Multiple sclerosis (MS) [Rare Qs] Flashcards
All u need to know
Chronic immune mediated inflammatory conditions of CNS
- Affects brain, optic nerves, spinal cord
- Leads to severe disability
- No cure
- Treatments used to reduce freq & duration of relapses and to slow/prevent disability.
Drugs
Interferon beta
Glatiramer acetate
Fingolimod (Oral for high active disease)
Natalizumab (only for rapidly evolving disease state)
- Regular vit D - helps prevent relapse
During relapse - corticosteroid recommended
- Oral methylprednisolone - 1st line
ALT IV form if above fail/unsuitable
Fatigue/Impaired mobility
Amantadine, SSRi, modafinil.
- Vit b12 injection not recommended
- Fampridine for walking Pts
Spasticity
(Stiff/Rigid muscles)
1st line - Baclofen
ALT Gabapentin
Adjunct 4 week trial cannabis.
Oscillopsia
Visual issues everything is moving but nothing is
- Gabapentin 1st line
Emotional issues
Amitriptyline
ALT Memantine
