Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

2MB Musculoskeletal (My version) > Muscle Disease > Flashcards

Muscle Disease Flashcards

1
Q

What is the difference between polymyositis and dermatomyositis?

A

Dermatomyositis = polymyositis + skin changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The risk of malignancy increases with polymyositis and dermatomyositis. True/False?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

List the classic presenting MSK features of poly/dermato -myositis

A

Muscle weakness that worsens over months
Symmetrically affected
Myalgia
Difficulty with daily tasks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

List investigations for poly/dermato -myositis

A 
Inflammatory markers
Muscle enzyme (CK)
Autoantibodies
Electrolytes
Electromyography
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which antibodies are associated with poly/dermato -myositis?

A

ANA

Anti-Jo-1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the definitive test for poly/dermato -myositis?

A

Muscle biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

List the main treatment for poly/dermato -myositis

A

Steroids
Immunosuppression (methotrexate, azathioprine)
Ciclosporin
Rituximab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the steroid usually used for poly/dermato -myositis?

A

Prednisolone 40mg daily

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Inclusion body myositis is more common in males. True/False?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Is muscle weakness in inclusion body myositis usually symmetrical or asymmetrical?

A

Asymmetrical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

CK levels in inclusion body myositis are increased to a lesser fold compared to poly/dermato -myositis. True/False?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Inclusion body myositis is associated with anti-Jo-1 antibody. True/False?

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Polymyalgia rheumatica is associated with which arteritic disease?

A

Giant cell arteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Muscle weakness if a feature of polymyalgia rheumatica. True/False?

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

List the common features of polymyalgia rheumatica

A

Morning stiffness - can’t get out of bed
Fatigue
Anorexia
Reduced movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the mainstay of treatment for polymyalgia rheumatica?

A

Low dose steroid - usually rapid/dramatic response

17
Q

What is the commonest cause of chronic MSK pain?

A

Fibromyalgia

18
Q

Is fibromyalgia inflammatory?

A

No

19
Q

Fibromyalgia is commoner in which sex?

A

Women

20
Q

List some clinical features of fibromyalgia

A 
Broken sleep
Pain all over body
Pins and needles
Headaches
Depression
Tenderness on soft tissues

2MB Musculoskeletal (My version) (19 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions