MTAP REVIEW Flashcards
continuous, regulated, process of (self) renewal, proliferation, differentiation, and maturation of all blood cell lines from the bone marrow into the circulation
Hematopoiesis
where hematopoiesis occurs
Organs of the reticuloendothelial system (RES)
- bone marrow, spleen, liver, thymus, lymph nodes
excess production of cells undergo ______.
apoptosis
Ex: Colony-forming unit erythroid
In adults, majority of hematopoiesis occurs in _____.
bone marrow
Extramedullary hematopoiesis occurs in the ______.
spleen, liver
happens when bone marrow is incapable of supplying HSC
responsible for T-cell production
thymus
primary lymphoid organ
bone marrow; thymus
secondary lymphoid organs
lymph nodes, spleen, mucosa-associated lymphoid tissue
Antigen-independent:
(Primary/Secondary) Lymphoid organ
Primary
the cell matures to be a T-cell or B-cell; cells are only capable of differentiating self from non-self
Antigen-dependent:
Primary/Secondary Lymphoid organ
Secondary
exposure to foreign antigens took place
B-cell development happens in the ________.
bone marrow
The B cells that proliferate as memory cell and plasma cells for production of antibodies are referred to as:
Effector B-cell
T/F:
T-cell development starts in the bone marrow
TRUE
Considered double negative (CD4- , CD8-)
and will then migrate into thymus and turn double positive (CD4+ , CD8+)
T/F:
Thymus decreases in size as you age.
TRUE
CD4 are what type of cells
T-helper cells (MHC Class II)
