Movement and other Flashcards
What does bromocriptine do?
Bromocriptine is an ergot derivative that stimulates dopanine D2 receptors. Non-ergot derivatives include ropinirole and pramiprexole.
Medications used to treat Parkinson’s aim to have what activity?
Increased dopamine action and/or decreased cholinergic affect.
What does haldol do?
Dopamine receptor antagonist.
-is used in movement disorders such as Huntington’s disease but has extraparametal and anti-cholinergic side effects. Side effects can mimic Parkinson’s symptoms.
What is Lhermitte’s sign in MS?
Electrical sensation that runs down the back and into the limbs (shoulders) it is elicited by bending the head forward (neck flexion).
This is caused by involvement of the posterior columns.
-There’s increased sensitivity of the Myelin to stretch or traction.
What is Uhthoff’s phenomenon?
T
What do these medications have in common?
Metoclopramide, lithium, haloperidol
Parkinson like features effects on the dopamine Neuro transmitter.
What is Charcot Triad?
Advanced stages of MS including scanning speech, intention tremor, and the nystagmus.
-Scanning speech is characterized as being explosive speech that is broken into syllables
Describe features of lewy body dementia.
Cerebellar impairment, including ataxia and dysarthria
-fluctuating course,
extrapyramedal features,
occasional visual hallucinations
multi system atrophy what are some features?
Autonomic involvement including orthostatic hypertension, thermoregulatory dysfunction, and impotence.
When would you expect to find Arnold-Chiari malformation type II?
Myelo-meningocele where the protruding sac contains meninges, spinal cord and spinal fluid there is associated Arnold – Chiari malformation which presents in approximately 80 to 90% of patients.
What causes locked in syndrome?
Lesion to ventral pons with and intact reticular activating system. Can be seen with bilateral basilar artery lesion.
Describe the Miller Fischer variant of guillan Baret syndrome.
Ophthalmoplegia, ataxia and areflexia
Only 5% of GBS cases event in this descending fashion as opposed to the conventional acsending paralysis.
What is the risk of too rapid correction of hyponatremia.
Central Pontine Myelinolysis
What does Endrophonium do?
Reversible acetylcholinesterase inhibitor for myasthenia gravis
A spinocerebellar degeneration disease.
- AutoSomal recessive
- absent deep tendon reflexes
- scoliosis
- nystagmus
- NO seizures
Freidricks ataxia
