MTB 1

Question 1

Best initial test for Breast Cancer

Answer 1

FNA BX

Question 2

Breast cancer findings on PE

Answer 2

Hard to touch
Retraction of nipple
Painless

Question 3

How to test for estrogen/progesterone/HER2/neu receptors?

Answer 3

Core needle Bx - more deforming

Question 4

Most accurate Dx test for breast cancer

Answer 4

Open BX - frozen section in OR w immediate resection

Question 5

When do we screen w mammography?

Answer 5

Start at 50 yoa

Question 6

When do we do US in breast cancer

Answer 6

Indeterminant mass lesions
Painful
Varies w menstruation
- US tells cysts v solid lesions

Question 7

When do we do PET in breast cancer

Answer 7

To determine content of LNs not accessible by Bx

Question 8

How does cancer present on PET

Answer 8

Cancer increases uptake on PET

Question 9

BRCA ass’d with?

Answer 9

Breast ca

Ovarian ca

Question 10

When do we Bx Sentinel Node

Answer 10

Routinely in all pts when lumpectomy or masectomy is done

Question 11

When is ER and PR testing done

Answer 11

Routinely in all pts

Question 12

Why is radiation important in breast cancer TX

Answer 12

Indispensible in preventing recurrences

Question 13

What AEs do aromatase inhibitors cause

Answer 13

Osteoporosis

Question 14

Trastuzumab
MOA
Benefit

Answer 14

Anti-Her2/neu Abs

Decreases risk of recurrent dz

Question 15

When do we do adjuvant chemo in breast cancer

Answer 15

Lesions > 1cm

Positive axillary LN

Question 16

DOC when multiple first degree relatives w breast cancer and why

Answer 16

Tamoxifen

Lowers risk of breast cancer

Question 17

Best initial test Prostate Cancer

Answer 17

BX

Question 18

Most accurate test Prostate Cancer

Answer 18

BX

Question 19

TX for Prostate Cancer

Answer 19

Surgery - prostatectomy

Question 20

AEs of Prostatecomy

Answer 20

ED

Urinary Incontinence

Question 21

What does Gleason Grading measure

Answer 21

Aggressiveness

Malignant potential

Question 22

Management that is WRONG in prostate cancer

Answer 22

Screening imaging
Lumpectomy
Chemo

Question 23

High PSA + Palpable mass = next step?

Answer 23

BX the mass

Question 24

High PSA + No Palpable mass = next step?

Answer 24

Transrectal US

• if Mass seen = BX
• if no mass seen = multiple blind BX’s

Question 25

When do we not do surgery in Lung Cancer

Answer 25

Bilateral
Malignant pleural effusion
Heart, Carina, Aorta, Vena Cava involved

Question 26

Which cancer is unresectable in 95%

Answer 26

Small cell - mets outside lung

Question 27

What kind of cancer is Lip cancer?
Causes
Presentation

Answer 27

SQCC - invasive cords of squamous cells w keratin pearls
Sun exposure
Vermillion zone of lower lip
non-healing

Question 28

Ovarian Cancer presentation

Answer 28

Woman > 50 yoa
Increasing abdominal girth
Weight loss

Question 29

Ovarian Cancer
Initial test
Accurate test

Answer 29

Initial Test: US or CT

Accurate: Bx

Question 30

Tx for Ovarian Cancer

Answer 30

Resection - all visible tumor and pelvic organs

Chemo

Question 31

Presentation of Testicular Cancer

Answer 31

Painless Lump in scrotum

Does NOT transilluminate

Question 32

Test for Testicular Cancer

Answer 32

Remove whole testicle w inguinal orchiectomy

Never needle Bx

Question 33

Which testicular cancers secrete AFP

Answer 33

Nonseminomatous cancers

Question 34

TX for Testicular Cancer

Answer 34

1. Orchiectomy
2. Radiation for Local
   Chemo for widespread

Question 35

How does Testicular Cancer Metastasize

Answer 35

Thru Lymphatics in retroperitoneum and moves into chest

Question 36

What is TX for Brain mets w solitary lesion

Answer 36

Surgical resection + Whole brain Radiation

Question 37

What is TX for Brain mets w multiple lesions

Answer 37

Palliative
Whole Brain Radiation
Glucocorticoids

Question 38

Management of Advanced cervical cancer

Answer 38

Hysterectomy