muscarinic agonist/ACh mimetics Flashcards
what are the ACh mimetic drugs?
methacholine chloride
carbachol chloride
bethanechol chloride
pilocarpine
cevimeline
which are the non-traditional SAR ACh mimetic drugs?
pilocarpine
cevimeline
what are the reversible AChE inhibitor drugs?
physotigmine
neostigmine
pyridostigmine
carbaryl
edrophonium chloride
which ones of the AChE inhibitor drug has NO CNS effect?
neostigmine
pyridostigmine
what are the irreversible AChE inhibitor drugs?
sarin
echothiophate
malathion
what are the muscarinic antagonists?
atropine
scopolamine
ACh is synthesized from what amino acid?
serine
what kind of agonist is Chantix?
partial agonist at alpha-4 and beta-2
what are the selective alpha-1 agonist: phenylethanolamine drugs?
metaraminol
methoxamine
phenylephrine
what are the selective alpha-1 agonist: 2-arylimidazoline drugs?
xylometaZOLINE
oxymetaZOLINE
tetrahydroZOLINE
naphaZOLINE
what are the selective alpha-2 agonist drugs?
cloniDINE*- 1st in class prototype
tizaniDINE
apracloniDINE
brimoniDINE
what are the common functional groups in selective alpha-agonists?
halogen
guanidium group
what are the selective alpha-2 agonist drugs that have the opened ring system, analog of Clonidine?
guanabenz
guanfacine
which alpha agonist that is general for alpha receptors but can be regards as selective alpha-2 agonist?
methyldopa
what are the selective beta-1 agonist drugs?
dopamine
dobutamine
what are the indications for beta-1 agonists?
cardiac stimulant after surgery
CHF
what are the selective beta-2 agonists (short-acting)?
albuterol
pirbuterol
terbutaline
what are the selective beta-2 agonists (long-acting)?
salmeterol
formoterol
indacaterol
what are the nonselective alpha antagonists?
phenoxybenzamine
TOLAZOLINE
phentolamine
what are the selective alpha-1 antagonists?
praZOSIN
doxaZOSIN
teraZOSIN
which is the most common selective alpha-1A antagonist?
tamsuloSIN
what are the nonselective beta antagonists?
propranolol
dichloroisoproterenol
pronethalol
what’s an exam of a selective beta-1 antagonist (short-acting)?
esmolol
what are the serotonin receptor agonists?
the triptan anti-migraine meds
what are the beta antagonists used for migraine prevention?
metoprolol
propranolol
timolol
ALL CONTRAINDICATED IN ASTHMA PATIETNS
what AEDs can be used for migraine prevention?
valproate: depakote or depakote er
topamax
what antidepressant can be used for migraine prevention?
TCA: amitriptyline
SNRI: venlafaxine
what class of drug is for nausea/vomiting?
5-HT3 receptor antagonist
what is a common anti nausea/vomit drug in 5-HT3R antagonist?
zofran
