MTB 2 CK - Obstetrics Flashcards
Definition of embryo
Fertilization - 8 weeks
Definition of fetus
8 weeks - birth
Definition of infant
Birth to 1 yo
Developmental age
Number of days since fertilization
Gestational age
Number of days since LMP
Nagele rule
Est day of delivery by taking LMP - 3 mo + 7 d
First trimester def
Fert - 14 w GA
Second trimester def
14 w GA - 26 w GA
Third trimester def
26 w GA - delivery
Previable
Born before 24 w
Preterm
25-37 weeks
Early term
37 - 38.6
Full term
39 - 40.6
Late term
41 - 41.6
Postterm
42 w +
First sign of pregnancy on PE
Goodell sign (softening of cervix at 4 w)
Ladin sign
Softening of midline uterus at 6 w
Chadwick sign
Blue discoloration of vagina and cervix at 6-8 w
Chlosama
Mask of pregnancy on forehead, nose, and cheeks at 16 w
What makes B HCG
Placenta
When does BHCG peak
10 weeks
When should gestational sac be evident
5 w or BHCG of 1000-1500
Cardiology changes in pregnancy
Increased CO
Lower BP
What are GI changes in pregnancy
Morning sickness
GERD
Constipation
What are renal changes in pregnancy
Pyelo from ureter compression
Increased GFR
Decreased BUN/Cr
What are heme changes in pregnancy
Anemia
Hypercoagulability
What to do in first trimester
q4-6 week checks US at 11-14 w (GA, nuchal trans) FHR at end of first tri Blood tests, Pap, GC First tri noninvasive screen
How to confirm GA in first tri
US
What to do in second trimester
Triple or quad at 15-20
FHR
Quickening
US for fetal malformation
What is a triple screen
MSAFP
BHCG
Estriol
What is a quad screen
MSAFP
BHCG
Estriol
Inhibin A
High MSAFP
Dating error
Neural tube defect
Abdominal wall defect
What to do in third trimester
q2-3 w visits until 36 w, qweekly >36 At 37 w, examine cervix qvisit 27 w CBC 24-28 w glucose load 36 week repeat GC, do GBS
What is glucose load test
Give 50 g glucose and check after 1 hr
What is glucose tolerance test
Get fasting glucose
Give 100 g glucose
Check at 1, 2, 3 hours
(Elevation at any 2 is GDM)
How to interpret 3rd tri CBC
If hgb
When to get glucose tolerance test
If load >140 at 1 h
What is chorionic villus sampling
10-13 week for fetal karyotype
What is amnio
11-14 week for fetal karyotype
What is fetal blood sampling
Perc umb blood sample for Rh isoimm
Most common site of ectopic pregnancy
Ampulla
Risk factors for ectopic pregnancy
PID
IUD
Previous ectopic
Pres ectopic pregnancy
Unilateral pelvic pain
Vaginal bleeding
Hypotx if ruptured
How to dx ectopic
BHCG
US
Laparoscopy
Tx ectopic preg
If HDUS, IVF and immediate surgery
If stable, CBC, type and screen, LFTs, BHCG then methotrexate
How to follow medical treatment of ectopic pregnancy
Follow BHCG for 15% decrease in 4-7 d
If none, second dose methotrexate
If not decreasing after second dose, surgery
Who shouldn’t get methotrexate
Immunodeficiency Noncompliant Liver dz >3,5 cm ectopic Fetal heartbeat can be heard
Sfx methotrexate
Hepatotox
Surgery in ectopic
Salpinostomy (preserves tube)
Salpingectomy (no preservation)
Definition of abortion
Pregnancy that ends before 20 weeks
Cause of abortions
Csomal abnormalities >>> Anatomic abnormalities STDs Immunological factors (APL) Endocrine factors Malnutrition Trauma Rh isoimm
Pres abortion
Crampy pain
Vaginal bleeding
How to dx abortion
CBC
Blood type and Rh screen
US
Complete abortion
No products of conception
Office f/u
Incomplete abortion
Some products of conception
D&C, medical
Inevitable abortion
Products of conception intact but IU bleeding and cervical diln
D&C, medical
Threatened abortion
Products of conception intact but IU bleeding
Bed rest
Missed abortion
Death of fetus with products in uterus
D&C, medical
Septic abortion
Infection of uterus and surrounding area
D&C and IV Abx
Medical treatment of abortion
Misoprostol
Who should receive Rhogam
Rh negative moms that have trauma
First clue for multiple gestations
High BHCG and MSAFP
Complications of multiple gestations
Spontaneous abortion of one
Premature L&D
Placenta previa
Anemia
Risk factors for premature labor
PROM Multiple gestations Previous preterm labor Placental abruption Uterine abnls Infx PreE Intrabdominal surgery
When should premature labor not be stopped with tocolysis
Severe HTN Cardiac dz Diln >4 cm Maternal hemorrhage Fetal death Chorio
What are some tocolytics
Mag sulfate
CCB
Terbutaline
Sfx mag
Flushing
HA
Diplopia
Fatigue
Sfx CCB
HA
Flushing
Dizzy
Sfx terb
Palps
Hypotx
Monitor mag
DTRs frequently
How to confirm amniotic fluid
Pool
Nitrazine paper = blue
Fern
WHat is PPROM
Early and >24 h
Complications of PROM
Preterm labor
Cord prolapse
Abruption
Chorio
Manage PROM
Chorio = deliver
No chorio, at term = wait 6-12 h for spont delivery, then induce
Preterm = steroids, tocolytics, ampicillin and azithro x 1 (cefazolin or clinda if allergic)
What increases the risk of placenta previa
Previous C sections
Previous uterine surgery
Multiple gest
Previous previa
First step in third tri bleeding
TRANSABDOMINAL US (DO NOT DO DIGITAL VAGINAL EXAM OR TRANSVAGINAL US)
Pres of placenta previa
Painless vaginal bldg
When to tx previa
Large volume bldg
Drop hct
How to tx previa
Strict pelvic rest
When to deliver in previa
> 4 cm diln
Severe hemorrhage
Fetal distress
Risk factors for abruption
HTN Prior abruption Cocaine External trauma Smoking
Pres of abruption
Third tri bleeding
Severe pain
Ctx
Possible fetal distress
Complications of concealed abruption
DIC
Uterine tetany
Fetal hypoxia, death
Sheehan
Do C section in abruption with
Uncontrolled hemorrhage
Rapidly expanding concealed hem
Fetal distress
Rapid separation
Do vaginal delivery in abruption with
Limited separation
Reassuring FHR
Extensive separation with dead fetus
Risk factors for uterine rupture
C section Trauma Myomectomy Polyhydramnios Multiple gestations Placenta percreta
Pres of uterine rupture
Extreme abdominal pain
Abnl bump in abdomen
No ctx
Regression of fetus (moving away from vagina)
Tx uterine rupture
Immediate LAPAROTOMY
Cause of Rh incompatibility
Rh negative mom with Rh positive baby
How to screen for Rh incompatibility
If Rh negative, check antibody titer for sensitization
What does Rh incompatibility cause
Hemolytic dz of newborn
What is hemolytic dz of newborn
Fetal anemia
Extramedullary prodn of RBCs (HSM)
High hgb and bilirubin
Erythroblastosis fetalis (CHF)
How to manage Rh incomp
If unsensitized, give Rhogam at 28 weeks and at delivery if baby is positive
If sensitized, get titer, if >1:16, serial amnio for bili
If high bili, do IU transfusion
Chronic HTN in preg
> 140/90 before 20 week GA
How to tx chronic HTN in preg
Methyldopa
Labetalol
Nifedipine
Gest HTN in preg
> 140/90 after 20 week GA with no proteinuria or edema
Risk factors for preE
Chronic HTN
Renal dz
Difference btwn mild and severe preE
140/90 vs 160/110 1-2+ (300mg) vs 3-4+ (5g) Facial, hand, feet edema vs generalized Normal mental status vs changes No vision changes vs yes No LFT changes vs yes
What is eclampsia
TC seizure in preE
Manage mild preE
Deliver if at term
BMZ and Mag if preterm
Manage severe preE
Deliver if at term
Mag and hydralazine if preterm to stabilize, BMZ and mag if can’t stabilize
What is HELLP
Hemolysis
Elevated liver enzymes
Low platelets
Comps of pregestational DM
PreE Spont abt Increased infx Increased postpartum hem More congenital problems Macrosomia/dystocia Preterm labor
Addl tests to do in pregest DM
EKG
24 h Cr
A1C
Optho exam
Fetal testing needed in pregest DM
32-36 w: Weekly NST and US
>36 w: Weekly NST, BPP
37 w: L/S ratio
What is the definition of IUGR
Weight in the bottom 10%
What does symmetric IUGR baby look like
Brain in proportion with rest of body
When does symmetric IUGR occur
Before 20 w
What does asymmetric IUGR baby look like
Brain weight is not decreased (big head)
When does asymmetric IUGR occur
After 20 w
What are causes of IUGR
Chromosomal abnormalities Neural tube Infx Multiple gestation Renal dz
Complications of IUGR
Premature labor Stillbirth Fetal hypoxia Low IQ Seizures MR
What is the definition of macrosomia
4500 g
Risk factors for macrosomia
Maternal DM
Maternal obesity
Postterm pregnancy
When to do an US for larger than expected fundal height
> 3 cm
Complications of macrosomia
Dystocia
Birth injuries
Low Apgars
Hypoglycemia
How to manage macrosomia
If lungs are mature, IOL before 4500g
If >4500g, C section
What is a reactive NST
2 fetal movements
Acceleration >15 bpm lasting 15-20 seconds within 20 mins
What to do if NST is nonreactive
VIbroacoustic stimulation
What is BPP
NS Fetal chest expansion (1x in 30 min) Fetal movement (>3 in 30 mins) Flexion of an extremity AFI
What is normal BPP
> 8
What is normal fetal HR
110-160
What is fetal bradycardia
What is fetal tachycardia
> 160
Cause of early decels
Head compressions
Cause of variables
Cord compression
Cause of late decels
Hypoxia
What is lightening
Fetal descent to pelvic brim
What is bloody show
Bloody mucus released with cervical effacement
How long should phase 1 last
Primip: 6-18
Multip: 2-10
How long should latent phase last
6-7, 4-5
How long should active phase last
1 cm/h
1.2 cm/h
How long should stage 2 last
30 min - 3 h
5-30 min
How long should stage 3 last
30 min
Signs of placenta separation
Fresh vaginal bleeding
Umb cord lengthening
Uterine fundus rising
Uterus becoming firm
Meds for IOL
Prostaglandin E2 for cervical ripening
Oxytocin
Who to avoid prostaglandin E2 in
Asthma
What defines arrest of cervical dilation
No dilation for >2 h
What defines a prolonged latent stage
> 20 h for primip
>14 h for multip
What causes prolonged latent stage
Sedn
Unfavorable cervix
Uterine dysfx with irreg/weak ctx
Tx prolonged latent stage
Rest and hydration
What defines protracted cervical dilation
Causes of protracted cervical diln
Power
Passenger
Passage
Tx protracted cervical diln
C section or oxytocin
What is arrest of fetal descent
No descent for 1 h
What causes arrest disorders
Cephalopelvic disproportion
Malpresentation
Excessive sedn/anesthesia
First step in presumed breech
US
What are Leopold manuevers
Estimate fetal wt and presenting parts
What is frank breech
Hips are flexed with extended kneew
What is complete breech
Hips and knees are flexed
What is footling breech
Feet first
When can you perform cephalic version
After 36 weeks
Steps of tx shoulder dystocia
McRoberts (flexion of knees, suprapubic pressure)
Rubin (push posterior shoulder toward fetal head)
Woods (push posterior shoulder toward fetal back)
Deliver posterior arm
Fracture clavicle
Zavanelli (push head back in)
What defines PPH
> 500 ml
What defines early vs late PPH
24 h
Risk factors for atony
Anesthesia Uterine overdistension Prolonged labor Lac Retained placenta Coagulopathy
Tx PPH
Bimanual exam for rupture, retained placental
If normal, bimanual compression and massage
Oxytocin