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Infectious > MTB 2 > Flashcards

MTB 2 Flashcards

1
Q

Most appropriate next step in pt w influenza and w/in 48 hrs

A

Nasopharyngeal swab or wash - Ag detection

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2
Q

Who should get annual influenza vaccine

A

> 50
Health care workers
Preg - 2nd/3rd
Annual

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3
Q

Most common causes of bloody diarrhea

A

Salmonella

Campylobacter

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4
Q

Presentation of E.coli 0157

A

HUS
Hemolysis
Increased Cr
Low platelets

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5
Q

Bloody diarrhea + Hx of liver dz

A

Vibrio vulnificus

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6
Q

Bloody diarrhea + hemochromatosis or blood trasfusions

A

Yersinia - high affinity for Iron

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7
Q

Best initial test in bloody diarrhea

A

Blood and/or fecal leukocytes

Lactoferrin = better choice

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8
Q

Most accurate test in bloody diarrhea

A

Stool culture

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9
Q

DDX for diarrhea w no blood or WBCs in stool

A
  1. Viral
  2. Giardia
  3. Cryptosporidiosis
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10
Q

Preformed toxins ass’d with vomiting

A

Bacillus

Staph

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11
Q

Scrombid Infxn

A

Rapid onset
Flushing, wheezing, rash
Fish - decayed
Tx: Antihistamines

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12
Q

TX for infectious diarrhea

A

Mild: Oral fluids
Severe: fluids + Cipro

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13
Q

Labs elevated in hepatitis

A

Direct BR
AP
ALT:AST

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14
Q

High PT in hepatitis

A

Risk for Fulminant hepatic failure

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15
Q

Best initial test hepatitis

A

IgM Ab for acute infxn

IgG Ab for resolution

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16
Q

Test for dz activity in HCV

A

PCR for RNA level

= viral replication

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17
Q

Serologic findings Acute or Chronic HBV Infxn

A

HBsAg +
HBeAg +
HBcAb IgM or IgG +
HBsAb -

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18
Q

Serologic finding Resolved/old Infxn HBV

A

HBsAg -
HBeAg -
HBcAb IgG +
HBsAb +

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19
Q

Serologic finding Vaccination HBV

A

HBsAg -
HBeAg -
HBcAb IgG -
HBsAb +

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20
Q

Serologic finding Window Period

A

HBsAg -
HBeAg -
HBcAb IgM + THen HBcAb IgG +
HBsAb -

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21
Q

What does HBsAg measure

A

Active Viral Particles

22
Q

Which HBV marker correlates w the amt or quantity of active viral replication

A

HBeAg

E antigen is correlated to DNA Polymerase

23
Q

Which HBV marker indicates that active infxn has resolved and is no longer transmissable

A

HBsAg - as long as present, still some viral replication occurring
Transmissability ceases when DNA polymerase ceases

24
Q

Which HBV marker is the best indication for need for tx w antiviral meds?

A

HBeAg = strongest indicator of active viral replication

25
Q

Which HBV marker is best indicator that pregnant woman will transmit infxn to her child

A

HBeAg

26
Q

AEs of IFN

A 
Arthralgia/myalgia
Leukopenia 
Thrombocytopenia
Depression
Flu-like Sx's
27
Q

What is the goal of chronic hepatitis therapy

A
  1. Reduce DNA Polymerase to undetectable levels

2. Convert pts w e-Antigen to e-Antibodies

28
Q

Tx for HBV

A

Tenofovir - blocks DNA polymerase the most
Enteavir
Adefovir

29
Q

When are Hep C pts treated and with what

Goal?

A

If PCR-RNA is elevated
IFN and Ribavarin
Goal = undetedtable viral load

30
Q

AE of Ribavarin

A

Anemia

31
Q

Best initial test for urethritis

A

Urethral swab for Gram stain

32
Q

WU for urethritis

A
  1. Swab
  2. Culture
  3. Treat
33
Q

Most accurate test for urethritis

A

Urethral culture
DNA Probe
Nucleic acid amplification test

34
Q

TX for urethritis

A

Ceftriaxone/cefixime
+
Azithromycin/Doxycycline

35
Q

Presentation of Urethritis

A

Dysuria
Urinary Frequency
Burning

36
Q

Presentation of Cervicitis

A

Cervical Discharge

Inflamed strawberry cervix

37
Q

Most accurate test for PID

A

Laparoscopy

38
Q

PID TX Inpatient

A

Cefoxitin/Cefotetan
+
Doxycycline

39
Q

PID TX Outpatient

A

Ceftriaxone

Doxycycline

40
Q

PID TX pts w anaphylaxis with PCN

A

Outpatient - Levofloxacin + Metronidazole

Inpatient - Clindamycin + Gentamicin

41
Q

Presentation of herpetic whitlow

TX

A

Viral Infxn of hand
Throbbing pain -> swollen, soft, tender
Self limiting
Health care workers

42
Q

Ulcerative genital dz with:

Painless ulcer, painless nodes

A

Syphilis

43
Q

Ulcerative genital dz with:

Painful ulcer

A

Chancroid - H. ducreyi

44
Q

Ulcerative genital dz with:

LNs tender and suppurating

A

Lymphogranuloma venereum

45
Q

Ulcerative genital dz with:

Vesicles prior to ulcer and Painful

A

HSV

46
Q

Dx test for syphilis

A

Dark field microscopy
VDRL or RPR
FTA or MHA-TP to confirm

47
Q

DX test for Chancroid

A

Stain/culture specialized media

48
Q

DX test for Lymphogranuloma venereum

A

Complement fixation titers in blood

Nucleic acid amplification

49
Q

Most accurate test for HSV

A

Viral culture

50
Q

Syphilis TX

A

Pen G

Doxycycline if allergic

51
Q

TX for chancroid

A

Azithromycin

52
Q

TX for lymphogranuloma venerum

A

Doxycycline

Infectious (4 decks)

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