Multiple Choice: Molecular Genatics Flashcards
Structure of DNA
Made up of subunits called nucleotides containing a deoxyribose sugar, phosphate group and nitrogenous bases
Nitrogenous base: Adenine & Thymine, Guanine & and Cytosine
Structure of RNA
Made up of subunits called nucleotides containing a deoxyribose sugar, phosphate group and nitrogenous bases
Nitrogenous base: Adenine & Uracil, Guanine & and Cytosine
Central Dogma
The fundamental principle of molecular genetics, which states that genetic information flows from DNA to RNA to proteins.
Chargaffs Rules
Idea of Complementary base pairing
purine and pyrimidine base pairs are linked to each other.
A&T/U , G&C
The symmetry is key to the structure of DNA and its ability to divide itself accurately and convey genetic information.
Complimentary base pairing
A&T, A&U, G&C
Mutation types (Pg. 341 Textbook)
Point: a change in a single nucleotide in a gene through substitution, insertion and deletion
Missense: change in a single amino acid
nonsense: a change results in a premature stop codon.
silent: change does not affect the functioning of the gene.
frameshift: one or more nucleotides are inserted into are deleted causing a shift.
recognition sites for restriction enzymes
located on dna molecules contains 4-8 base pairs sequences