Musculoskeletal Flashcards
Progressive disease with genetic predisposition, loss of articular cartilage, & effects WB joints
Osteoarthritis
OA has cartilage degeneration with __________ inflammation
Minimal inflammation
A key characteristic of OA is ________ formation which may be seen on xray
Osteophyte formation
OA is associated with what conditions/RFs
Age, hormones, genetics, obesity, lack of physical activity, & metabolic abnormalities
What metabolic abnormalities is OA associated with
Acromegaly
Gout
Hyperthyroidism
OA has abnormal joint mechanisms. What are the 2 groups?
Congenital defects (SCFE & congenital hip dysplasia) Acquired defects (epiphysis dysplasia)
Condition where the protective cartilage on the ends of your bones wears down over time
OA
The primary symptom/complaint of OA is
Joint Pain
Describe the joint pain of OA
Localized
Asymmetrical
Increases with use
What are the features of OA
Herbeden's nodes at PIP Bouchard's leg deformities Fusiform swelling of joints Loss of ROM Brief morning stiffness Effusions/Crepitus Pain relieved with rest Genu Valgum
What is genu valgum
AKA knocked-knees
Severe lateral wear of the knee joint causing laxity of the medial ligament and knees jutting medially
What is the diagnostic of choice for OA
H&P is often sufficient
You believe you pt has OA and order some lab studies (fluid analysis) what might you find?
Synovial fluid debris
Absent of crystals
Absent of white cells/organisms
You believe you pt has OA and order some lab studies (serum analysis) what might you find?
Normal uric acid, CBC, & rheumatic panel
You believe you pt has OA and order some xrays what might you find?
Narrowing of joint space Osteophytes Chondral irregularly Boney cystic changes Articular surface sclerosis
What are osteophytes? What condition are they associated with
They are bony growths at the edge/surface of the bone/joint that show the bone is trying to repair itself; associated with OA
What is the proper medical management of OA
Pt education Exercise Bracing of joint PRN Cold therapy first followed by heat Activity modification (periods of activity followed by rest)
What is the primary treatment of OA
Acetaminophen recommended
What is the 2nd line treatment of OA
NSAIDs; specifically COX-2
- Celebrex
- Mobic
Why are NSAIDs 2nd line Tx for OA?
They are more effective but they have increased toxicity
What is the 3rd line Tx for OA
Cortisone injections
What is the 4th line Tx of OA
Hyaluronic acid injections (artificial synovial fluid to increase joint viscosity)
What is important to remember if you are considering giving a pt hyaluronic acid injections for OA
They can only be used for the knee joints
What is the ultimate Tx of OA? When is it indicated?
Arthroplasty
Indicated when conservative measures have failed