Muscle Physiology Flashcards
What is the area where the neuron connects with the muscle?
Muscular Junction
What channels are found on the sarcolemma by the synaptic cleft?
Chemically gated Na+ channels
What neurotransmitter is used when activating a muscle?
Acetylcholine
What happens when the Na+ channels are open on the sarcolemma?
The positive charge will spread along the membrane of the muscle through the T-tubules and activate voltage gated Ca+ channels
Whats the name of the cell membrane of muscle fibers?
Sarcolemma
What are the three parts of thin filaments?
- Troponin- Tropomyosin- Actin
What are extensions of the sarcolemma that transmit the impulse to penetrate the muscle fiber?
T-tubule
What are the structures on a muscle fiber that are used to store Ca+?
Sarcoplasmic Reticulum
When the electrical energy is traveling through the T-tubule it stimulates the release of what?
Ca+ through voltage gated Ca+ channels on the sarcoplasmic reticulum
What protein does Ca+ bind to on the thin filament?
Troponin
What happens when Ca+ is bound to troponin?
Troponin reorients itself while moving tropomyosin with it, thus exposing the active sites of actin
What is troponin attached with?
Tropomyosin
What does tropomyosin cover during rest?
Active site on actin
What protein is the thick filament made of?
Myosin
What are the golf club shaped heads called on thick filament?
Myosin Head
What is needed in order for myosin to attach to actin active sites?
ATP
What two things is ATP used for during muscle contraction?
- Move myosin head- Detach myosin head from actin active sites
How does a muscle fiber contract? Part or all of the fiber?
Maximally (the entire fiber must contract)
What is a the basic unit of striated muscle tissue?
Sarcomere
In what order is muscle organized?
- Epimysium (Muscle)- Perimysium (Fascicle)- Endomysium (Muscle Fiber)
Where are the think filaments and thin filaments attached at?
Z-lines
How is muscle attached to bone?
Tendons (CT structures)
What is another term for a muscle cell?
Muscle Fiber
What does a muscle fiber consist of?
Several myofibrils