Multiple Sclerosis Flashcards
Definition of Multiple Sclerosis
Inflammatory disorder of an unknown cause affecting CNS characterised by demyelination and scarring
Incriminating factors of Multiple Sclerosis
Infection (viral)
Autoimmune
Genetic susceptibility
Precipitating factors of Multiple Sclerosis
Infection Physical injury Emotional stress Excessive Fatigue Pregnancy Poor state of health Low vitamins intake
Which type of white blood cells is thought to be connected to Multiple Sclerosis
T-Cells
Which type of cells of the brain is thought to be attacked in MS ?
Oligodendrocyte
Types of Multiple Sclerosis
Relapsing remitting 85%
Primary progressive 10%
Secondary progressive 5%
Clinically isolated syndrome 5%
What’s the definition of Relapsing remitting Multiple Sclerosis
Each time the patient have a new symptoms lasting for at least 2 days
After being stable for 30 days at least
In head MRI for Multiple Sclerosis what do you expect to see
Multiple Sclerosis Plague
What are the best examinations for Multiple Sclerosis
MRI
LP
Visual evoked potation
In LP for Multiple Sclerosis what do you expect to see
Oligoclonal bands formed of IgG indicating immune activation
Management of Multiple Sclerosis doing attack
High-dose corticosteroids
IV IgG
Plasmapharesis
Management of Multiple Sclerosis between attacks
Interferon beta
Glatiramer acetate
Natalizumab
Fingolimod