MTB 5 Flashcards
Normal gap Metabolic Acidosis with positive UAG
RTA
Normal gap Metabolic Acidosis with negative UAG
Diarrhea
- kidney’s ability to excrete acid intact
Causes of Metabolic Acidosis - Normal AG
RTA
Diarrhea
Causes of Metabolic Acidosis - Increased AG
MUDPILES Methanol toxicity Uremia DKA Phenytoin, Paraldehyde INH Ethylene glycol Salicylates
ABG in Metabolic Acidosis
All low
Low pH, pCO2, HCO3
Causes of Metabolic Alkalosis
GI loss - vomiting, NG tube Increased aldosterone Diuretics Milk-alkali syndrome - hi volume liquid antacids Hypokalema
ABG in Metabolic Alkalosis
All high
High pH > 7.40
High HCO3
High pCO2
What are the 2 phases of Vomiting?
- Generation phase - loss of gastric fluids (HCl, etc) causes retention of H2O and HCO3. Loss of gastric acid - no stimulus for pancreas to secrete HCO3, so HCO3 is retained in blood = Metabolic Alkalosis
- Maintainance phase - volume loss causes ECV to go down, decreased renal perfusion so kidneys activate RAAS. Aldosterone retains H2O, loss of H+ and K+ to get Hypokalemia and contraction alkalosis
TX for Vomiting
IVF
NS
This will tx contraction alkalosis
Equation for minute ventilation
Minute ventilation = RR x TV
Respiratory Alkalosis
pCO2?
Minute ventilation?
Low pCO2
Minute Vent =Increased
Causes of Respiratory Alkalosis
Anemia Anxiety Pain Fever Interstitial Lung Dz Pulmonary Emboli
Respiratory Acidosis
pCO2?
Minute ventilation?
High pCO2
Minute vent = Decreased
Causes of Respiratory Acidosis
COPD/Emphysema Drowning Opiate OD Alpha 1 antitrypsin deficiency Kyphoscoliosis Sleep apnea/morbid obesity
MCC nephrolithiasis
Calcium Oxalate in alkaline urine
MS risk factor for nephrolithiasis
Overexcretion of calcium in urine
Most accurate test for nephrolithiasis
CT scan
- does not need contrast
IVP needs contrast, takes hours
Pt w excruciating pain in left flank radiating to groin presents to ED. Next step?
Ketorolac - NSAID provides pain relief like opiates
Which GI disorder do we see kidney stones?
Crohn dz b/c of increased oxalate absorption
Also, fat malabsorption increases stone formation
When is IVP the right answer in nephrolithiasis
Never
Best initial TX for renal colic
- Analgesics
- Hydration
- Imaging to confirm stone location
- CT/Sonography to detect obstruction, ie hydronephrosis