MTB 4 Flashcards
Presentation of Cardiomyopathy
SOB worsened on exertion
Edema
Rales
JVD
Best initial test for Cardiomyopathy
Echo
Most accurate test for Cardiomyopathy
Echo
TX for Cardiomyopathy
Diuretics
Etiology of Dilated Cardiomyopathy
Previous MI Ischemia (MCC) Alcohol (2nd MCC) Postviral myocarditis Radiation Doxorubicin Chagas
MC Indication for heart transplant
Dilated Cardiomyopathy
TX for Dilated Cardiomyopathy that lowers mortality
ACEi/ARBs
Beta blockers - Metoprolol, Carvedilol
Spironolactone
TX for Dilated Cardiomyopathy to control Sx’s
Digoxin
Diuretics
TX for Dilated Cardiomyopathy if Wide QRS > 120
Biventricular Pacemaker
Hypertrophic Cardiomyopathy Etiology
Presentation
HTN
- Heart hypertrophies to carry excess load but has difficulty relaxing in diastole -> SOB - MC presentation
S4 Gallop
Fewer si’s of RSHF
HOCM Pathophys
Genetic - Chromosome 14
Abnormal septum shape
Asymmetrically hypertrophied septum obstructs bt septum and valve leaflet, blocking blood leaving the heart
What kind of motion is seen in HOCM
SAM - Systolic Anterior Motion
Abnormal MV leaflet motion
Presentation of HOCM
Dyspnea - MC Chest pain Syncope/light headedness Sudden death in athletes Palpable S4 gallop
What increases HR
Exercise
Dehydration
Diuretics
HOCM sx’s are worse with
Increased HR
HOCM worse with
Decreased LV chamber size
- ACEi/ARBs
- Digoxin
- Hydralazine
- Valsalva and standing suddenly
Which population is HOCM more common in
African Americans
Murmur of HOCM
Same as MR
Palpable S4 gallop
Holosystolic obscures S1 and S2
Radiates to axilla
Best initial test HCM and HOCM
Findings
Echo
Septum is 1.5X thickness of posterior wall
TX for HCM and HOCM
- Beta blockers best initial tx
- Negative inotropes - verapamil, disopyramide
- Diuretics HCM ONLY
- CI In HOCM
When do we use implantable defibrillators in HOCM
Any pt with syncope
When do we ablate septum in HOCM
Failure with meds
- Catheter placed absolute alcohol in muscle causing infarctions
- Surgical myomectomy if sx’s persist
EKG findigns in HOCM
Septal Q waves - inferior and lateral leads
Wrong answers for TX for HCM, but used in DCM
Digoxin
Spironolactone
Difference bt HCM and HOCM
ACEi and diuretics do NOT help
Causes of Restrictive Cardiomyopathy
Sarcoidosis Amyloidosis Hemochromatosis Endomyocardial fibrosis Scleroderma
Pathophys of Restrictive Cardiomyopathy
Heart neither contracts nor relaxes normally
Immobility
Presentation of Restrictive Cardiomyopathy
Dyspnea RSHF si/sx's - Ascites - Edema - JVD - HSM
What sign is commonly seen in Restrictive Cardiomyopathy
Kussmaul sign - increase in JVP on inhalation
Best initial test Restrictive Cardiomyopathy
Echo
Most accurate test Restrictive Cardiomyopathy
Endomyocardial BX
TX for Restrictive Cardiomyopathy
Treat underlying cause
Diuretics for Pulm HTN, RSHF si’s
What maneuvers decrease venous return to heart
Standing
Valsalva
What drug has similar effects as Standing and Valsalva
Diuretics
What maneuvers increase venous return to heart
Squatting
Leg raising
What impact does handgrip have on heart
Increases Afterload = Fuller LV = Decreased LV emptying
Arm muscle contraction compresses arteries of UE - Brachial, Radial, & Ulnar. Obstructs ability of blood to empty the heart
MOA Amyl Nitrate
Direct Arteriolar Vasodilator = Increases LV emptying
Like ACEi/ARBs
Emptier LV
Etiology of Pericarditis
Infxn Inflamm Dz Connective tissue Dz Truam Cancer
MC Infxn in Pericarditis
Viral - Coxsackie B
Strep
Staph
Fungal
MC Connective tissue Cause of Pericarditis
Others?
SLE Others: Wegener's Goodpasture RA PAN
Presentation of Uremic Pericarditis
Renal Failure pts
BUN > 60
Diffuse STE NOT seen on EKG
Inflammatory
TX for Uremic Pericarditis
Hemodialysis
Dialysis
EKG findings in Pericarditis
Diffuse, low voltage STE in all leads
PR depression = most specific
Pericardial Friction Rub
Scratching
High-pitched sound
3 parts
Heard best w diaphragm w pt sitting fwd at forced end expiration
TX for Pericarditis
Treat underlying cause
Viral - NSAIDs, Ibu, naproxen, indomethacin
Steroids if no improvement
Is Pericardial Tamponade an emergency
Yes.
Super Emergency
Etiology of Pericardial Tamponade
Causes of pericarditis
Fluid extravasates and compresses chambers
Starts on right side b/c walls are thinner
TX for Pericardial Tamponade
Emergent thoracotomy
Needle pericardiocentesis
Subxiphoid surgical drainage
Presentation of Pericardial Tamponade
HypoTN Tachycardia Distended neck veins Clear lungs Pulsus Paradoxus
How to differentiate bt Pericardial Tamponade and Pulmonary emboli?
Pericardial Tamponade has JVD.
Pulm. Emboli does not.
EKG of Pericardial Tamponade
Electrical alternans - varying heights of QRS complexes
CXR of Pericardial Tamponade
Enlarged cardiac shadow
Globular heart
Echo of Pericardial Tamponade
RA and RV diastolic collapse
Right heart catheterization of Pericardial Tamponade
Equalization of pressures in diastole
TX for Pericardial Tamponade
Pericardiocentesis
IVF
Hole/window placed in pericardium if recurrent