Muscleoskeletal

Question 0

Salicylate’s/ASA. Side effects

Answer 0

(First line) (give with food)

• side effect: GI bleeds, tinnitus, bruising, hypersensitivity, GI ulcers
• monitor allergic reaction, edema, weight gain, constipation

Question 1

Meds for rheumatoid arthritis

Answer 1

ASA, NSAID, COX2 inhibitor, corticosteroids and analgesics

Question 2

ASA can’t be replaced by

Answer 2

Acetaminophen for anti inflammatory

Question 3

ASA can decompose by

Answer 3

Humidity (vinegar smell)

Question 4

Ecotrin

Answer 4

Enteric coated ASA

Question 5

Bufferin

Answer 5

Buffered ASA (prevent GI upset)

Question 6

Tylenol

Answer 6

Can be use for ASA

Question 7

COX 2 inhibitor. Side effects

Answer 7

Celebrex (celecoxid)

• GI upset (admin with food)
• check allergies to ASA

Question 8

Corticosteroids given

Answer 8

PO, IM, intra articular (teach pt not to over stress joint)

Question 9

Long term side effects with corticosteroids

Answer 9

High sodium, low potassium, leak of calcium in bones, high hydrochloric acid, low mucus production and adrenal crisis

Question 10

Systemic metabolic side effects with corticosteroids

Answer 10

Interference of protein/fats/carbs absorption, hyperglycemia, suppress inflammatory process and comprised immune system

Question 11

Corticosteroids side effects

Answer 11

Low fluid, electrolyte imbalance and fat deposit (moon face, buffalo hump)

Question 12

Adrenal crisis

Answer 12

Life threatening if steroids are stopped suddenly

-cause hypotension, muscle weakness, headache, N/V/D

Question 13

Osteoarthritis drugs

Answer 13

Naprosyn, Feldene, Flexeril, analgesic

Question 14

Osteoarthritis

Answer 14

Steroids usually injected intra articular due to it being a local disease

Question 15

Analgesics used for pain relief for

Answer 15

Fractures, back injuries and hip/knee surgery

Question 16

Anti inflammatory drugs work by

Answer 16

Blocking postiglandulins

-steroids/NSAID decrease production of postiglandulins

Question 17

To decrease suppression of adrenal activity

Answer 17

Give steroids every other day than everyday

Question 18

Elderly post op

Answer 18

Start with lower dosage first than higher

Question 19

Demerol (meperidine)

Answer 19

CNS depressant

• avoid giving with another CNS depressant and alcohol
• Narcotic analgesic
• monitor resp

Question 20

Opioids

Answer 20

Depress resp, CNS and addictive

Question 21

Gout drugs

Answer 21

Colchicine (treat), allopurinol/zyloprim, probenicid/benemid, anturane/sulfinpyrazone, butazolidin and indocin (reduce Uric acid and increase kidney production)
- increase fluid 3000mls daily

Question 22

Drug interaction

Answer 22

Effects of a drug are diminished by another drug

Question 23

Drug tolerance

Answer 23

Body requires increased amount to obtain relief

Question 24

Minimum effective concentration

Answer 24

Minimal amount of drug needed for response

Question 25

Polypharmacy

Answer 25

Multiply drugs being used

Question 26

Drug interaction

Answer 26

Effects of a drug are diminished by another drug

Question 27

COX2

Answer 27

Prostaglandins are produced which stimulate inflammation

Question 28

COX1

Answer 28

Considered protective in blood vessels, stomach and kidneys. (Causes constriction and dilation)

Question 29

NSAID

Answer 29

Admin with food,milk and antacid to decrease GI upset | -check history if allergic reactions

Question 30

DMARDS

Answer 30

Disease modifying anti rheumatic drug | - doesn't treat pain or inflammation, it slows/arrest the degenerative nature of arthritis

Question 31

Gold compound

Answer 31

Reduces progression of RA, most useful before extensive degeneration of joints

Question 32

If patients allergic to ASA don't give

Answer 32

Ibuprofen, fenoprofen, calcium and naproxen

Question 33

ASA is commonly given for

Answer 33

Is analgesic., antipyretic and anti inflammatory agents

Question 34

ASA inhibits

Answer 34

Prostaglandins which lead to elimination of sodium (sodium May be restricted)

Question 35

Patient teaching with corticosteroids

Answer 35

Decrease sodium, increase calcium, potassium supplements, carry ID bracelet and take in morning to prevent insomnia