Muscular System (Review & Comprehension) Flashcards
What are the functions of the Muscular System?
- Movement of the body
- Maintainance of posture
- Respiration
- Production of body heat
- Constriction of organs and vessels
- Communication
- Constraction of the heart
Define the Contractility, Excitability, Extensibility, and Elasticity.
Contractility - ability to shorten with force
Excitability - Capacity to respond to a stimulus
Extensibility - ability to be stretched to their normal resting length
Elasticity - ability to recoil to their original form
List the connective tissue layers associated with muscles
- The endomysium
- The perimysium
- The epimysium
What are muscle fasciculi?
numerous visible bundles that make up the muscle
what is muscle fiber?
several muscle cells that compose a fasciculus
Explain the irrelevance of the structural relationship among sarcomeres, T tubules, and the sarcoplasmic reticulum.
The sarcomere is going to form myofibrils through end-to-end connections. During muscle contraction, the T tubules are stimulated by the action potential to further deliver this stimulus to the sarcoplasmic reticulum to release “divalent calcium” ions.
What is sarcomere?
highly ordered, repeating units of actin + myosin myofilaments; joined end to end to form myofibril
Explain the resting membrane potential and how it is produced.
What generates the resting membrane potential is the K+ that leaks from the inside of the cell to the outside via leak K+ channels and generates a negative charge in the inside of the membrane vs the outside. At rest, the membrane is impermeable to Na+, as all of the Na+ channels are closed.
Describe the composition of a myofibril.
Describe the structure of actin and myosin myofilaments.
The myofibrils are made up of thick and thin myofilaments, which help give the muscle its striped appearance.
The thick filaments are composed of myosin, and the thin filaments are predominantly actin, along with two other muscle proteins, tropomyosin, and troponin.
Describe the production of an action potential.
A skeletal muscle action potential is generated when the motor endplate potential is sufficient to raise the surrounding sarcolemmal potential above the threshold for activation of the voltage-gated Na+ channels that are abundant throughout the sarcolemma.
What is the neuromuscular junction and what happens there?
A neuromuscular junction (or myoneural junction) is a chemical synapse between a motor neuron and a muscle fiber. It allows the motor neuron to transmit a signal to the muscle fiber, causing muscle contraction. Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy.
Describe the sliding filament model of muscle contraction
The sliding filament model describes the process used by muscles to contract. It is a cycle of repetitive events that causes actin and myosin myofilaments to slide over each other, contracting the sarcomere and generating tension in the muscle.
Explain how an action potential results in muscle contraction.
A Muscle Contraction Is Triggered When an Action Potential Travels Along the Nerves to the Muscles. The chemical message, a neurotransmitter called acetylcholine, binds to receptors on the outside of the muscle fiber. That starts a chemical reaction within the muscle.
Define muscle twitch, tetanus, and recruitment.
A muscle twitch is an involuntary contraction of the fibers that make up a muscle. There are 3 phases; Lag/Latent, Contraction and Relaxation Phase
Tetanic contraction (tetanus) occurs when stimulation frequency is so rapid that there’s no relaxation.
Recruitment - the no. of muscle fibers contraction is increased by the increasing no. of motor units stimulated + muscle contracts with more force.
Describe two ways energy is produced in skeletal muscle.
Aerobic respiration - which produces ATP and breaks down glucose; requires oxygen
Anaerobic respiration - no oxygen; breaks down glucose to yield ATP and lactic acid
Explain fatigue
Fatigue is often thought of as the state of feeling very tired, weary, or sleepy resulting from various sources such as insufficient sleep, prolonged mental or physical work, or extended periods of stress or anxiety.