolisis
is a defect in the pars interarticularis between superior and inferior articulating processes
33
33. A 56 year old male is admitted under the orthopaedic team with increasingly severe
lower back pain which started three weeks ago. MRI demonstrates an oedematous L4/5
intervertebral disc, marked loss of disc material and oedematous adjacent endplate
changes. There is associated paravertebral inflammatory tissue and a small amount of
pus within the residual disc space. The findings are consistent with infective discitis.
What is the most likely causative organism?
a. Mycobacterium tuberculosis
b. Streptococcus pyogenes
c. Staphylococcus aureus
d. Escherichia coli
e. Salmonella
33. c. Staphylococcus aureus
The most common cause of infective discitis is Staphylococcus aureus, which gives the above
typical findings. The only other relatively common cause is Mycobacterium tuberculosis,
which typically spares the disc until late and usually has a large amount of associated pus
34
34. A 25 year old male is involved in a 60 mph road traffic accident with a head-on
collision. He was wearing a seat-belt but his car did not have an air-bag.
A screening lateral radiograph of the cervical spine shows the following findings:
an angular kyphosis centred at C4/C5, a 1mm anterior slip of C4 on C5, and
widening of the interspinous space posteriorly. What is the likely mechanism for this
injury?
a. Lateral compression
b. Flexion
c. Extension
d. Combination
e. Rotation
34. b. Flexion
This describes the typical appearance for a flexion injury as well as the typical mechanism.
This would represent a potentially unstable fracture and immobilisation would be essential
until further management decisions are made. Flexion teardrop injuries are more common
in the lower cervical spine and extension teardrop injuries are more common in the upper
cervical spine.
35
35. A young man presents to his GP complaining of longstanding back pain. He says he
has been diagnosed with a ‘syndrome’ in the past but cannot remember the details.
Which of the following signs is more likely to suggest a diagnosis of homocystinura
than Marfan’s syndrome?
a. Arachnodactyly
b. Osteoporosis
c. Scoliosis of the spine
d. Autosomal dominant inheritance
e. Upward lens dislocation
35. b. Osteoporosis
Osteoporosis is a feature of homocystinuria and occurs in 75% of cases, often causing
bowing and fracture of the long bones. The other features are all more suggestive
of Marfan’s syndrome. Although arachnodactyly does occur in homocystinuria (in 30% of cases), it occurs in 100% of people with Marfan’s syndrome. Homocystinuria has an
autosomal recessive mode of inheritance.
36
36. A 56 year old woman slips off the pavement onto the road and her outstretched foot is
run over by a passing car. She has immediate severe midfoot pain. Plain radiographs
taken on arrival at the emergency department confirm a Lisfranc fracture dislocation of
the midfoot. Which two bones does the Lisfranc ligament attach to?
a. First metatarsal and intermediate cuneiform
b. First metatarsal and medial cuneiform
c. Second metatarsal and medial cuneiform
d. Second metatarsal and intermediate cuneiform
e. First and second metatarsals to the medial and intermediate cuneiforms
36. c. Second metatarsal and medial cuneiform
The Lisfranc ligament attaches between the second metatarsal and medial cuneiform, which
is why an injury to this ligament allows the second to fifth metatarsals to drift laterally once
they have lost this stabilisation. This is therefore an unstable injury and requires rapid
immobilisation. This is a vital injury to detect as long-term sequelae will often result from a
delayed diagnosis.
37
37. A 24 year old man suffers a short oblique fracture of his distal tibia from a direct blow
during a football game. He is treated with an intramedullary nail with a good reduction
being achieved. Fourteen days later the foot becomes very tender, red and swollen
but all haematological and biochemical parameters remain normal. Plain radiographs
show spotty osteoporosis and subchondral erosions. Which of the following is the most
likely diagnosis?
a. Disuse osteoporosis
b. Charcot joints
c. Infection
d. Regional sympathetic dystrophy
e. Rheumatoid arthritis
37. d. Regional sympathetic dystrophy
This is the typical appearance, history and imaging findings for regional sympathetic
dystrophy. This may occur following fractures or secondary to other pathologies such as
primary or secondary bone tumours. There is overactivity of the sympathetic nervous
system causing pain, swelling and hyperaemia with excessive bone resorption. This is
usually in a periarticular distribution and may simulate other disease processes
38
38. A 25 year old woman attends A&E after falling onto her right hand. A plain film of her
hand is taken in order to exclude fracture. No bony injury is seen. On examination,
however, there is painless swelling of the right index finger which she says has been
present for a few weeks. Incidental note is made of a small central lesion within the
medullary cavity of the middle phalanx of the index finger. There is no cortical
breakthrough or periosteal reaction but there is bulbous expansion of the bone with
thinning of the cortex. The lesion contains dystrophic calcifications. This is most likely
to represent:
a. Giant cell tumour of the tendon sheath
b. Unicameral bone cyst
c. Brown tumour
d. Enchondroma
e. Epidermal inclusion cyst
38. d. Enchondroma
This lesion is most likely to be an enchondroma. This is a benign cartilaginous growth in
the medullary cavity and is usually asymptomatic. It most commonly occurs in the small
bones of the hands and wrist but may also occur in the proximal humerus and proximal
femur. Epidermoid inclusion cysts are usually in the distal phalangeal tuft and there is often
a history of trauma. A bone cyst would be unusual in the phalanges
39
39. A 72 year old woman presents to her GP with pain in her right shoulder which is worse
on movement. Plain films of the right shoulder show loss of subacromial space and
superior subluxation of the humeral head. She is referred for an ultrasound with a
suspected supraspinatus tear. Which is the best position of the arm for visualisation
of the free edge of the supraspinatous tendon?
a. Adduction and internal rotation
b. Abduction and internal rotation
c. Adduction and external rotation
d. Abduction and external rotation
e. Flexion and internal rotation
39. a. Adduction and internal rotation
The best position for visualising the supraspinatous tendon is with the patient’s arm in
adduction and internal rotation. Often the patient may be asked to place the back of their
hand onto their back, or alternatively asking them to simulate putting the hand into the
back pocket of their trousers. The most medial part of the tendon when imaged transversely
is the free edge – this is where the majority of supraspinatous tears occur.
40
40. A 57 year old man with increasing pain and stiffness in his hands and feet and
worsening back pain presents to his GP. Plain films of his hands show sclerosis of
the terminal phalanges and several ‘pencil-in-cup’ erosions. There is destruction of
the interphalangeal joint of his right great toe with exuberant periosteal reaction.
There is also erosion of the posterior margin of the calcaneus. The most likely
diagnosis is:
a. Reiter’s syndrome
b. Ankylosing spondylitis
c. Rheumatoid arthritis
d. Psoriatic arthritis
e. Osteoarthritis
40. d. Psoriatic arthritis
This is usually HLA B27 positive and is associated with skin and nail changes in the
majority of cases. The hands are often described as having sausage digits, and erosions
with ill-defined margins are characteristic. Sacroiliitis is often present and most often
bilateral. Within the axial skeleton, there is often large bulky vertically orientated soft-tissue
ossification giving a ‘floating’ osteophyte appearance
41
41. A 20 year old student complains of a six-week history of pain and tenderness in his
right thigh associated with a soft-tissue mass. There is no definite history of trauma.
CT of the region shows a mass in the right distal femur with well-defined mineralisation
at the periphery and a less distinct lucent centre. On plain film, there is faint
calcification within the lesion and a radiolucent zone separating the lesion from bone.
The most likely cause is:
a. Tumoural calcinosis
b. Osteomyelitis
c. Myositis ossificans
d. Parosteal sarcoma
e. Osteosarcoma
41. c. Myositis ossificans
Often there is no distinct history of trauma, although this is the most common cause.
It usually occurs in the large muscles of the extremities and in the early stages it can be
difficult to distinguish from soft-tissue sarcomas. It is, however, separate from bone, unlike
parosteal sarcoma and post-traumatic periostitis. This is a self-limiting condition, most
commonly occurring in young athletic adults, with resorption occurring in approximately
one year
42
42. A 60 year old man is referred for an MRI of his left upper leg after noticing a slowly
enlarging firm mass measuring approximately 7–8 cm in maximum diameter.
The mass is located in the quadriceps muscle group and is causing cortical erosion
of adjacent bone. There are poorly defined calcifications within it and MR shows a
poorly defined lesion which is isointense to muscle on T1-weighted imaging and
hyperintense on T2-weighted imaging. The most likely diagnosis is:
a. Malignant fibrous histiocytoma
b. Benign fibrous histiocytoma
c. Liposarcoma
d. Fibrosarcoma
e. Elastofibroma
42. a. Malignant fibrous histiocytoma
Soft-tissue malignant fibrous histiocytoma is the most common primary malignant softtissue
tumour of later adulthood. It is most commonly seen in the lower extremities. It has a
metastatic rate of 42% and most commonly metastasises to the lung. Osseous malignant
fibrous histiocytoma presents as a painful, tender, rapidly enlarging mass and most
commonly arises in the metaphysis of long bones.
43
43. A 27 year old man who attends A&E following an alleged assault is shown to have
a left-sided longitudinal temporal bone fracture. Which of the following is a correct
association?
a. Facial nerve palsy in 50% of cases
b. Incudostapedial joint dislocation
c. Sensorineural hearing loss
d. Ophthalmoplegia
e. Rhinorrhoea
43. b. Incudostapedial joint dislocation
Longitudinal fractures of the temporal bone are more common than transverse fractures
and account for over 85% of temporal bone fractures. They are associated with otorrhea,
conductive hearing loss, pneumocephalus, herniation of the temporal lobe and incudostapedial
dislocation. Transverse fractures are associated with sensorineural hearing loss, and a
higher percentage of facial nerve palsies
44
44. A 24 year old woman presents with a painless mass on the dorsal aspect of the right
index finger measuring approximately 11 cm. MRI shows a lobulated lesion which
has low signal intensity on both T1- and T2-weighted imaging. Which of the following
is the most likely diagnosis?
a. Haemangioma
b. Lipoma
c. Ganglion cyst
d. Giant cell tumour of the tendon sheath
e. Neurilemmoma
44. d. Giant cell tumour of the tendon sheath
This is a benign lesion thought to represent an extra-articular form of pigmented villonodular
hyperplasia. This is low signal on both T1- and T2-weighted imaging due to
haemosiderin deposition. It most commonly affects the fingers and characteristically lies
along a tendon sheath
45
45. A dental radiograph of a 47 year old woman shows loss of the lamina dura of the
majority of the teeth. Which of the following would be a possible cause?
a. Osteopetrosis
b. Hypoparathyroidism
c. Scleroderma
d. Sickle cell anaemia
e. Myeloma
45. c. Scleroderma
The other causes of loss of the lamina dura include Cushing’s disease, Paget’s, hyperparathyroidism,
osteoporosis, osteomalacia, leukaemia, metastases and Langerhans’ cell histiocytosis.
Both osteopetrosis and hypoparathyroidism cause thickening of the lamina dura of
the teeth.
46
46. A 28 year old long-distance runner is to undergo MR arthrography of the hip joint
for a suspected labral tear. Which of the following statements is correct regarding
MR arthrography?
a. A solution of 20mmol/L gadopentetate dimeglumine is injected into the hip joint
under fluoroscopic guidance
b. Patients with developmental dysplasia of the hip are at increased risk of labral tears
c. A communication between the joint capsule and the iliopsoas bursa is always
pathological
d. T2-weighted imaging is used to visualise the high signal of the gadopentetate
dimeglumine solution
e. The normal labrum has uniformly high signal on T1-weighted imaging
46. b. Patients with developmental dysplasia of the hip are at increased risk of labral
tears
The increased risk of labral tears in developmental dysplasia is due to the increased stress
placed upon the acetabular rim and labrum. A communication between the joint capsule
and iliopsoas bursa has been described as a normal finding in 10–15% of patients. A dilute
solution of 0.2mmol/L gadopentetate dimeglumine solution would usually be used for
arthrography. A normal labrum has uniformly low signal on T1-weighted imaging with slightly increased signal on gradient echo imaging. Appearances on T2-weighted imaging
can be more variable.
47
47. A 24 year old woman presents with worsening frontal headaches and a sixth nerve
palsy. A non-enhanced CT shows a lesion situated within the clivus with associated
bony destruction; there is soft-tissue extension into the nasopharynx. MRI shows a
large inter-osseous mass which is isointense to brain T1-weighted imaging and hyperintense
on T2. The most likely diagnosis is:
a. Sphenoid sinus cyst
b. Meningioma
c. Nasopharyngeal carcinoma
d. Metastasis
e. Spheno-occipital chordoma
47. e. Spheno-occipital chordoma
The most likely cause is a spheno-occipital chordoma. This is associated with bony
destruction in 90% of cases and is most usually within the clivus. Other sites include the
sella, petrous temporal bone, floor of middle cranial fossa and jugular fossa. Sacrococcygeal
chordoma is the most common subtype of chordoma and is usually located with the fourth
or fifth sacral segments. Vertebral/spinal chordoma accounts for only 15–20% of all
chordomas and is most often situated in the cervical spine.
48
48. Regarding scaphoid fractures, which of the following statements is correct?
a. 80% of scaphoid fractures occur at the waist
b. Approximately 5% of scaphoid fractures are complicated by avascular necrosis
c. Injury is typically due to hyperextension
d. Up to 60% of scaphoid fractures cannot be seen on initial radiograph
e. The specificity of CT in diagnosing scaphoid fractures is 60–70%
48. c. Injury is typically due to hyperextension
The scaphoid bone is the most commonly fractured carpal bone and the mechanism is
usually a fall onto the outstretched hand – ie. hyperextension of the wrist. The reported
sensitivities and specificities of CT are 89–97% and 85–100%, respectively. The high
negative predictive value of CT (96.8–99%) makes it very useful for ruling out a fracture.
Scaphoid fractures are missed on initial radiographs in up to 30% of cases.
(Ref: Kaewlai R et al. Multidetector CT of carpal injuries: anatomy, fractures, and fracturedislocations.
49
49. A 24 year old man is involved in a road traffic accident. On arrival in A&E he is
haemodynamically unstable and there is concern regarding pelvic fracture and associated
active extravasation. On multidetector CT, which of the following features is more
suggestive of pseudoaneurysm than active extravasation?
a. Ill-defined area of high attenaution on arterial phase imaging
b. Presence of a haemoperitoneum
c. Washout of the high-attenuation area on delayed imaging
d. Layering appearance on delayed imaging
e. Haemodynamically unstable patient
49. c. Washout of the high-attenuation area on delayed imaging
Washout of the high-attenuation area is one of the features of a pseudoaneurysm.
A pseudoaneurysm is likely to be adjacent to a vessel and whilst there will be a relatively
well-defined area of high attenuation on arterial phase imaging, this will diminish in
intensity on five-minute delayed imaging. In contrast to this, an area of active extravasation
will often appear as a jet of high attenuation which continues to collect and enlarge on
delayed phase imaging
50
50. A 27 year old woman is brought into A&E following a road traffic accident in which
she was knocked down by a car. On arrival she has a GCS of 15 but is haemodynamically
unstable and on examination she has abdominal bruising. The A&E consultant
has performed a FAST (focused assessment with sonography in trauma) scan in resus
and cannot see evidence of free fluid. What is the approximate minimal detectable fluid
volume by FAST scanning?
a. 10 ml
b. 50 ml
c. 100 ml
d. 200 ml
e. 500 ml
50. d. 200 ml
The approximate minimal detectable fluid volume is 200 ml. The distribution of free fluid
will be determined by both anatomical and physiologic factors and therefore the sensitivity
of the scan will depend upon the areas scanned. Ultrasound is often used in conjunction
with multidetector CT, particularly in the management of patients who have been involved
in trauma.
51
51. An A&E SHO has asked you to review a paediatric cervical spine plain film which has
been performed on a child who has been involved in a road traffic accident. He is
unsure as to whether or not the appearances are normal for a paediatric cervical spine
film. Which of the following findings is more likely to represent a true cervical spine
injury than a normal variant?
a. Absence of usual cervical lordosis
b. Widening of the prevertebral soft tissues in expiration
c. Increased distance between the tips of the C1 and C2 spinous processes in flexion
d. Wedging of the anterior aspect of the C3 vertebral body
e. A 7mm gap between the occipital condyles and the condylar surface of the atlas
51. e. A 7mm gap between the occipital condyles and the condylar surface of the atlas
This is highly suggestive of craniocervical injury; these injuries are often fatal and are often
caused by sudden deceleration. Radiologic evaluation of this injury can be difficult but is
crucial in determining further management. The remainder of the findings above can all be normal variants in the paediatric cervical spine and therefore should be interpreted
with care.
52
52. A 24 year old man has injured his right ankle playing football. The A&E SHO has
asked your opinion on the plain radiographs. These show a widening of the medial
joint space on the AP ankle view but no evidence of fracture, and an oblique fracture
of the proximal shaft of the fibula. This is the typical appearance for which of the
following fractures?
a. Weber B
b. Maisonneuve
c. Pilon
d. Dupuytren’s
e. Fibula stress fracture
52. b. Maisonneuve
This is the description of a Maisonneuve fracture (sometimes classified as Weber C3). This
injury is often overlooked as the patient may complain only of ankle pain and hence a full
tibia/fibula plain film is not taken. This fracture is often associated with ligamentous injury
at the ankle, most usually of the anterior talofibular ligament and the postero-inferior
talofibular ligament.
53
53. An 18 year old man undergoes a Tc MDP bone scan to investigate pain in the right hip.
A ‘hot’ lesion is seen in the right proximal femur. No other lesions are seen. Which
of the following lesions would appear as ‘hot’ on a Tc MDP bone scan?
a. Osteopoikilosis
b. Fibrous cortical defect
c. Acute fracture within 12 hours of injury
d. Fibrous dysplasia
e. Haemangioma
53. d. Fibrous dysplasia
The most common site of monostotic fibrous dysplasia is the ribs, followed by proximal
femur and craniofacial bones. Three-quarters of cases present before age 30. Other benign
lesions causing a ‘hot’ on bone scan include Paget’s disease, brown tumours, aneurysmal
bone cysts, osteoid osteoma and chondroblastoma.
Acute fractures are not usually ‘hot’ until after the first 24–48 hours.
54
54. A three month old boy presents with several small painful soft-tissue swellings which
have developed over the mandibular region and the right clavicle. Plain films show
marked periosteal new bone formation and localised soft-tissue swelling. There is also
bone expansion with remodelling of old cortex. The most likely diagnosis is:
a. Caffey disease
b. Hypervitaminosis A
c. Infantile myofibromatosis
d. Scurvy
e. Kinky hair syndrome
54. a. Caffey disease
The most likely diagnosis is Caffey disease. This is a relatively rare self-limiting condition
which usually presents before six months of age. The mandible is the most common site and
accounts for 80% of cases, followed by the clavicle and the upper limb bones.
55
55. A 29 year old woman presents with a painful right knee which has been worsening over
the previous few weeks. A plain film of the right knee shows an oval expansile lesion
with a radiolucent centre in the metaphyseal region of the proximal tibia. There is a
sclerotic margin and geographic bone destruction. There are internal septations and
stippled calcification. There is no periosteal reaction. The most likely diagnosis is:
a. Non-ossifying fibroma
b. Chondroblastoma
c. Giant cell tumour
d. Chondromyxoid fibroma
e. Chondrosarcoma
55. d. Chondromyxoid fibroma
This is most commonly seen in the second and third decades and the most common site is
the long bones, most often the proximal tibia and distal femur. Non-ossifying fibroma is
usually asymptomatic. The appearances of a chondroblastoma would be similar but this
would most likely be epiphyseal in location and usually presents in a slightly younger age
group.
56
56. A 56 year old woman who has had chronic wrist pain since a fall several months
previously is referred for an MR arthrogram of her wrist with a suspected triangular
fibrocartilage complex (TFCC) tear. Which of the following would be the best
sequence for visualising a TFCC tear?
a. T1 axial
b. T2 coronal
c. Gradient echo sagittal
d. T2 sagittal
e. T1 sagittal
56. b. T2 coronal
The best sequence would be a T2 or T2* image for detecting a tear. This is also a useful
plane in which to assess for ulnar variance; positive ulnar variance has an association with
perforations. The central portion of the articular disc is not well vascularised and therefore
a tear in this portion will heal poorly. The peripheral portion, however, has been
vascularised.
57
57. A 64 year old woman undergoes MRI of her left knee for investigation of chronic knee
pain. Which of the following would be considered an abnormal finding on MR?
a. Bowing of the posterior collateral ligament on sagittal imaging
b. Low signal ACL on T1-weighted imaging
c. High signal around the MCL on T2* on coronal imaging
d. Low signal of the menisci on both T1- and T2-weighted imaging
e. Medial patellar plica
57. c. High signal around the MCL on T2* on coronal imaging
The only abnormal finding is the presence of high signal around the MCL on T2* imaging.
This would represent oedema or haemorrhage around the MCL and may be associated with
a tear. Bowing of the PCL occurs when the knee is extended. A medial patellar plica is a normal finding in approximately 50% of the population. This is an embryological
remnant from when the knee was divided into three compartments
58
58. A 53 year old woman attends A&E with a short history of dull right heel pain. She is
otherwise fit and well and there is no history of trauma. Plain radiographs of the right
foot and ankle reveal a 2 cm expansile non-aggressive lesion in the calcaneum. It has
a thin, well-defined sclerotic border. There is no periosteal reaction but there is a
small calcified central nidus. The most likely cause of the lesion is:
a. Aneurysmal bone cyst
b. Intra-osseous lipoma
c. Lipoblastoma
d. Fibrous dysplasia
e. Desmoplastic fibroma
58. b. Intra-osseous lipoma
The calcaneum is a common location for an intra-osseous lipoma. They do, however, also
occur in the extremities, skull and mandible. There is no periosteal reaction unless there is
an associated fracture. Imaging features would be similar to those of a unicameral bone cyst.
They are often asymptomatic but can present with localised bone pain
59
59. A three-year-old boy attends A&E with a history of a seizure. He has known congenital
cardiomyopathy. A chest radiograph shows sclerosis and expansion of several ribs.
Previous plain films have shown bone islands within the vertebrae and long bones and
bone cysts within the phalanges. Which of the following conditions would be likely to
underly these findings?
a. Down’s syndrome
b. Tuberous sclerosis
c. Sturge–Weber syndrome
d. Neurofibromatosis
e. Sarcoidosis
59. b. Tuberous sclerosis
This is a multi-system autosomal dominant disorder affecting the central nervous system,
kidneys, lung and heart. The classic triad of facial angiofibroma, epileptic seizures and
mental retardation is only seen in approximately 30% of patients. Skeletal abnormalities
include sclerotic calvarial patches or ‘bone islands’, thickening of diploe, expansion and
sclerosis of ribs and periosteal thickening of long bones. Gracile ribs are often seen in
association with Down’s syndrome
60
60. A 27 year old man falls onto his right hand during a game of rugby. He attends the
A&E department and a plain film of the right hand shows a comminuted fracture
through the base of the thumb metacarpal with an intra-articular component.
This is the description of which of the following fractures?
a. Rolando’s fracture
b. Bennett’s fracture
c. Gamekeeper’s thumb
d. Boxer’s fracture
e. Barton’s fracture
60. a. Rolando’s fracture
This is the classic description of a Rolando’s fracture. A Bennett’s fracture is also a fracture
of the base of the first metacarpal but with no comminution; this fracture is often less stable
than a Rolando’s fracture and more often requires surgical fixation. A ‘gamekeeper’s thumb’
often occurs as the result of forced abduction of the thumb and results in disruption of the
ulnar collateral ligament.