Muscle tissue Flashcards

1
Q

Overview of muscle form & function

A
  • Muscle tissue responsible for body movement
  • Produce heat (as much as 70% of body heat)
  • Maintenance of posture
  • Muscle cells consist of filaments containing proteins
  • actin and myosin
  • together enable muscle contraction
  • Three types of muscle tissue in the vertebrate body
  • skeletal muscle
  • smooth muscle
  • cardiac muscle
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2
Q

Skeletal muscle tissue

A
  • Consists of bundles of long cells that are called muscle fibers
  • Form by the fusion of many cells-resulting in multiple nuclei in each muscle fiber
  • Arrangement of contractile units (sarcomeres) along thefibers give the cells a striped (striated) appearance
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3
Q

Skeletal muscle tissue function

A
  • Attached to bones by tendons
  • Skeletal muscle, or striated muscle, is responsible for voluntary movements
  • Produce ~70% of body heat, through involuntary movement, i.e. shivering
  • Maintenance of posture
  • In adult mammals, building muscle increases the size but not the number of muscle fibers
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4
Q

Smooth muscle tissue

A
  • Lacks striations
  • Found in the walls of the digestive tract, urinary bladder, arteries, and other internal organs
  • Spindle shaped
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5
Q

Smooth muscle tissue function

A

•Forms the supporting tissue of blood vessels, hollow internal organs, such as the stomach, intestine, and bladder
•Responsible for involuntary body activities
e.g.
•churning of the stomach
•constriction of arteries

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6
Q

Cardiac muscle tissue

A
  • Striated like skeletal

* Branched fibers that interconnect via intercalated disks

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7
Q

Cardiac muscle tissue function

A
  • Cardiac muscle forms the contractile wall of the heart
  • Has similar contractile properties as skeletal muscle
  • Branched fibers relay signals from cell to cell and help synchronize heart contraction
  • Involuntarycontrol
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8
Q

The Role of Calcium and Regulatory Proteins

A
  • The regulatory protein tropomyosin and the troponin complex, a set of additional proteins, bind to actin strands on thin filaments when a muscle fiber is at rest
  • This prevents actin and myosin from interacting
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9
Q

what is required for a muscle fiber to contract?

A
  • For a muscle fiber to contract, myosin-binding sites must be uncovered
  • This occurs when calcium ions (Ca2+) bind to the troponin complex and expose the myosin-binding sites
  • Contraction occurs when the concentration of Ca2+is high; muscle fiber contraction stops when the concentration of Ca2+is low
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10
Q

what is thee stimulus leading to the contraction of a muscle fiber?

A
  • The stimulus leading to contraction of a muscle fiber is an action potential in a motor neuron that makes a synapse with the muscle fiber
  • The synaptic terminal of the motor neuron releases the neurotransmitter acetylcholine
  • Acetylcholine depolarizes the muscle, causing it to produce an action potential
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11
Q

what happens after acetylcholine depolarises the muscle, causing it to produce an action potential?

A

•Action potentials travel to the interior of the muscle fiber along transverse (T) tubules•The action potential along T tubules causes the sarcoplasmic reticulum (SR)to release Ca2+•The Ca2+binds to the troponin complex on the thin filaments•This binding exposes myosin-binding sites and allows the cross-bridge cycle to proceed

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