muscle excitation Flashcards
skeletal muscle
-long cylindrical cells
- many nuclei per cell
- striated: has tiny bands that run across the muscle cell
- voluntary
-rapid contractions
cardiac muscle
-branching cells
- one or two nuclei per cell
- striated
- involuntary
-medium speed contractions
smooth muscle
- fusiform cells
-one nucleus per cell
-nonstriated
-involuntary
-slow, wave-like contractions - found in hollow organs
electrical disequilibrium
- the body is in a state of electrical disequilibrium because active transport of oils across the cell membrane creates an electrical gradient
- although the body is electrically neutral, cells have excess negative ions on the inside and their matching positive ions are found on the outside.
electrochemical gradient
- the inout of energy to transport ions across a membrane has created an electrical gradient
- the active transport of positive ions out of the cell has created a chemical gradient. The combination of an electrical gradient is called an electrochemical gradient
- the cell remains in osmotic equilibrium, physiological measurements are carried out on a relative scale
cell membrane
- the -ve ions will try and move down the electrical gradient and follow the +ve ion out of the cell, but the membrane inhibits its flow as its a good insulator
- prevents the movements of separate charges
resting membrane potential
- electrical gradient across the cell membrane
- resting: membrane potential has reached a steady state and is not changing
- potential: electrical gradient created by active transport of ions is a source of stored or potential trial energy
potassium ions and resting membrane potential
- potassium ion leak out of cell down its concentration gradient.
- excess -ve charge build up in side the cell as Pr negative cannot cross the membrane. An electrical gradient is formed
- -ve charges attract K+ ions back into the cell down the electrical gradient.
- net movement of k+ stops. the membrane potential at which the electrical gradient opposes the chemical gradient is known as the equilibrium potential
neuromuscular junctions
The nerve impulse reaches the neuromuscular junction (myoneural junction).
- acetylcholine is released from the motor neuron
- acetylcholine binds with receptors in the muscles membrane to allow sodium ions to enter the muscle.
excitation of muscles steps
- nerve impulse reaches neuromuscular junction
- acetylcholine is reached from motor neuron
- acetylcholine binds with receptors in the muscles membrane to allow sodium to enter
- sodium influx will generate an action potential in the sarcolemma
- action potential down T tubule
- sarcoplasmic reticulum releases calcium
- calcium binds with troponin to move the troponin, tropomyosin complex
- binding sites in the actin filament are exposed
motor unit
A motor unit is all the muscle cells controlled by one nerve cell.
muscle tonus and tetany
muscle tonus
- tightness of a muscle, some fibres always contracted
tetany
- sustained contraction of a muscle, result of a rapid succession of nerve impulses
refractory period
- brief period of time in which muscle cells will not respond to a stimulus