Musculoskeletal Flashcards

1
Q

ability of a muscle to shorten, accompanied by mechanical force generation: role in movement

A

contractility

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2
Q

capacity of muscle to respond to a stimulus

A

excitability

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3
Q

muscle can be stretched to its normal resting length and beyond to a limited degree

A

extensibility

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4
Q

ability of muscle to recoil to original resting length after being stretched

A

elasticity

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5
Q

What are a few properties of skeletal cells

A

-attached to bones
-nuclei are multiple per cell and peripherally located
-striated
-under voluntary and involuntary control

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6
Q

Fibrous connective tissues that connects muscle fibers to bones and serve as elastic anchors

A

Tendons

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7
Q

Muscle end attached to more stationary of two bones

A

origin or head

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8
Q

muscle end attached to bone with greatest movement

A

insertion

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9
Q

largest portion of the muscle between origin and insertion

A

belly

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10
Q

separate muscles that work together to cause a movement around a joint

A

synergists

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11
Q

muscle causing a particular action when it contracts

A

agonist

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12
Q

muscle working in opposition to agonist; typically relaxes during contraction of agonist

A

antagonist

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13
Q

What is parallel fiber arrangement?

A

parallel to the longitudinal axis of the muscle

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14
Q

What is pennate fiber arrangement?

A

fibers are at an angle to the longitudinal axis of the muscle
-typically generate a greater force per mass of tissue compared to parallel fiber arrangement, but have shorter range on motion

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15
Q

What surrounds muscle fibers?

A

connective tissue

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16
Q

What organizes muscle fibers into multiple bundles parallel to each other and provides a parallel component of elasticity?

A

connective tissue

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17
Q

plasma membrane of muscle fibers

A

sarcolemma

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18
Q

product of fusion of multiple cells sharing internuclear content

A

multinucleated syncytium

19
Q

the fundamental contractile structure (defined by z lines)

A

sarcomere

20
Q

bundles of myofilaments packed within the muscle fiber and constitute the contractile machinery

A

myofibrils

21
Q

prevents interaction between actin and myosin in absence of Ca2+

A

tropomyosin

22
Q

promotes a change in tropomyosin allowing binding of actin and myosin with binding of Ca2+

A

troponin

23
Q

at what point does ADP and Pi dissociate from the myosin head

A

power stroke

24
Q

what allows for the release of myosin from actin

A

ATP binding to myosin head

25
Q

rapid net redistribution of ions across the plasma membrane, driven by previously established concentration gradients (transmission of electrical signals)

A

action potential

26
Q

specialized ca2+ reservoir within cells

A

sarcoplasmic reticulum

27
Q

resides in the sarcolemma/t tubule, a voltage sensitive channel which opens in response to membrane depolarization, allows a slow influx of calcium

A

DHPR

28
Q

resides in SR membrane, opened directly by activated DHPR, allows release of Ca2+ stores in SR into the sarcoplasm

A

RyR

29
Q

ion pump protein principally responsible for moving Ca2+ from sarcoplasm into the SR and restoring the Ca2+ gradient to terminate contractile response

A

SERCA (SR Ca2+ ATPase)

30
Q

a motor neuron plus all the muscle fibers to which it connects

A

motor unit

31
Q

varying degrees of force produced by variations in number of motor units activated

A

graded contractions

32
Q

fibers per neuron can vary based on functional requirements of muscle in question

A

innervation ratios

33
Q

generates a contractile force of contraction that decays as fiber relaxes, stimulated by a single isolated electrical stimulus

A

twitch

34
Q

more frequent stimuli each production units of contractile force, next stimulus arrives before relaxation from previous stimulus is complete

A

summation of twitches

35
Q

frequency high enough to produce steady contraction (no relaxation) and maximal force development

A

tetanic contraction

36
Q

the effect of the series elastic component of the actively stretched muscle

A

elastic recoil

37
Q

in muscle stretched to an extreme via an autonomic nervous signal to contract and thus shorten, protecting the muscle

A

stretch relex

38
Q

high myosin ATPase activity, thus more rapid cross bridge cycling and high shortening velocity, fatigue rapidly

A

fast fibers

39
Q

low myosin ATPase activity and lower shortening velocity, fatigue more slowly

A

slow fibers

40
Q

numerous mitochondria, high capacity of oxidative phosphorylation, ATP production dependent on blood borne oxygen and fuel, contain myoglobin which increase rate of oxygen capture in fiber

A

oxidative fibers

41
Q

high concentration my glycolytic enzymes and glycogen, larger and have more thick and thin filaments and can develop more tension, fatigue rapidly

A

glycolytic fibers

42
Q

low intensity exercise effects

A

oxidative fibers

43
Q

high intensity exercise effects

A

glycolytic fibers

44
Q

ability to adapt in size and composition to needs and activity

A

plasticity