Motor System Flashcards

1
Q

What is the motor system?

A

Motor system is anything that activates a muscle
This is the motor neurone pathway: Brain -> Spinal cord -> Muscle
It must go through the spinal cord and not go to the muscle directly
The motor neurones will always be there at the end of the pathway

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2
Q

Describe the motor neurones?

A

The motor neurones control limb and body movements
Alpha motoneurones -> muscles
Each motor neurone is associated with muscle fibres form a motor unit

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3
Q

What are motor units?

A

Motor unit = motor neurone + innervated muscle fibre (every fibre it innervates)

They vary in size, amount of tension produced, speed of contraction, and degree of fatigability
They are found in the ventral horn of the spinal cord

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4
Q

What is the motor pool?

A

A motor pool = all individual motor neurons that innervate a single muscle

Each individual muscle fiber is innervated by only one motor neuron, but one motor neuron may innervate several muscle fibers

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5
Q

Where can motor neurones be located within the ventral horn?

A

Medially - these are motor neurones innervating axial musculature

Laterally - these are motor neurones innervating distal musculature

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6
Q

What is a neuromuscular junction?

A

Like a synapse

Allows the muscle to contract when threshold is exceeded as sufficient neurotransmitter is released

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7
Q

What does a neuromuscular junction include?

A

The postsynaptic membrane is muscular
The sarcolemma (membrane of muscles) can transmit an action potential along it
The sarcolemma have T-tubials (a large indent in the cell surface membrane which brings the action potential directly to the sarcoplasmic reticulum)

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8
Q

How is the pathway controlled?

A

Using a closed loop

If disturbance occurs, feedback can be sent to the controller (brain/spinal cord) and assessed in order to correct it

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9
Q

What are muscle spindles?

A

Muscle spindles are stretch receptors in a muscle that primarily detect changes in the length of the muscle - stretching of spindle is a measure of the degree of stretch of the muscle itself

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10
Q

Where are muscle spindles found?

A

Parallel to the extrafusal muscle fibres

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11
Q

What do muscle spindles enable?

A

Detects change in muscle length and rate of change
Contributes to proprioception i.e. detection of position and movement of body in space
Enables regulation of muscle contraction and precisely matches force generation to motor task

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12
Q

What are the types of muscle fibres?

A

Extrafusal fibres
They form the bulk of the muscle and generate muscle tension
They receive their motor innervation from alpha motor neurons

Intrafusal fibres
The spindles of these fibres have a sensory function and do not generate tension
They receive their motor innervation from gamma motor neurones
Gamma is the one we are trying to control

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13
Q

Describe the fibres when relaxed, off air and on air?

A

Relaxed - Spindle fibre sensitive to stretch of muscle
Off air - Muscle contracted, slackened spindle fibre not sensitive to stretch of muscle
On air - Muscle contracted, contracted spindle fibre sensitive to stretch of muscle

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14
Q

What is the sensory input to the motor neurones?

A

la afferent

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15
Q

What is the golgi tendon organ?

A

It is a mechanoreceptor that lies in series with muscle fibres
Detects changes in muscle tension, as when the muscle contracts the force acts directly on the tendon
When the muscle over stretches this is stretched
This is to prevent tearing as it will shut down this muscle at this point and initiate the activation of the antagonistic muscle

Innervated by Ib afferents

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16
Q

What are all the sensory inputs from muscles to the spinal cord?

A

Muscle spindle:
Primary afferent, group Ia (senses stretch and rate of change in stretch),
Secondary afferent, group II (stretch only)
Group III and above are finer than the two above (nociceptive from muscle)

Tendon organs:
Group Ib

17
Q

What are the types of reflex?

A

Monosynaptic reflex

Oligo/Polysynaptic reflex

18
Q

Describe the stretch reflex?

A

From la fibres

Excitatory and travels to flexors - monosynaptic

Inhibitory and travels to extensors - polysynaptic (via intermediate nerone within the spinal cord)

19
Q

Describe the golgi tendon reflex?

A

From lb fibres and both polysynaptic

Excitatory -> extensors
Inhibitory -> flexors
opposite of the stretch reflex in order to counter it

20
Q

What is recurrent inhibition?

A

Reduces the response/output of motor neurones, this is coordinated by Renshaw cells (inhibitory interneurones) found in the grey matter of the spinal cord

Tremors occur when recurrent inhibition is turned off

21
Q

What are central pattern generators?

A

Neuronal circuits

Flexion and extension is a cyclic activity, with an alternating pattern
The brain is not always needed and the spinal cord can do this through its circuits
But the brain is needed to direct the spinal cord, to achieve the end goal, the spinal cord is just the executer
The spinal cord can take care of errors but not change the overall plan/end goal

22
Q

Why is hierarchical organisation needed?

A

For stability
Losing a few motor neurones is fine but losing something higher up i.e. In the brain you may lose some function

However, due to parallel systems there are multiple ways a system can produce an output