Multiple Dose Regimens

Question 1

What are the two main parameter that can be adjusted in developing a dosage regimen?

Answer 1

Dose size and dosing freqency

Question 2

When will a plateau be reached when given multiple doses?

Answer 2

3 to 5 half lives
it is independent of dose
if drug is stopped, most drugs will be eliminated in 3-5 half lives assuming kinetics doesn’t change.