Multiple Sclerosis Flashcards

1
Q

Definition of Multiple Sclerosis

A

Inflammatory disorder of an unknown cause affecting CNS characterised by demyelination and scarring

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2
Q

Incriminating factors of Multiple Sclerosis

A

Infection (viral)
Autoimmune
Genetic susceptibility

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3
Q

Precipitating factors of Multiple Sclerosis

A
Infection
Physical injury
Emotional stress
Excessive Fatigue
Pregnancy
Poor state of health
Low vitamins intake
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4
Q

Which type of white blood cells is thought to be connected to Multiple Sclerosis

A

T-Cells

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5
Q

Which type of cells of the brain is thought to be attacked in MS ?

A

Oligodendrocyte

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6
Q

Types of Multiple Sclerosis

A

Relapsing remitting 85%
Primary progressive 10%
Secondary progressive 5%

Clinically isolated syndrome 5%

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7
Q

What’s the definition of Relapsing remitting Multiple Sclerosis

A

Each time the patient have a new symptoms lasting for at least 2 days

After being stable for 30 days at least

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8
Q

In head MRI for Multiple Sclerosis what do you expect to see

A

Multiple Sclerosis Plague

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9
Q

What are the best examinations for Multiple Sclerosis

A

MRI
LP
Visual evoked potation

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10
Q

In LP for Multiple Sclerosis what do you expect to see

A

Oligoclonal bands formed of IgG indicating immune activation

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11
Q

Management of Multiple Sclerosis doing attack

A

High-dose corticosteroids
IV IgG
Plasmapharesis

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12
Q

Management of Multiple Sclerosis between attacks

A

Interferon beta
Glatiramer acetate
Natalizumab
Fingolimod

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