MRI Flashcards
Spectroscopic study of the magnetic properties of nucleus of the atom
Nuclear magnetic resonance
Energy coupling that causes the individual nuclei, when placed in a strong external magnetic field, to selectively absorb and later release energy unique to those nuclei and their surrounding environment
Resonance
Fundamental property of matter; it is generated by moving charges, usually electrons
Magnetism
Magnetic properties of materials result from the
Organization and motion of the electrons in either a random or a nonrandom alignment of magnetic “domains” which are the smallest entities of magnetism
Origin of the magnetic field lines
North pole
Return of magnetic field lines
South pole
Can be conceptualized as the number of magnetic lines of force per unit area, which decreases roughly as the inverse square of the distance from the source
Magnetic field strength/magnetic flux density
Earth’s magnetic field is
0.05 mT
magnetic field strength and field density are dependent in the
Amplitude of current and number of coil turns
Magnetic field lines extending beyond the concentrated field are known as
Fringe fields
Performance criteria for magnet type
Field strength, temporal stability, field homogeneity
Characteristic of certain metals that when maintained at extremely low temperatures, exhibit no resistance to electric current
Superconductivity
Replenishment of the liquid helium must occur continuously, because if the temperature rises above a critical value, the loss of superconductivity will occur and resistance heating of wires will boil the helium, resulting in a
Quench
Common superconductive magnets have field strengths of
1.5 to 3 T
Magnetic field strength used for research application
4-7 T
Interact with the main magnetic field to improve homogeneity (minimal variation of the magnetic flux density) over the volume used for patient imaging
Shim coils
Exist within the main bore of the magnet to transmit energy to the patient as well as to receive returning signals
Radiofrequency coils
Contained within the main bore to produce linear variation if the magnetic field strength across the useful magnet volume
Gradient coils
Describes the extent to which a material becomes magnetized when placed in a magnetic field
Magnetic susceptibility
Have slightly negative susceptibility and oppose the applied magnetic field, because of paired electrons in the surrounding electron orbitals
Diamagnetic elements
calcium, water and most organic materials are examples of
Diamagnetic materials
With unpaired electrons, have slightly positive susceptibility and enhance the local magnetic field, but they have no measurable self magnetism
Paramagnetic materials
Molecular oxygen, deoxyhemoglobin, methemoglbin and gadolinium -based contrast agents are examples of
Paramagnetic materials
Superparamagnetic materials that augment the external magnetic field substantially. Exhibits self-magnetism
Ferromagnetic
Iron, cobalt and nickel are examples of
Ferromagnetic materials
Depleting magnetic materials
Diamagnetic
Augmenting magnetic materials
Paramagnetic materials
If there are equal number of protons and neutrons in the nucleus, the nuclear magnetic moment is
Essentially zero
If the number of protons and neutrons are unequal, the nuclear magnetic moment is
Generated
Principal focus for generating MR signals
Nucleus of hydrogen atom, the proton
Under the influence of an applied external magnetic field, the protons assume a nonrandom alignment in 2 possible orientations
Parallel and antiparallel
Between parallel and antiparallel directions, at equilibrium, a slight majority exists in the
Low energy parallel direction
Protons also experience a torque in a perpendicular direction from the applied magnetic field that causes
Precession
Precession occurs at what direction of frequency
Angular frequency
Describes the dependence between the magnetic field and the angular precessional frequency
Larmor equation
Two frames of reference in the applied magnetic field
Laboratory frame and rotating frame
Stationary reference frame from the observer’s point of view
Laboratory frame
A spinning axis system whereby the x-y axes rotate at an angular frequency equal to the Larmor frequency
Rotating frame
Slightly higher precessional frequency is observed as a slow ______ rotation
Clockwise rotation
Slightly lower precessional frequency is observed as a slow _______ rotation
Counterclockwise
Component of the magnetic moment parallel to the applied magnetic field
Longitudinal magnetization
Component of the magnetic moment perpendicular to x-y plane
Transverse magnetization
Corresponds to the energy separation between the protons in the parallel and antiparallel directions
Resonance frequency
Considers the RF energy as photons (quanta) instead of waves
Quantum mechanics model
Result of angular displacement of the longitudinal magnetisation vector from the equilibrium position
Flip angles
Term describing the release of energy back to lattice
Spin-lattice relaxation
T1 time is strongly dependent on the
Physical characteristics of the tissues and their associated hydration layers
Longer T1 relaxation time is taken from
Solid organs, unstructured tissues and fluids in bulk water
Shorter T1 relaxation time is achieved with
Structures and moderately sized proteins and fatty tissues
What influences T1 and T2 relaxation
Molecular motion, size and interactions
T1 values are _______ for higher field strength magnets while T2 values are unaffected
Longer
Period between B1 excitation pulses
Time of repetition (TR)
Time between excitation pulse and the appearance of the peak amplitude of an induced echo, which is determined by applying a 180 degree RF inversion pulse or gradient pplariry reversal at a time equal to TE/2
Time of echo
Time between an initial inversion/excitation (180 degrees) RF pulse that produces maximum tissue saturation and a 90-degree readout pulse
Time of inversion
Produced damped sinusoidal electronic signal from rotating at the Larmor frequency
Free induction decay
State of tissue magnetization from equilibrium conditions
Saturation
At equilibrium, the protons in a material are saturated or unsaturated?
Unsaturated
Occurs because the repetition time between excitation pulses does not allow for full return to equilibrium, therefore the Mz amplitude for the next RF pulse is reduced
Partial saturation
Describes the excitation of the magnetized protons in a sample with a 90 degree pulse converts Mz into Mzy and creates the largest phase coherent transverse magnetization that immediately begins to decay at a rate described by T2* relaxation
Spin echo
It is proportional to the difference in signal intensity between adjacent pixels in an image, corresponding to different voxels in the patient
Contrast
Sequence designed to produce contrast chiefly based on the T1 characteristic of tissues with de-emphasis of T2 and proton density contributions to the signal
T1-weighted SE sequence
Most intense signal in T1
Fat
Relies mainly on differences in the number of magnetized protons per unit volume of tissue
Proton density contrast weighting
Sequence that achieves the highest overall signal intensity and the largest signal to noise ratio; however, the image contrast is relatively low and therefore the contrast-to-noise ratio is not necessarily larger than achievable with T1 or T2 contrast weighting
Proton density weighting
Generated from the second echo produced by a second 180 degree pulse of a long TR spin echo pulse sequence, where the first echo is proton density weighted with short TE
T2 weighting
Emphasizes T1 relaxation times of the tissues by extending the amplitude of the longitudinal recovery by a factor of two
Inversion recovery
Delay between the excitation pulse and conversion to transverse magnetization of the recovered longitudinal magnetization
Inversion recovery
Pulse sequence that uses a very short T1 and magnitude signal processing, where Mz signal amplitude is always positive
Short tau inversion recovery
Reduces distracting fat signals and chemical shift artifacts
Short tau inversion recovery
Reduces CSF signal and other water-bound anatomy in the MR image by using a T1 selected at or near bounce point of CSF to permit better evaluation of the surrounding anatomy
Fluid attenuating inversion recovery
Downsides of spin echo and inversion recovery SE sequences
Less sensitive to magnetic field inhomogeneities, magnetic susceptibilities and generally gives high SNR and CNR, relatively long TR and corresponding long acquisition times
Uses a magnetic field gradient applied in one direction and then reversed to induce the formation of an echo, instead of 180 degree inverse pulse
Gradient echo
Not a true spin echo but a purposeful dephasing and rephasing of the FID
Gradient echo
Magnetic field inhomogeneities and tissue susceptibilities caused by paramagnetic or diamagnetic tissues or contrast agents are emphasized in
Gradient echo imaging
Magnetic field gradient induces the formation of an _____ Instead of 180-degree RF pulse
Echo
Transverse magnetization spins are ______ with an applied gradient of one polarity
Dephased
Transverse magnetization spins are _____ with the gradient reversed in polarity
Rephased
Transverse magnetization is higher/lower? For small flip angles compared to larger flip angles
Higher
A relatively long TE tends to emphasize the differences between
T2* and T2