Moving Cargo in the cell

Question 1

What are the two types of motor proteins?

Answer 1

• actin based molecular motors (myosin family move along actin molecules)
• microtubule molecular motors

Question 2

How many domains does myosin contain?

Answer 2

3

Question 3

What is the difference between processive and non-processive motors

Answer 3

in non-processive motors the net movement of actin filament results from uncoordinated actin attachmpentand detachment of many myosin along the filament

in processive heads are working together which ensured that the cargo stays attached to the actin filament long enough to be transferred along it

Question 4

How is non muscle myosin II regulated?

Answer 4

both motor activity and thick filament assembly can be regulated by the action of kinases-myosin light chain kinase

Question 5

What is myosin important for in non-muscle cells?

Answer 5

cytokinesis
transport
cell locomotion
cytoplasmic streaming

Question 6

What are the two types of kinesics?

Answer 6

cytosolic (membrane bound vesicles and organelles are transported by their own specific kinesis along well defined routes in the cytosol)
spindle (spindle assembly and chromosome segregation during cell division. Often kinesis related proteins)

Question 7

Which end of the microtubule do conventional kinesins move towards?

Answer 7

postive

Question 8

What are the two types of dyneins?

Answer 8

cytosolic-movement of vesicles and chromosomes

axonemal-beating of cilia and flagella

Question 9

What end do dyneins move to of an MT?

Answer 9

negative end

Question 10

What is the fastest motor protein?

Answer 10

Dynein

Question 11

Are dyneins procressive or non-processive?

Answer 11

processive