Murtagh's triads Flashcards

1
Q

dry eyes + dry mouth + arthritis =

A

Sjogren syndrome

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2
Q

Arthralgia + weight loss + fever (+/- skin lesions) =

A

polyarteritis nodosa

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3
Q

malaise + painful shoulder girdle + morning stiffness (>50 years) =

A

polymyalgia rheumatica

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4
Q

fatigue + headache + jaw claudication =

A

temporal arteritis

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5
Q

Malaise + URIs (e.g. rhinitis, sinusitis) + LRTs (e.g. wheeze, cough) =

A

Wegener granulomatosis

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6
Q

Asthma + rhinitis + vasculitis + hypereosinophilia =

A

Churg-Strauss vasculitis

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7
Q

Fatigue + psychiatric symptoms + myoclonus

A

CJD

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8
Q

Tiredness + husky voice + cold intolerance

A

Hypothyroidism (myxoedema)

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9
Q

Anxiety + weight loss + weakness

A

Thyrotoxicosis

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10
Q

Nasal problems + fitting problems (eg rings, shoes) + sweating

A

Acromegaly

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11
Q

Weakness + polyuria + polydipsia

A

Diabetes insipidus

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12
Q

Female: amenorrhoea + loss of axillary and pubic hair + breast atrophy
Male: reduced libido + impotence + loss of body hair

A

Hypopituitarism

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13
Q

Fatigue + anorexia, nausea, vomiting + abdominal pain (+/- skin discolouration)

A

Addison disease

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14
Q

Plethoric moon face + thin extremities + muscle weakness

A

Cushing syndrome

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15
Q

Weakness + constipation + polyuria

A

Hypercalcaemia

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16
Q

Cramps + confusion + tetany

A

Hypocalcaemia

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17
Q

Discoloured urine + peri-orbital oedema + oliguria

A

post-streptococcal glomerulonephritis

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18
Q

Proteinuria + generalised oedema + waxy pallor

A

Nephrotic syndrome

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19
Q

Dysuria + fever + perineal pain

A

Acute prostatitis

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20
Q

Poor urine flow + straining to void + frequency

A

Bladder outlet obstruction

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21
Q

Unilateral sensorineural deafness + tinnitus + unsteady gait (+/- facial palsy)

A

Acoustic neuroma

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22
Q

Acute vertigo + nausea + vomiting

A

Vestibular neuronitis

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23
Q

Acute vertigo + nausea + vomiting + hearing loss +/- tinnitus

A

acute labyrinthitis

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24
Q

Vertigo + vomiting + tinnitus + sensorineural deafness

A

Meniere syndrome

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25
Q

Malaise + cough + weight loss

A

lung cancer

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26
Q

Haematuria + loin pain + palpable kidney mass

A

kidney cell cancer

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27
Q

haematuria + abdominal mass + malaise

A

Wilms tumour

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28
Q

Abdominal discomfort + anorexia + abdominal bloating/distension

A

ovarian cancer

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29
Q

Blood in stools + abdominal discomfort + change in bowel habit

A

Colon cancer

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30
Q

Jaundice + anorexia + abdominal discomfort/pain

A

pancreatic cancer

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31
Q

Malaise + pallor + bone pain

A

ALL

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32
Q

Malaise + pallor + oral problems

A

AML

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33
Q

Fatigue + fever/night sweats + abdominal fullness (splenomegaly)

A

CML

34
Q

Fatigue + weight loss + fever/night sweats + lymphadenopathy

A

CLL

35
Q

Malaise + fever/night sweats + pruritis

A

Hodgkin lymphoma

36
Q

Malaise + fever/night sweats + lymphadenopathy

A

non-Hodgkin lymphoma

37
Q

Weakness + unexplained back pain + susceptibility to infection

A

Multiple myeloma

38
Q

Severe abdominal pain + abnormal illness behaviour + “red” urine

A

Acute intermittent porphyria

39
Q

Child:

Arthralgia (lower limbs) + rash (buttocks, legs) +/- abdominal pain

A

Henoch-Schonlein purpura

40
Q

Child:

Respiratory symptoms + vomiting + mental changes +/- seizure/coma

A

Reye syndrome

41
Q

Child

Pallor + drowsiness + fever

A

Meningitis

42
Q

Child

Pallor + abdominal pain (severe, intermittent) + inactivity

A

intussusception

43
Q

Child

Malaise + fever + polyarthritis (flitting) +/- rash +/- chorea

A

Acute rheumatic fever

44
Q

Child <12 months

drowsiness + cough + wheeze

A

bronchiolitis

45
Q

Baby <3 months

Weakness + weight loss + vomiting (projectile)

A

pyloric stenosis

46
Q
Neonate
Vomiting (after first feeds) + drooling + abdominal distension
A

oesophageal or duodenal atresia

47
Q

Child

Malaise + pallor + bone pain

A

Acute lymphoblastic leukaemia

48
Q

Child

Malaise + pallor + oral problems(gingival hypertrophy, bleeding, ulceration)

A

Acute myeloid leukaemia

49
Q

Child

Abdominal pain + pallor + anorexia/nausea/vomiting

A

acute appendicitis

50
Q

Child

Abdominal pain + malar flush + fever +/- URTI

A

mesenteric adenitits

51
Q

Child (during gastro epidemic)

Malaise (extreme) + diarrhoea + severe abdominal pain

A

Haemolytic uraemic syndrome

52
Q

Child

Drowsiness + tachypnoea + chest wall recession

A

pneumonia

53
Q

Child

Drowsiness + fever + purpuric rash

A

meningococcal infection

54
Q
Child
Lethargy (extreme) + drooling saliva + stridor
A

Acute epiglottitis

55
Q

Child

URTI + barking cough + stridor

A

croup

56
Q

Child

Cough + wheeze + chest wall recession

A

asthma or inhaled FB

57
Q

Child
Fever + conjunctivitis + skin changes (cracked red lips, maculopapular rash, erythema of palms/soles, desquamation fingertips)

A

Kawasaki disease

58
Q

Child

Large ears + long narrow face + large genitals

A

Fragile X

59
Q
Child
Small extremities (hands, feet, genitals) + narrow forehead + eating disorder
A

Prader-Willi syndrome

60
Q

Child

“Elfin” face + low set ears + cardiac murmur

A

Williams syndrome

61
Q

Female

Short + webbed neck + pigmented naevi +/- cardiac disorder

A

Turner syndrome

62
Q

Child

Short + webbed neck + facial disproportion (broad forehead, ptosis, low-set ears) +/- cardiac disorder

A

Noonan syndrome

63
Q

Child

Malaise + abdominal pain (vague) + abnormal behaviour

A

lead poisoning

64
Q

<2 years

Lethargy + irritability + pallor

A

iron deficiency anaemia or thalassaemia major

65
Q

Child

Fever + malaise (extreme) + a/n/v +/- anaemia

A

neuroblastoma

66
Q

child

headache + a/n/v + ataxia

A

medulloblastoma

67
Q

Older children: male

snorting, blinking etc. + oral noises (grunts, hisses) +/- loud expletives

A

Tourette syndrome

68
Q

Older children

Irritability + disorders of appetite + abdominal pain (vague)

A

Substance abuse

69
Q

Older children

Mid to low back pain/discomfort + inability to touch toes + kyphosis

A

Scheuermann disorder

70
Q
Older children
Knee pain (after activity) + tender knee 'lump' + pain on kneeling
A

Osgood-Schlatter disorder

71
Q

Adolescent

Limp + knee pain + hip pain

A

Slipped capital femoral epiphysis

72
Q

Patch of complete hair loss + clean scalp + exclamation mark hairs

A

alopecia areata

73
Q

Stressful event + 2-3 months gap to diffuse hair loss + ‘white bulbs’

A

teflogen effluvium (increased shedding of hairs in the telogen phase)

74
Q

Fair females <5 + thin wispy hair + easy loss with pulling

A

loose anagen syndrome (improves with age)

75
Q

Angina + dyspnoea + blackout or lightheadedness

A

aortic stenosis

76
Q

Severe seizures (peak age 3-5) + mental retardation + characteristic EEG

A

Lennox-Gastaut syndrome (myoclonic epilepsy of infancy)

77
Q

Retro-orbital headache + rhinorrhoea + lacrimation

A

cluster headache

78
Q

Drowsiness + vomiting + seizure

A

raised intracranial pressure

79
Q

Occipital headache + vomiting + neck stiffness

A

SAH

80
Q

Headache + visual disturbance + nausea (obese female)

A

idipathic intracranial hypertension

81
Q

Fever (+/- rigors) + upper abdominal pain + jaundice

A

acute cholangitis (Charcot triad)

82
Q

Jaundice + constitutional symptoms (malaise, anorexia, weight loss) + epigastric pain (radiating to back)

A

pancreatic cancer