Mucosal Administration Flashcards
1
Q
What are the potential targets for lung diseases?
A
Aveolar macrophages
Epithelial cells
2
Q
What is the optimal size for drugs for for lung administration?
A
1-5 micrometers
3
Q
What nanoparticles used in pulmonary drug delivery?
A
- Liposomes
- Polymeric nanoparticles
- Solid lipid nanoparticles
- Protein nanoparticles
4
Q
What 3 main properties for passive targeting for pulmonary drug delivery do we act upon?
A
Size
Charge
Surface properties
5
Q
What cells in the lung can you actively target?
A
Alveolar macrophages
Bronchial epithelial
6
Q
What receptors on alveolar macrophages can you target?
A
Mannose
