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IMMUNOLOGY & SEROLOGY > MTAP FINALS > Flashcards

MTAP FINALS Flashcards

1
Q

It’s used for detection of specific infectious agent

A

Immunology and Serology

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2
Q

Defective immune response/system

A

Autoimmune disorder

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3
Q

Pertains to the variable region of the antibody

A

Idiotype

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4
Q

Lyse on the heavy chain structure immunoglobulins

A

Isotype

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5
Q

Sequence in the constant region

A

Allotype

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6
Q

It has 2 different chain

A

Light Chain

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7
Q

It has 22 chromosome

A

Lambda

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8
Q

Found between CH1 and CH2

A

Hinge Region

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9
Q

MHC means

A

Major Histocompatibility Complex

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10
Q

Dictated by several factors. Where antibody producing capability of the antigen when it is present .

A

Immunogenicity

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11
Q

It considered as a rich source of antigen

A

Graft Types

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12
Q

Self antigen that belongs to the host.

A

Autoantigen

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13
Q

Derived from individual’s body/ patient’s own body

A

Autograft

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14
Q

It’s responsible for the molecular weight of antigen

A

Carrier portion

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15
Q

Stable, the best and strongest antigen

A

Protein

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16
Q

Most common carrier is Albumin

A

Hapten

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17
Q

It can induce an immune response

A

Immunogen

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18
Q

It enhance the immune response; to have a greater immune reactivity

A

Adjuvants

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19
Q

Induces the hypersensitivity reactions

A

Allergen

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20
Q

The immune response is exaggerated that can be harmful to individual

A

Hypersensitivity

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21
Q

It must be recognized as foreign or non-self to induce immune response

A

Foreigness

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22
Q

It’s exist in unrelated plants/animals; either identical/closely related in structure

A

Heterophile antigen

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23
Q

It’s the most fatal (ex. Anaphylaxis/ Severe Asthma)

A

Type I Hypersensitivity Reaction

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24
Q

It’s the surface of antigens; ABO, Rh antigens

A

Glycoproteins

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25
Q

Least immunogenic; easily disintegrate in the circulation -> shorter circulation life

A

Nucleic Acids, Lipids and Amino Acids

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26
Q

It has constant amino acid sequence (constant region) allotype

A

Carboxyterminal

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27
Q

Capable of antigen binding even without the Fe but cannot agglutinate

A

Two fab fragments

28
Q

Responsible for the specific antibody

A

Variable region

29
Q

Fragment is crystalline; involved in the Ig biologic function

A

One Fc fragment

30
Q

Heavy chains are interconnected

A

Disulfide linkages

31
Q

With varying antibody specificity (variable region) Allotype

A

Aminoterminal

32
Q

Both light and heavy chains are hold together by:

A

Covalent disulfide bonds

33
Q

It’s also known as Immunoglobulins

A

Antibodies

34
Q

It’s responsible for cytotropic reaction involving WBC

A

CH3

35
Q

It’s connect with receptors in cell membrane

A

CH3,

36
Q

Binds with complement protein specifically C1Q

A

CH2

37
Q

Found between the CH1 and CH2; flexibility of the antibody

A

Hinge region

38
Q

Responsible for the light chain; either kappa or lambda

A

CL

39
Q

It enhances the phagocytosis by facilitating the linking/ cross bridging of the phagocytes and the data target antigens

A

Opsonin

40
Q

Only antibody with secretory component

A

IgA

41
Q

The control of antibody secretion/release in the circulation

A

Immunoregulation

42
Q

Only Ig that has specific receptor on mast cells

A

IgE

43
Q

It has a 21 to 23 days of life

A

IgG

44
Q

What is the molecular weight of IgM

A

900T

45
Q

It has 5 Domains

A

IgM and IgE

46
Q

It’s responsible for mucosal immunity

A

IgA

47
Q

It’s predominant antibody in primary immune response

A

IgM

48
Q

Their immune system is already weak

A

Geriatric patients

49
Q

An antibody titer that is increasing the logarithmically

A

Log

50
Q

Antibody titer degraded

A

Decline

51
Q

It occurs in four phases after exposure to an antigen

A

Primary response

52
Q

No antibody is detectable

A

Lag

53
Q

Antibody titer is stabilizes

A

Plateau

54
Q

Other name of secondary response

A

Anamnestic/memory response

55
Q

It helps the immune cells to determine self from nonself

A

Generic control of immune response

56
Q

Their immune system is different from adults and children

A

Neonatal

57
Q

It’s predominant Ig in secretions

A

Secretory Ig

58
Q

It binds the basophil and mast cells

A

Reagenic Ig

59
Q

It has 2-3 days of life

A

IgD and IgE

60
Q

Best agglutinating antibody

A

Fxn’s

61
Q

Antibody is transferred from mother to developing baby

A

Acquired natural passive immunity

62
Q

It’s damaging and harmful to the baby

A

HDFN

63
Q

It will not precipitate /agglutinate the antigens but can only bind the epitope of the antigens

A

Monovalent type

64
Q

It produces by B lymphocytes or plasma cells in response to antigen stimulation

A

Antibodies

65
Q

GOOD LUCK!!!♥️

A

IMMUNOLOGY & SEROLOGY (1 decks)

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