Muscles Flashcards
Cardiac Muscle Tissue
Forms most of the heart wall
Is striated
Is involuntary
Can regenerate under certain conditions
Skeletal muscle tissues
Is attached to bones and moves part of the skeleton
Is striated (alternating light and dark bands)
Is voluntary (conscious control)
Has limited capacity for regeneration
Smooth muscle tissue
Located in the walls of hollow internal structures like blood vessels, airways and the stomach
Not striated
Is voluntary
Compared to other muscles it has a considerable capacity to regenerate
Functions of the muscle tissue
Producing body movements like running or walking
Stabilizing body positions like sitting or standing
Regulating organ volume by using ring muscles called sphincters to close off outlets from the stomach and bladder
Moving substances within the body like blood, food, sperm, eggs
Producing heat from the contraction of muscles
Skeletal muscle is composed of
Cells called muscle fibers
Epimyseum
CT that wraps the muscle fibers
Perimyseum
CT that surrounds a fascicles which is a bundle of 10-100 muscle fibers
Endomyseum
CT that wraps each individual muscle fiber
Tendon
A cord formed from the extension epimyseum, perimyseum, and endomyseum. It attaches the muscle to a bone.
What are skeletal muscles supplied with?
Nerves and blood vessels which provide nutrients and oxygen for the production of ATP
Sarcolemma
The name for the plasma membrane
T-tubules (transverse tubules)
Tunnel like inward extensions of the sarcolemma
Nuclei
Each muscle fiber contains multiple nuclei
Sarcoplasm
The name for the muscle fibers cytoplasm
Mitochondria
Makes large amounts of ATP for muscle contraction
Sarcoplasmic Reticulum (SR)
Similar to the endoplasmic reticulum; it stores calcium ions needed for muscle contraction
Myoglobin
Reddish pigment that stores oxygen until it is needed by the mitochondria to produce ATP
Myofibrils
Cylindrical structures within and extending the length of the muscle fiber
They contain thin and thick filaments (do not run the entire length of the muscle fiber)
Thick filaments
Made up of protein called myosin
Thin filaments
Contains the protein actin
Sarcomere
Compartment within the myofibril formed from the filaments of the thick and thin filaments
Basic functional unit of the muscle fiber
Z-discs
Zig zag zones that separate one sarcomere from the next
Sliding filament mechanism
During muscle contraction myosin heads of the thick filaments pull and slide on the thin filaments causing the thin filaments to pull toward the center of the sarcomere
When the filaments slide past each other it causes the sarcomere to get shorter causing the shortening of the entire muscle fiber
Ca+ must be high enough and there must be enough ATP available
Neuromuscular Junction
Nueromuscular junction is the synapse (connection) between a motor neuron and muscle fiber
Motor Neuron
A nerve cell that delivers an electrical signal called a muscle action potential (nerve impulse)
The message is what tells the muscle it’s time to contract
Motor unit- a single motor neuron plus all of the muscle fibers it stimulates. Stimulation of one motor unit causes all the fibers in the motor unit to contract at the same time
Axon terminal- the end of the axon (long process) of a motor unit that approaches but does not touch the sarcolemma of a muscle fiber. The ends of the axon terminal enlarge into synaptic end bulbs. The synaptic end bulbs contains sacs called synaptic vesicles which are filled with a chemical called acetylcholine (ACh) a neurotransmitter
Synaptic cleft
The space between the axon terminal and the sarcolemma of a muscle fiber
Motor end plate
The region of the sarcolemma near the axon teriminal; it contains millions of ACh receptors
When nerve impulses arrive at the synaptic end bulbs:
ACh is released from the synaptic vesicles. It diffuses across the synaptic cleft.
ACh binds to the receptors in the motor end plate. This opens ion channels in the sarcolemma that allow sodium ions to flow across the membrane and enter the muscle fiber
As a result the sodium ions rushing in, actin potential is generated which flows along the sarcolemma and through the t-tubules
Acetylholinesterase (AChE) breaks down ACh
Two things are needed for muscle contraction
Ca+
Energy
When a muscle fiber is relaxed:
Ca+ is found in the sarcoplasmic reticulum. When muscle action potential travels into the SR Ca12 is released into the sarcoplasm where it uncovers myosin biding site of the thin filaments
Contraction occurs:
As ATP is split into ADP and P and energy is transferred into myosin
The power stroke occurs
Myosin, the thick filaments slide the thin filaments, actin toward the center of the sarcomere
Energized myosin heads
Form cross bridges that attach to actin
Relaxation
ACh is broke down by AChE
Ca+2 are pumped back into the sarcoplasmic reticulum
Rigor mortis
After a person dies Ca+2 leaks out of the sarcoplasmic reticulum causing the thin filaments to slide and the muscles to stiffen
Lasts about 24 hours
Muscle tone
There is a continual involuntary activation of a small number of motor units even when the whole muscle is not contracting
Needed to maintain posture
Flaccid
Very limp