Motor Flashcards
What is a myotome?
Muscle fibres innervated by a single spinal nerve
What is a motor unit?
A motor neuron and the extrafusal muscle fibres it innervates
What is the general function of the lateral corticospinal tract?
Motor supply to body
Speed, direction and agility of movements involved in rapid skilled fine movement
What is the general function of the rubrospinal tract?
Control of flexor muscle tone
What is the general function of the lateral vestibulospinal tract?
Control of extensor muscle tone
What is the general function of the ventral corticospinal tract?
Motor supply to body
How many spinal arteries are there?
2 posterior supply 1/3
1 anterior supply 2/3
What can be causes of infarction of spinal arteries?
Embolus Atheroma AAA Tumour Trauma
What are alpha motor neurons?
Innervate extrafusal muscle fibres
Large myelinated axons
What are gamma motor neurons?
Innervate intrafusal muscle fibres of the muscle spindle
Smaller diameter neurons
Which corticospinal tract decussates at the medullary pyramids?
Lateral corticospinal tract
The ventral tract decussates at the level of the lower motor neuron synapse
What does an upper motor neuron lesion cause?
Spastic paralysis
Hyper-reflexia
No muscle wasting or fasiculations
Extensor plantar response present
What symptoms does a lower motor neuron lesion cause?
Flaccid paralysis
Hypo-reflexia
Muscle wasting (atrophy)
Fasciculations
What is Babinski sign?
Normal adult response is digit plantarflexion - flexor plantar response
Extensor-plantar response occurs following upper motor neuron lesions
Great (big) toe extension & digit splaying
Present in newborn-2 years old and adults with UMN lesions
Corticospinal (pyramidal) tract lesions are associated with what signs and symptoms?
Loss of fine-skilled voluntary movements
Absent superficial abdominal reflexes
Cremasteric reflex absent
Clonus (rhythmic involuntary oscillation of a joint)
Extensor plantar response (Babinski)
Where can upper motor neuron symptoms occur?
Cortex Internal capsule Corona radiata Descending tracts Brainstem Spinal cord
Where can lower motor neuron lesions occur?
Spinal cord (at level of LMN cell body)
Spinal nerve
Cauda equina
Peripheral nerve damage e.g. radial nerve
What can cause motor neuron lesions?
Stroke Motor neuron disease Multiple sclerosis CNS Tumour Meningeal tumour Spinal tumour Trauma Penetrating injury Fracture Dislocation Stenosis IV disc prolapse
What symptoms will a spinal cord hemisection cause?
Upper and lower motor neuron signs in different parts of the body
LMN at level of injury, UMN below injury Ipsilateral
Brown-Sequard syndrome
Ipsilateral loss of fine touch and proprioception below
Contralateral loss of pain and temperature below
Describe cortical connections to cranial nerve motor brainstem nuclei
Bilateral supply from cortex
Innervation comes from corticobulbar/corticonuclear neurons
Main UMN innervation comes from contralateral cortex
MAIN EXCEPTION = Unilateral supply to CN VII to the lower face
What motor losses are associated with a brainstem lesion?
Ipsilateral face
Contralateral body
Describe the rubrospinal tract
From red nucleus in midbrain, decussates here
Descends contralaterally
Mainly to proximal upper limb & trunk muscles
Excite flexor LMN, Inhibit extensor LMN
Describe the vestibulospinal tract
Lateral vestibular nucleus in brainstem - pons/medulla border
Descends ipsilaterally
Antigravity (upright posture & balance)
Excites extensor LMN, Inhibits flexor LMN
What do reticulospinal tract neurons do?
Modulate lower motor neuron activity, locomotion and posture
Inhibit or excite lower motor neurons (α and γ)
Modulate sympathetic activity
Mostly originate from brainstem nuclei mesh
Fibres mostly run ipsilaterally
Modulate muscle activity/tone – especially in antigravity muscles
Control emotional movement of muscles of facial expression
Lesion to which tract results in spasticity seen in upper motor neuron lesions?
Reticulospinal tract, Net loss of lower motor neuron inhibition
Reticulospinal neurons excite inhibitory Renshaw cells to modulate muscle tone. Loss of the medullary reticular pathways in spinal cord injury contributes to spasticity and over-activity in α-motor neurons
Why can cervical cord damage lead to Horners syndrome?
Ventrolateral medullary nucleus helps control the sympathetic system Neurons in tract innervate preganglionic sympathetic fibres in lateral grey horn
What is Lou Gehrig’s disease?
Amyotrophic lateral sclerosis Degeneration of corticospinal tracts Degeneration of ventral horn Descending autonomic fibres interrupted Start in lower limbs, progresses to trunk & upper limbs
Describe the myotatic reflex
Passive muscle stretch sensed by muscle spindle
Reflex arc stimulates contraction of stretched muscle
Reflex arc inhibits antagonist muscle - reciprocal inhibition
Describe the inverse myotatic reflex
Golgi tendon organ detect stretch in tendons, initiate a protective reflex
1b afferent neurons carry sensation from tendon organ
Reflex arc inhibits agonist muscle and stimulates contraction of antagonist muscle
Describe the flexor withdrawal reflex
Withdrawal of a limb from a painful or noxious stimulus mediated by free nerve endings
Synaptic connections span several spinal cord levels
Stimulates ipsilateral flexors of limb
Inhibits ipsilateral extensors of limb
Describe the crossed extensor reflex
Ipsilateral flexor withdrawal and contralateral extensor activation
What are the supplementary and pre motor area for?
Motor pattern selection Generate intention to move Convert intention into movement Movement plan selection Area 4 words, Area 6 phrases/sentences
To move in an accurate meaningful we way require…?
Somatosensory inputs Visual inputs Proprioceptive inputs In order to create a mental body image Integrated in posterior parietal cortex (area 5,7) which receive extensive inputs from sensory cortex