MSK imaging Flashcards

1
Q

What is Computed Tomography?

A

Uses X-ray source & ionising radiation

Rotates around patient to acquire a volume of data which can be reconstructed as required

Attenuation in different structures in different ways similar to X-rays but uses ‘Hounsfield units’

Computer data processing / algorithms produces images in multiple planes / slice thicknesses

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2
Q

Computed Tomography-Benefits

A

Cross-sectional / multi-planar / 3d ability
such as coronal, sagittal and axial slices

Ability to remove overlying structures
Such as separating out superimposition

xcellent contrast resolution compared to plain film
Meaning that we can see more in terms of the soft tissues and organs

Very useful to assess trauma and bone tumours
Compared to X-rays higher sensitivity and specificity

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3
Q

Computed Tomography – Trauma

A

CT can be used to detect both the presence and extent of fractures (subtle/complex) e.g. spinal

Joints & Intra-articular abnormalities:
damage to articular cartilage
loose bodies / fracture fragments
associated soft tissue structures

Evaluation of spinal fractures in relation to spinal cord are almost 100% accurate

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4
Q

CT is particularly useful when looking at bone related tumors in particular……

A

Contrast resolution – ability to differentiate between tissue types

Extent of bone lesion- How far the lesion grows?

Look and identify presence of cortical interruption – tumour which breaks out of the bone is considered more aggressive

Helps to evaluate soft tissue structures and we can use contrast agents to help support this.

Evaluation of complex/ overlying structures

Can be used to guide intervention – biopsies and treatment e.g. thermal ablation (Heating it up to kill tumour

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5
Q

What are Benign tibial bone lesions?

A

The radiographic appearance;
ground glass appearance
higher density or attenuation
sclerotic bone lesions
white thickened appearance

The black area shows an osteoma a bone forming tumors which produces osteoid. CT allows use to see inside the bone (darker regions) which the tumor forms from and the outer areas are where the body reacts and lay down new bone.
Even though this tumor is benign, and not life-threatening patients will still find it very painful so will require certain pain killers such as aspirin and to treat this would require thermal ablation and needle biopsy.

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6
Q

Examples of tumours

A

Aggressive axial lesion of the spine

Osteochondroma

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7
Q

Aggressive axial lesion of the spine

A

Patient lies prone flat on stomach
One half the vertebrate is missing because this the tumor.
Thermal obliteration is taking place with the needle being inserted into the spine guided by CT

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8
Q

Osteochondroma

A

Benign lesion
Mushroom like appearance
Cartilage is present on the top hence the name osteochondroma ‘bone’ & ‘cartilage’ growth.
CT is better able to demonstrate the cartilage cap

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9
Q

In summary why CT?

A

Excellent contrast resolution-more detail

Multi-planar / 3d reconstruction e.g. pelvis

Considered the Gold standard when evaluating traumatic injuries / tumours

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10
Q

Why not CT?

A

Use of ionising radiation (relatively high dose to patient

Artefacts (movement, volume effect, metalwork)

Non-specific; unable to provide characterisation of tissues (tumour type

Metallic artefacts can cause starburst effects and distorts the image

Lack of soft tissue detail

Can’t ifferentiate between tissues.

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11
Q

Name 7 ways CT can be used and applied

A

Diagnosing: Diagnosing disease: A CT scan can help diagnose a number of conditions, including bone and muscle conditions, infections, blood clots, and tumors.

Staging: Staging cancer: A CT scan can help determine the stage of a cancer. Or even bowel cancer screening programs

Monitoring: Monitoring treatment: A CT scan can help monitor the effectiveness of treatments, such as cancer treatment.

Guilding: Guiding procedures: A CT scan can help guide procedures such as biopsies, surgery, and radiation therapy.

Detecting: Detecting recurrence: A CT scan can help detect if a tumor has returned.

Planning: Planning radiation therapy: A CT scan can help plan external-beam radiation therapy.

Screening: Screening for osteoporosis: A CT scan can help look for signs of bone loss in older adults..

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12
Q

Magnetic Resonance Imaging- description

A

Uses magnets and radiowaves to create a strong magnetic field when patients are placed inside it causes hydrogen particles in the body to align.

Different rf pulse sequences (eg SE, STIR, fat supression) which causes H particles to become excited, and these can be used to demonstrate different tissue types

Different signal intensities (brightness) according to tissue type e.g. areas in body with high levels of water give have a greater signal intensity.

T1 & T2 are MRI sequences that uses different times between magnetic pulses to create an image.

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13
Q

Differences in Intensity: MRI

A

T1-weighted

Uses short TE and TR times to create images where fat appears bright and water and fluids appear dark. T1-weighted images are used to show normal soft-tissue anatomy and fat.

T2-weighted

Uses longer TE and TR times to create images where fluid and abnormalities appear bright. T2-weighted images are used to show fluid, tumors, inflammation, and trauma.

T1 scan might be used to look for structural abnormalities in the brain, while a T2 scan might be used to look for fluid-related conditions.

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14
Q

Differences in T1 and T2 weighted tissues in MRI

A

T1
fat yellow bone marrow- high
cortical bone- low
fluid- intermediate
acute blood- intermediate
red bone marrow- low
tumours- intermediate/low
lipoma- high

t2
fat yellow bone marrow- intermediate
cortical bone- low
fluid - high
acute blood- high
red bone marrow- intermediate
tumours- High
lipoma- intermediate

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15
Q

The benefits of MRI?

A

Soft tissues
Image soft tissues: MRIs are particularly good at imaging soft tissues like muscles, ligaments, tendons, and the brain, spinal cord, and nerves.

Differentiating
Differentiate between tissues: MRIs can better differentiate between fat, water, muscle, and other soft tissues than CT scans.

Radiation
Avoid radiation: MRIs don’t use ionizing radiation like x-rays, making them a good choice when frequent imaging is needed.

Blood flow
Measure blood flow: MRIs can help measure blood flow.

Staging
Stage cancer: MRIs can help determine the size of a tumor and whether it has spread.

Treatment
Evaluate treatment: MRIs can help evaluate how well a treatment is working.

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16
Q

Why not MRI?

A

Time
The average scan takes between 30-60 minutes

Availability
Low availability requires booking and preparation

Cost
High cost.

Contraindication
metallic implants & claustrophobia

Information
No additional information in some conditions

Artefact
Movement artefacts

17
Q

How can MRI help determine what the lesion is made up of.

A

Deciding if something is benign or malignant.
Using the T1 and T2 weighted images looking at fat, fluid and blood.
Helps to determine whether the tumor has a blood supply - bone infarct (interrupted blood supply).
Benign tumors don’t have a blood supply. Malignant tumors do.

18
Q

What is ultrasound?

A

Uses sound waves sent from a transducer

These waves are partly reflected as an echo when they interact with structures in the body

Larger echoes display a brighter signal on the screen

Great for soft tissue structures

The echo are not strong enough pass through bone / gas

Traditionally used for deep soft tissue structures in the abdomen liver, kidney etc.

19
Q

Ultrasound: pros and cons

A

Balance between frequency and resolution (detail)

Higher frequency results in higher resolution (detail)

However, higher frequency results in lower penetration (loss of engergy)

Better resolution vs. low penetration

Obs/abo uses lower frequencies but compromise with the detail/resolution

20
Q

Ultrasound in MSK

A

Can produce high resolution images of soft tissue structures

Specifically for superficial structures

Highly detailed in real time

Ability to identify blood flow – doppler imaging

21
Q

Why Ultrasound?

A

Resolution

-Highest resolution can be used to use to determine whether a child will develop genetic condition e.g. spinal bifida, cleft palate, heart abnormalities 

- Doppler used to assess for blood flow. E.g. tumour with a blood flow would suggest a malignancy

Soft tissue visualisation

Cheap

‘Safe’ does not use ionising radiation

High resolution images

Readily accessible

Guided intervention

Patient interaction

Symmetry y

Physiology as well as anatomy

Easy to repeat

Guidance of injections

22
Q

Why Not Ultrasound?

A

Operator dependency

Cannot assess deep structures or deep to air / bone

Artefacts

Limited image storage

Dependent on patient body habitus

Bony / deep articular structures

Non-specific findings

Large areas / vague symptoms

Cannot assess deep structures or deep to air / bone

23
Q

Pathology- Inflammation/ infection:

A

tendinous
abcess
tenosynovitis
cellulitis / oedema
synovitis

24
Q

Pathology- Soft tissue masses:

A

benign
malignant
cysts / ganglions
nerve sheath
FB’s

25
What is Radionuclide bone scan?
Can be described as being either ‘transmission’ or ‘emission’ Radioactive isotope injected into patient vascular system Radioactive Isotope is attached to a pharmaceutical suitable to a particular type of tissue e.g. brain, kidney Chosen body part will be highlighted and emits gamma radiation using the radioactive isotope. Transmission you are transmitting energy into somebody and measuring it as it passes through. Nuclear medicine would be classed as emission imaging as the patient would be radioactive and radiation would be coming from inside the patient outwards Isotope is a type of element in the periodic that has the same number of protons but has different number of neutrons
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What is a Typical full body bone scan?
Anterior & Posterior Predominantly used to identify ‘Hot Spots’ These are areas of increased metabolic activity. Such as fractures, arthritis and tumors. Its most commonly used for looking at skeletal metastasis PT above likely has metastatic disease Osteosarcoma of the knee with the rest of the body demonstrating metastasis
27
What is Arthritic survey - (uncommon)?
Anterior posterior views Predominantly used to assess which joints are affected by arthritis. Not as widely used today The downside is that it doesn’t give you that much anatomical detail.
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What is SPECT- combination of nuclear medicine and CT?
Single-positron emitting computed tomography Hybrid imaging of RNI and CT to provide: metabolic processes anatomical detail Helps to localise and diagnose the abnormality Very useful in imaging tumours in complex anatomical structures like the spine and pelvis
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Why Radionuclide bone scans?
It can show an image of the entire skeleton or a focussed area relatively quickly Provides metabolic activity rather than anatomical detail. So, we are more concerned about where the lesions are rather than what it looks like. It helps to identify the presence of metastatic disease and where they are distributed inside the body rather than providing specific detail. Primarily for metastatic disease although has uses in trauma, metabolic diseases, and infection Very sensitive as opposed to X-rays where you need to lose around 50% of your bone density to see a lesion.
30
What are the limitations to radionuclide bone scan?
Doesn’t fully diagnose a patient – could be metastatic disease, arthritis, infection or even a tumor cannot be 100% sure. Gives poor anatomical resolution (detail) - just shows areas with increased amount of metabolic activity Relatively long scan times which can lead to movement artefact so not useful in Peads or patient that can’t lay still. Use of ionising radiation & patient is still radioactive even when they have finished the scan. Will have designated areas to sit and go toilet. Not suitable for detecting certain bone cancers e.g. multiple myeloma because it’s a type of blood cancer found in the bone marrow not outer regions
31
What is DEXA / DXA?
Generally, it is not used to look at an image but rather to take a measurement of density of a patient’s bone. There are two different energy X-ray beams that pass through the patient These are absorbed and detected at different signal intensities which are used to their calculate bone density Their bone density is compared to that of the 'normal population' to identify osteoporosis and predict fracture risk The main aim is to reduce the risk of fractures occurring to a patients with osteoporosis or those at risk
32
Dexa
Typically taken for hip / spine / forearm (rare) T-score – average comparison to a normal young adult who will likely have the maximum amount of bone mass/density Z-score – average comparison of a person with the same age & gender as the patient Anything lower than a score of 0 would be classed as osteogenic or osteoporotic.
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DEXA- uses
Main use is to measure bone density and assess for osteopenia or osteoporosis However, it can also be used to assess body mass index (BMI) Lateral vertebral assessment now being used to assess for compression fractures associated with osteoporosis
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Why Use DEXA?
Very low dosage - less than 1/10th of chest X-ray Simple & quick to operate procedure - takes around 1 minute Only test that can be used to diagnose osteoporosis due to the measurement of bone density and helps to assess for the risk of fractures Relatively widely available with relatively low costs associated with it
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Why Not Use DEXA?
Still does use ionising radiation Limited information- only gives a risk factor not a prognosis e.g. the chance of recovery or reoccurrence Limited anatomical detail – other than the lateral vertebral assessments Not suitable for spinal deformity, prosthesis or metalwork will not give you an accurate reading
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