Multiple Pregnancy and Birth Flashcards
What increases the chance of multiple pregnancy
Maternal Age
High Parity
Family History
PCOS
Ethnicity
Assisted reproduction
Does the rate of multiple birth increase by maternal age
Yes (ONS, 2023)
A steady increase until 40-45 and then a spike at >45
(See Flashcard)
What campaign did HFEA launch in 2007 and what was the aim of this?
The collaborative ‘One at a time’ campaign in 2007 to reduce high multiple births from IVF in the UK.
According to HFEA, 2022 how has the average UK multiple birth rate from IVF treatment changed?
Has decreased from around 28% in the 1990s to 6% in 2019.
What are the characteristics of monozygotic twins?
Identical twins
From one oocyte and spermatozoon that splits into two after fertilisation
1/3 of all twins
Non-hereditary
What are the characteristics of Dizygotic twins?
Non-identical twins
Two separate oocytes that are fertilised by two separate spermatozoa
2/3 of all twins
Hereditary
What is the difference between the chorion and amnion?
Chorion- The outer membrane
Amnion-Inner membrane
See photo
What does Dichorionic mean?
Two placentae (may be fused)
Two chorions
Two amnions
These twins can either be dizygotic or monozygotic
What does monochorionic mean?
One placenta
One chorion
Two amnions (One amnion in monoamniotic twins is very rare)
These twns can only be monozygotic.
What is meant by dichorionic diamniotic by Brewester and Turier, 2020
Most common- 2/3 of twin pregnancies
Both babies have there own placenta
2 chorion 2 amnion
Usually non-identical- can occasionally be identical
Diagnosed by presence of lambda sign on scan (see photo)
Chronicity and amnioicity determined at dating scan (if not, needs to be determined by 14 weeks)
Why dos chorionicity and amnioicity need to be determined at dating scan or by 14 weeks?
Differences between two types of placentation are more pronounced in first trimester.
What are monochorionic twins according to Brewster and Turier, 2020?
usually Monochorionic Diamniotic (MCDA)
Monochorionic Monoamniotic (MCMA) rare about 8:100,000
Always Identical
MC twin pregnancies have a higher risk of complications in pregnancy; perinatal morbidity and mortality
If unable to tell on USS, treat as monochorionic until proven otherwise.
What are Trichorionic triaminotic triplets?
Each baby has a separate placenta and amniotic sac.
What are Dichorionic triamniotic triplets
One baby has a separate placenta and 2 baby’s share a placenta.
All 3 babies have a separate amniotic sacs.
What are Dichorionic Diamniotic triplets
One baby has a separate placenta and amniotic sac
Two of the babies share a placenta and amniotic sac.
What are Monochorionic triamniotic triplets?
All 3 babies share a placenta
All 3 babies have separate amniotic sacs
What are Monochorionic Diamniotic triplets
All 3 babies share 1 placenta
One baby has a separate amniotic sac and two babies share 1 sac
What are Monochorionic monoamniotic triplets?
All 3 babies share a placenta and amniotic sac.
What is the management of care for multiple pregnancies according to NICE 2024 guidelines?
Consultant led care- Core team of specialist obstetricians, specialist midwives and monographers, all of whom have knowledge of managing twin/triplet pregnancies.
Co-ordinate care to:
Minimise number of hospital visits
Provide care as close to home as possible
Provide continuity of care within and between hospitals and the community.
What is the schedule of care from DCDA twins according to NICE, 2024 guidelines?
At least 8 AN appts with a healthcare professional from the core
professional team:
○ At least 2 of these appointments should be with the specialist obstetrician
● Scans and appointments - dating scan then 4 weekly between 20 and 36
weeks
● Offer additional appointments without scans at 16 and 34 weeks
what is the schedule of care for MCDA (NICE, 2024)
At least 11 AN appts with a healthcare professional from the core
professional team
○ At least 2 of these appointments should be with the specialist obstetrician
● 2 weekly scans between 16 and 34 weeks
● All scans performed by fetal medicine consultant
What is the schedule of care for TCTA (NICE, 2024)
At least 9 AN appts with a healthcare professional from the core
professional team
○ At least 2 of these appointments should be with the specialist obstetrician
● Scans and appointments - dating scan, 20, 24 then 2 weekly until 34 weeks
● Offer an additional appointment without a scan at 16 weeks
what is the schedule of care for DCTA or MCTA (NICE, 2024)
At least 11 AN appts with a healthcare professional from the core
professional team
○ At least 5 of these appointments should be with the specialist obstetrician
● 2 weekly scans between 16 and 34 weeks
Schedule of care for MA triplets (NICE, 2024)
Offer women with a twin or triplet pregnancy involving a shared amnion
individualised care from a consultant in a tertiary level fetal medicine centre