MS Flashcards
Relapsing-Remitting MS (RRMS)
There is a period of relapse and remission. The period between the two phases can be from days to years. As the disease progresses the remission can increase in disability as the myelin sheath does not have time to heal itself and will keep deteriorating.
Secondary progressive MS (SPMS)
Will follow RRMS after 10-20 years. Where the patient has not as many or no periods of remission. Neurological function is worsened.
CAN BE:
Active –> see changes in MRI
Non-Active –> see no changes in MRI
Progression –> gradually worsening symptoms
Non-Progression –> no change in symptoms
Primary Progressive MS (PPMS)
Worsening neurological function from the onset of symptoms with no periods of relapse or remission. (gradual and steady progression)
CAN BE:
Active –> see changes in MRI
Non-Active –> See no changes in MRI
Progression –> gradually worsening symptoms
Non-Progression –> no change in symptoms
–> Active relapse can occur where sudden changes are made but rare.
Clinically Isolated Syndrome
–> similar to MS
first episode of inflammatory demyelination in the CNS
- must last at least 24hrs
characteristics of MS but does not fit criteria
- If MRI changes more liekly to get MS –> 60-80%
10 Signs and Symptoms of MS
- Ataxia
- Speech Problems
- Dizziness
- Pain (neuropathic or MSK)
- Disturbed vision (optic nerve usually first affected)
- Spasticity
- Cognitive Difficulties
- Bladder control
- Fatigue
- Numbness
Management Strategies for MS
Repetitive task training
General Exercise
Falls prevention
–> pharmacological therapies have no recommendations and exercise and movement is a big factor in helping with symptoms.
Medication
Overall: corticosteroids, Plasma exchange
Beta interferons (RRMS)
Ocrelizumab (PPMS, RRMS)
Antispastic medication
