motor control part 2 Flashcards

1
Q

which basal ganglia circuit plays a major role in cognitive control of motor activity?

A

caudate circuit

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2
Q

which basal ganglia circuit plays a role in subconscious execution of learned patterns of movement

A

putamen circuit

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3
Q

which area acts as a comparator, comparing intention with actual motor performance and can effect the cerebellum via climbing fiber input?

A

inferior olivary nucleus

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4
Q

what are the major inhibitory cells in the cerebellar cortex?

A

purkinje cells

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5
Q

strong stimulation of 1 climbing fiber would elicit what response?

A

complex action potential of 1 or few purkinje cells

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6
Q

strong stimulation of 1 mossy fiber would elicit what response?

A

simple action potential of 100s of thousands of purkinje cells

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7
Q

spontaneous and continuous writhing movements would be associated with a lesion in which area?

A

globus pallidus

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8
Q

a patient presents with a resting tremor, lead pipe rigidity in the extremities. voluntary movements are accurate but slow, where is there likely to be a lesion?

A

basal ganglia- substantia nigra

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9
Q

what is the cerebellar hemispheric circuit?

A

cortico ponto cerebello rubro thalamo corticospinal

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10
Q

patient presents with ataxia, unable to perform rapid alternating movements and unable to check movements of right arm. where is lesion most likely?

A

right side of cerebellum

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11
Q

cerebellar lesions create what type of finding due to double crossing?

A

ipsilateral- rebound

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12
Q

what symptoms are seen with a cerebellar lesion?

A

disruption of coordination, limb and eye movements
impaired balance
decreased muscle tone

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13
Q

the ventral spinocerebellar tract gains access to the cerebellum primarily via which peduncle?

A

intermediate/ middle

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14
Q

what does the floculonodular lobe/ vestibulocerebellum do?

A

governs eye movement and body equilibrium

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15
Q

what does the spinocerebellum do?

A

initiates movement

influences descending motor systems

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16
Q

the cerebrocerebellum/ lateral zone does what?

A

planning and initiation of movement and extra motor prediction
mental rehearsal of complex motor actions
conscious assessment of movement errors

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17
Q

if you administer yohimbine (alpha 2 receptor blocker) and then stimulate the sympathetic nervous system, what effect do you expect on the amount of norepinephrine released?

18
Q

what inhibits norepinephrine release?

A

norepinephrine inhibits itself

19
Q

mass SNS discharge involves?

A
– Increase in arterial pressure
– decreased blood flow to inactive organs/tissues 
– increase rate of cellular metabolism
– increased blood glucose metabolism
– increased glycolysis in liver & muscle
– increased muscle strength
– increased mental activity
– increased rate of blood coagulation
20
Q

denervation supersensitivity is associated with what adaptations?

A

up regulation of receptors by target tissue

21
Q

what is the effect of the SNS stimulation on most vascular smooth muscle?

A

constriction

22
Q

the adrenal medulla is an extension of the?

A

SNS system

23
Q

SNS stimulation releases what hormones?

A

epinephrine and norepinephrine

24
Q

Stimulation of SNS to raise BP to maintain perfusion of CNS is called?

A

cushing reflex

25
what is ondines curse?
abnormal respiratory patterns
26
the myenteric plexus controls?
gut motility- can coordinate peristalsis in intestinal tract that has been removed from the body
27
myenteric plexus excitatory motor neurons release?
Ach | substance P
28
myenteric plexus inhibitory motor neurons release?
dynorphin | vasoactive intestinal peptide VIP
29
a patient presents with slight ptosis of the left eye, but the right pupil appears dilated compared to the left, they report that left side of face never sweats. thoughts?
interruption of the left sympathetic supply to the face
30
what is the condition with interruption of SNS supply to the head?
horners syndrome
31
in primary cultures of postganglionic SNS neurons, what inhibits release of norepinephrine?
GABA, adenosine, NPY, somatostatin, opiods, PGE, NO, dopamine
32
in primary cultures of postganglionic SNS neurons, what stimulates release of norepinephrine?
ACH, epinephrine, Ang II, corticotropin, PACAP
33
with parasympathetic postganglionic fibers, acetylcholine binds to what?
muscarinic receptor which effects a G protein
34
with SNS postganglionic fibers, norepinephrine binds to what?
alpha or beta receptor which effects a G protein
35
if there is a facilitated spinal segment at T6. what would you expect when 3 kg of pressure is applied to spinous process at T10 which is not in a state of segmental facilitation?
exaggerated response in adjacent paraspinal muscles only at T6
36
When pressure was applied to the spinous processes of normal vertebrae, up to 7 Kg of pressure, what response would be elicited?
minimal response in the adjacent paraspinal muscles
37
the CNS coordinates host defense activity T or F?
true
38
epinephrine has a greater affinity for alpha or beta?
beta
39
norepinephrine has a greater affinity for alpha or beta?
equal affinity for both
40
what are some symptoms of Horner's syndrome?
partial ptosis pupillary constriction anhydrosis enophthamos
41
what does the submucosal plexus regulate?
- ion and water transport across intestinal epithelium | - glandular secretion
42
the submucosal plexus communicates with what and releases what?
communicates with myenteric plexus | releases neuropeptides