MRI Flashcards

1
Q

What is MRI?

A

a spectroscopic imaging technique used in medical settings to produce images of the inside of the human body

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2
Q

How does MRI work?

A

absorption + emission of energy of the RF EM Spectrum

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3
Q

Adv of MRI (4)

A
  • Utilises non ionizing radition
  • ability to image in any plane
  • very low incidents of side effects
  • ability to diagnose, visualize + evaluate various illnesses
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4
Q

Components of MRI (4)

A
  • Magnet - powerful uniform magnetic field
  • Gradient magnet (lower in strength)
  • RF equipment
  • Powerful Computer
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5
Q

Field strength of MRI magnet

A

.5 - 2.0 T

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6
Q

Types of magnets used in MRI (4)

A
  • Resistive Magnets
  • Permanent Magnets
  • Super conducting magnets
  • Gradient Magnets (used to create variable field)
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7
Q

Proton and neutron spins are known as …

A

… nuclear spins

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8
Q

What is spin?

A

A small magneti field, either + or - and mathematical value of 1/2

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9
Q

An unpaired component has a spin of 1/2 and two particles …

A

… with opposite spis cancel out

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10
Q

In NMR, the magnetic field is produced by …

A

… the unpaired nuclear spins

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11
Q

Why are Protons important to MIR? (4)

A
  • +’ve charge
  • spin about central axis
  • a moving (spinning) charge creates a magnetic field
  • straight arrow (vector) indicates the direction of the magnetic field
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12
Q

When placed in a large magnetic field, hydrogen atoms have …

A

… a strong tendancy to align in the direction of the magnetic field

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13
Q

The magnetic field runs down the …

A

… centre of the tube, so the hydrogen protons will align at either the head or feet

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14
Q

Majority of protons will …

A

… cancel out, but the net number of protons is sufficient to produce an image

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15
Q

MRI machine applies a RF pulse that is …

A

… specific to hydrogen

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16
Q

RF pulse are applied through a coil that is …

A

… specific to the part of the body being scanned

17
Q

The gradient magnets are …

A

… rapidly turned on and off which alters the magnetic field

18
Q

Larmor Equation

19
Q

What does the Larmor Frequency?

A

Frequency need to excite transverse magnetization (precession)

20
Q

When the RF pulse is turned off, the hydrogen protons …

A

… slowly return to their natural alignment within the magnetic field and release their excess stored energy

21
Q

What happens to the released energy? (3)

A
  • Released as heat
  • Exchanged and absorbed by other protons
  • Released as Radio Waves
22
Q

Measuring the MR Signal (3)

A
  • Moving proton vector induces a signal in the RF antenna
  • Signal is picked up by coil and sent to computer
  • Computer uses Fourier transform to convert to an image
23
Q

Magnetisation State (2)

A

A

  • Protons spinning in nature, w/o external mag field.
  • Directions of spins are random and cancel out each other
  • Net magnetisation is 0

B

  • Large magnetic field, B_0, spins align themselves either
    • against (high energy state)
    • along (low energy state)
  • Slight abundance of spins aligned in low energy state
24
Q

Proton Alignment (4)

A

A - spin of a proton aligned to B0 in the z-axis

B - An external perturbing magnetic field, B1, knocks the vector out its axis, which is now aligned at a new angle w.r.t B0

C - As the pertubing field B1 is removed, the vector gradually starts returning back to its original state

D - begins to wobble

25
Resonance Eqn
v - resonant frequency gamma - gyromagnetic ratio B\_0 - magnetic field
26
T1 Parameter
the **spin-lattic** relaxation time-scale for the **longitudinal magnetisation** to come back to its original value
27
T2 Parameter
the **spin-spin** relxation time for the **transverse magnetisation** to come back to its initial value
28
T1 weighted imaging has ...
... higher spatial resolution
29
T2 weighted imaging has ...
.... higher tissue contrast
30
What does the image represent?
Every tissue layer has a different volume of water thus a different number of hydrogen atoms which produce different images based on the # hydrogen atoms