Mouth Microbiome

Question 1

what is a commensal microorganism

Answer 1

lives within/ on host but does not cause any apparent disease

Question 2

what are benefits of resident human microbiota

Answer 2

• competivtive exclusion of exogenous pathogens
• Antagonism of exogenous pathogen
• promotion of normal develpment of the immune system
• Promotion of normal humn cellular physiology and nutrition
• enhncment os epithelial barrier function
• enhncment of ccellular prolifiration and wound healing response
• disease follows bacterial in-balnce

Question 3

which groups of microorganisms inhabit the mouth

Answer 3

eukaryotes prokaryotes viruses prions

Question 4

what type of eukaryotes inhabit the mouth

Answer 4

fungi- yeast, candida albicans protozoa

Question 5

what type of prokaryotes inhabit the mouth

Answer 5

eubacteria

Question 6

which types of viruses infect the oral mucosa

Answer 6

HPV- human papilloma EBV- epstein barr HSV- herpes

Question 7

what surfaces in the mouth can microorganisms colonise

Answer 7

mucosal surfaces /teeth/ saliva/ Gingival cervical fluid/ tongue /cheeks,/lip,/palate

Question 8

FACTORS INFLUENCING COLONISATION AND SURVIVAL

Answer 8

Temperature Redox potential (Eh) / oxygen concentration pH Nutrients (endogenous, exogenous) Host defences Host genetics Host lifestyle

Question 9

The Mouth as a Microbial Habitat •

Answer 9

warm, moist, nutritious – extensive biofilm formation • innate & adaptive host responses • rich array of viruses, bacteria, fungi & protozoa • mouth selective • mouth is hostile