Motor Practice, Learning, and Dopamine Prediction Mechanisms Flashcards

1
Q

What are the three dopamine-related aspects involved in practice and learning?

A

Liking, learning, and wanting.

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2
Q

What is the prediction error mechanism?

A

A system where dopamine neuron firing changes based on whether outcomes are better or worse than expected.

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3
Q

What happens when an outcome is better than predicted?

A

Dopamine neurons fire faster (↑ AP rate), reinforcing learning.

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4
Q

What happens when an outcome is worse than predicted?

A

Dopamine neuron firing decreases (↓ AP rate), signaling disappointment.

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5
Q

What happens when the brain accurately predicts an outcome?

A

Dopamine neuron firing remains steady at baseline (~5 AP/sec); no learning occurs.

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6
Q

How does the brain use prediction error to learn?

A

It updates expectations and focuses attention on what caused the unexpected outcome.

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7
Q

What is an example of a real-life dopamine prediction error?

A

Car starts when expected not to — dopamine spikes and brain takes note.

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8
Q

What part of the brain helps track patterns and make predictions?

A

The prefrontal cortex (PFC).

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9
Q

What happens when the brain is unable to form predictions?

A

It becomes hyper-focused on uncertain events (e.g., gambling, sports, superstitions).

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10
Q

What is the “power of maybe” in dopamine prediction?

A

Unpredictable outcomes increase dopamine activity due to lack of reliable predictions.

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11
Q

How does dopamine influence wanting behavior?

A

Repeated use of DA agonists rewires circuits to compulsively seek rewards.

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12
Q

What brain connection becomes stronger in addiction?

A

Between the orbital frontal cortex and the dorsal striatum.

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13
Q

What does the orbital frontal cortex do in motivated behavior?

A

Directs short-term reward-seeking behavior.

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14
Q

What is long-term potentiation (LTP)?

A

Strengthening of synaptic connections through repeated activity, making future firing more likely.

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15
Q

What is long-term depression (LTD)?

A

Weakening of synaptic connections — often seen in motor refinement.

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16
Q

How does practice improve motor memory?

A

Repeated actions reinforce motor programs via LTP in basal ganglia circuits.

17
Q

What part of the brain generates and stores motor programs?

A

The basal ganglia.

18
Q

Why does writing by hand improve memory retention over typing?

A

It uses a more unique motor program, enhancing learning via motor encoding.

19
Q

Why does drawing enhance memory even more than writing?

A

It creates the most unique motor patterns, strongly activating motor memory systems.

20
Q

What analogy explains why unique motor programs aid memory?

A

Like bike riding — you can’t verbalize every step, but your body remembers.