MSK Flashcards

1
Q

Describe psoriatic arthritis

A

Chronic inflammatory arthropathy assoc w/ psoriasis that affects peripheral and axial joint and entheses (ligaments and tendons)

Gentetic susceptibility - HLA-B27 and HLA-Cw6

Affects 30-50 yrs

10% of psoriatic pop- appears at same time as skin disease

Predom peripheral arthritis of hands and feet

Sacroiliac involved in 20%

DIPs first affected assymetrically (pencil in cup deformity)

Histologically similar to RA but is not as severe, remissions are more frequent, and joint destruction less frequent

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