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Neuroboards > Movement > Flashcards

Movement Flashcards

1
Q

Papez

A

MATCH mamillary, ant thal, cingulate, hippocampus

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2
Q

Ach

A

Meynert

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3
Q

Norad

A

Ceroulus

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4
Q

Serot

A

Raphe

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5
Q

Dopa

A

nigra pars compacta

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6
Q

GABA

A

accumbens, nigra pars reticulata

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7
Q

Friederichs

A

AR GAA repeat in frataxin ch9, neuropathy + UMN + cerebellar, high arch feet, spine deformity, cardiac (coQ10 analogue idebenone treats)

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8
Q

SCA

A

AD most, CAG repeat expansion, progressive truncal and limb ataxia, UMN/spasticity, MRI atrophy, SCA3 (+, ataxin 3 CAG, bulbar sx, dopa resp park), SCA7 (vision loss)

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9
Q

Fragile X-tremor-ataxia sx

A

CGG repeat FMR1, ataxia, parkinsonism (like MSA-C), retard grandson, T2 hyper inf cerebellar peduncles

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10
Q

Entacapone

A

COMT inh (inc dopa half life) [liver]

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11
Q

ropinirole, pramipexole

A

Dopa agonists (D2, D3), [impulse control, sedation]

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12
Q

rasagiline, selegiline

A

MAOB inh (dec dopa metab), insomnia

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13
Q

trihexyphenidyl, benztropine

A

Anticholinergics (for tremor only), cognitive

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14
Q

presenilin-1 and 2

A

(ch14 early aggressive) ch1 early

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15
Q

AD path

A

amyloid plaque (extracellular), neurofib tangles (intraneuronal tau), granulovacuolar degeneration, Hirano bodies (actin cytoplasm inclusion)

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16
Q

AD CSF

A

low amyloid, high tau and p-tau

17
Q

Huntington ch

A

ch4

18
Q

Dentatorubral-pallidoluysian atrophy

A

AD CAG repeat ch12, myoclonus, choreoathetosis

19
Q

Lesch-Nyhan

A

X HGPRT, hyperuricemia, kidney stones, psych, choreatetosis, self mutilation

20
Q

Dopa-responsive dystonia

A

GCH1 or tyrosine hydroxylase def

21
Q

Paroxysmal dyskinesias

A

kinesigenic (worse startle/hypervent, AED carbamazepine), nonkinesigenic (worse etoh/caf/fatigue), exertional (exercise, GLUT-1 mut high CSF gluc, keto)

22
Q

EA1

A

KCNA1 facial twitch, myokimia, AEDs

23
Q

EA2

A

CACN1A4 same as hemiplegic migraine, brainstem sx, acetazolomide, 4-aminopyridine

24
Q

Kluver Bucy

A

b/l ant temp/amygdala, hyperoral + sensitive to environment + blunted + hypersex + visual agnosia

25
Q

Pure word deafness

A

impaired auditory language comprehension, normal comprehension of reading (compared to wernickes), b/l sup temporal gyri (between Wernickes and Heschl’s auditory cortex)

26
Q

Gerstman

A

finger agnosia + r/l + acalculia + agraphia, dominant inf parietal (angular gyrus)

27
Q

Transcortical sensory

A

Wernickes with intact repetition, thalamic aphasia, watershed MCA-PCA dominant

28
Q

Transcortical motor

A

broca with intact repetition, watershed ACA-MCA, disconnect from broca to supl motor

29
Q

Aphemia (pure word mutism)

A

no fluency, impaired repetition, intact auditory comprehension, writing and reading, dominant frontal operculum above broca

Neuroboards (7 decks)

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