MRT isotopes Flashcards
Lu-177 Dotatate
Approved for clinical dosimetry, tradename Lutathera. For NET
Lu-177 PSMA
Approved for clinical dosimetry, Pluvicto tradename. For castrate resistant prostate CA.
I-131 NaI
Approved for clinical dosimetry, I-131 Sodium Iodide. For Thyroid CA.
I-131 MIBG
Approved for clinical dosimetry, Azedra tradename. For Neuroblastoma, pheochromocytoma + paraganglioma
Y-90
Not approved for clinical dosimetry. Kernel exists for research in MIM. For NETs
Ra-223-dichloride
Therapy is approved but as alpha emitter this is a research feature in MIM. Tradename Xofigo. For metastatic castration-resistant prostate cancer with bone mets but no visceral mets
Cu-67
Not approved for clinical dosimetry. Kernel exists for research in MIM. For NETs
Ac-225-PSMA
Not approved for clinical dosimetry. Kernel exists for research in MIM. For metastatic castrat- resistant prostate CA. Alpha Emitter
Ac-225-DOTATOC
Not approved for clinical dosimetry. Kernel exists for research in MIM. For NETs. Alpha emitter
Pb-212
Not approved for clinical dosimetry. Kernel exists for research in MIM. Delivers alpha particle radiation for PSMA or SSRT. Decays to alpha Bi-212.
Lu-177-DOTATOC
Approved for clinical dosimetry. For NETs
Ga-68-DOTATATE
PET tracer, Pre-Therapy planning for Lu177 Dotatate. Kernel available in MIM.
I-124
PET tracer, Pre-Therapy planning for I131 NaI. Kernel available in MIM.
Cu-64-DOTATATE
PET tracer, surrogate for Lu177 Dotatate or Pre- therapy planing for Cu67 Dotatate. Kernel available in MIM. Better planning tracer than G-68 due to the longer half life.
F-18-PSMA
PET tracer, Pre-therapy planning for PSMA. Kernel available in MIM.