Muscle Relaxants

Question 1

Succinylcholine (anectine, quelicin)

class

Answer 1

muscle relexant
depolarizing
**first choice

Question 2

Succinylcholine (anectine, quelicin)

dose

Answer 2

IV 0.5- 1.0 mg/kg

IM 2-4 mg/kg

Question 3

Succinylcholine (anectine, quelicin)

onset/peak/duration

Answer 3

onset: 30-60 sec
peak:
duration: 3-5 min

Question 4

Succinylcholine (anectine, quelicin)

MOA

Answer 4

• “basically 2 acetylcholine molecules bound together”
  1. ) attaches to 1 or both alpha subunits of nicotinin acetylcholine receptors & mimics action of acetylcholine

2. ) depolarizing post junctional membran
3. ) result: neuromuscular blockade d/t prolonged depolarized post junctional membrane cannot respond to Ach

Question 5

Succinylcholine (anectine, quelicin)

Phase 1 blockade

Answer 5

enhanced by actylcholinesterase drugs

Question 6

Succinylcholine (anectine, quelicin)

Phase 2 blockade

Answer 6

unknown- fill out

Question 7

Succinylcholine (anectine, quelicin)

effects

Answer 7

dysrhythmias
decreased HR (esp in peds)

Question 8

Succinylcholine (anectine, quelicin)

caution & extra

Answer 8

-MH trigger
-atropine will prevent bradycardia at first, but not with
second dose
-serum K will be increased, caution in burns and
demyelinating disorders