MSRA: SLE & APLS Flashcards

1
Q

What are the investigations in SLE?

A

Raised ESR, normal CRP
Complement C3 and C4
Anti-bodies: ANA, anti-dsDNA, anti-Smith

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2
Q

What are the causes of drug-induced lupus?

A

Hydralazine
Procainamide
Isoniazid
Phenytoin

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3
Q

What are the blood results in anti-phospholipid syndrome?

A

Prolonged APTT

Low platelets

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4
Q

Which antibodies are associated with drug induced lupus?

A

Anti-histone antibodies

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5
Q

What are the features of SLE?

A

Rash
Arthritis
Serositis
Haematology

Oral ulcers
Renal impairment

Photosensivity
ANA
Immunology
Neurology

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