Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm Exam 2 > Multimodal Pain Control > Flashcards

Multimodal Pain Control Flashcards

1
Q

at what temp does the pt have to be to be considered a payable event

A

at least 36 degrees celsius

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

two components of multimodal anes

A

short acting anesthetic agent and opioid sparing techniques

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

gabapentin is a structural analog of

A

gaba

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

gabapentin binds to

A

vg ca channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

moa of gabapentin

A

inhibition of excitatory nt release and inhibition of descending pain pathways

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

gabapentin has no

A

drug interactions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

gabapentin can be used to treat

A

partial seizures and chronic pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

dose of gabapentin for preemptive analgesia

A

300-1200 mg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

relative contraindications to gabapentin

A

myasthenia gravis and myoclonus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

s/e of gabapentin

A

abrupt withdrawal in sz patients will cause seizures; pt becomes more somnolent and fatigued

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

COX catalyzes synthesis of

A

prostaglandin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

COX1 is needed to

A

maintain homeostasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

many of the symptoms associated with used of nsaids is d/t blocking of

A

COX1 pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

COX2 is an _______ form of pain

A

inducible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

_____ inhibition of COX2 helps modulate pain

A

central

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

COX2 selective inhibitors have this advantage over nonselectives; what disadvantage?

A

does not block physiologic processes; possible MI and CVA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

nsaid dosage ceiling

A

does not increase positive effects if you take more, but will increase negative effects

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

first COX2 selective inhibitor

A

celebrex or celecoxib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

celebrex peaks at

A

3 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

acetaminophen does not share this property with nsaids

A

anti inflammatory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

peak po dose of tylenol

A

1-3 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

peak iv dose of tylenol

A

30 mins-1 hour

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

main moa of tylenol

A

reduces prostaglandin metabolite

24
Q

duration of tylenol

A

6-8 hours

25
Q

ketorolac moa

A

non specific nsaid; inhibits PG synthesis

26
Q

relative CI for ketorolac

A

cad, cabg, bleeding, renal impairment

27
Q

ketorolac peak

A

45-60 mins

28
Q

ketorolac is a potent analgesic but a moderate

A

anti inflammatory

29
Q

ketorolac has no effect on the

A

biliary tract

30
Q

ibuprofen moa

A

non selective cox inhibitor

31
Q

relative c/t to ibuprofen

A

nsaid allergy, cabg, bleeding

32
Q

ibuprofen peak

A

1-2 hours

33
Q

ibuprofen is excreted in the

A

urine and bile

34
Q

name two short acting anesthetic agents

A

ketamine and propofol

35
Q

lidocaine somehow helps with

A

chronic pain

36
Q

build up of lidocaine can occur with

A

liver and renal impairment

37
Q

safe plasma concentration of lidocain

A

<5 mcg/mL

38
Q

we start seeing sz/unconsciousness at what plasma concentration of lidocain

A

10-15 mcg/mL

39
Q

nmda stands for

A

n methyl d aspartate

40
Q

magnesium is an _____ blocker

A

nmda receptor

41
Q

probable moa of mg for pain

A

potentiation of opioids centrally and peripherally

42
Q

Mg regulates

A

ca access into cell, neurotransmission, cell signaling, enzyme function; tldr, hyperpolarizes the cell to decrease excitability

43
Q

relative c/i to Mg

A

myasthenia gravis, renal failure

44
Q

Mg s/e

A

bradycardia, hpn, diarrhea

45
Q

mg will decrease ______ dose intraoperatively

A

fentanyl

46
Q

s/e of zofran

A

HA, constipation, qt prolongation

47
Q

e 1/2 of zofran

A

4 hours

48
Q

give zofran when

A

towards the end of the case

49
Q

what place in the brain has glucocorticoid receptors

A

nts

50
Q

decadron enhances the effects of

A

5ht3 antagonists and droperidol

51
Q

moa of decadron

A

anti inflammatory; inhibition of phospholipase and cytokines; cell stabilization

52
Q

delay of onset of decardron

A

2 hours

53
Q

max dose of tylenol

A

3000-4000 mg

54
Q

max dose of ibuprofen

A

3200 mg

55
Q

max dose of ketorolac

A

120 mg

56
Q

sofa stands for

A

society of opioid free anesthesia

Pharm Exam 2 (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions