MOS FINAL EP

Question 1

What triggers initial rise in feedback gain of renal blood volume/pressure control systems activated several hours after a severe hemorrhage?

Answer 1

Angiotensin II

Question 2

What is a principal sensory trigger for activation of tubuloglomerular feedback regulation?

Answer 2

Intracellular Cl- ions

Question 3

What would happen with a sudden blockage at venous end of capillaries in a healthy adult?

Answer 3

increase intracellular hydrostatic pressure

Question 4

What is the feedback gain of the baroreceptor blood pressure regulatory system if hemorrhage causes a drop in systolic blood pressure from 120 mmHg to 110 mmHg in the presence of regulation but 60 mmHg in its absence?

Answer 4

5

Question 5

What substance does not affect renal blood flow?

Answer 5

atrial

Question 6

What would not activate ANP synthesis?

Answer 6

Hemorrhage

Question 7

What would activate ANP synthesis (3 things)

Answer 7

high salt diet
high BP
vasoconstrictors

Question 8

what effect does angiotensin II have on efferent renal arterioles?

Answer 8

increases glomerular filtration rate

Question 9

Daily transmural diffusional water flux is around Xlitres/day?

Answer 9

80 000 litres

Question 10

What does arginine vasopressin do?

Answer 10

activates urea transport

Question 11

mannitol would likely be administered under conditions requiring??

Answer 11

decreased interstitial hydrostatic pressure

Question 12

What becomes more concentrated as kidney filtrates progress along the proximal convulated tubule of healthy human?

Answer 12

sodium bicarbonate

Question 13

What effect does increased skin temperature have?

Answer 13

reduces the set-point temperature for sweating

Question 14

fever-associated temperature crisis causes?

Answer 14

elevation of set-point for shivering

Question 15

Nutrient exchange across capillary wall membranes is largely driven by?

Answer 15

diffusion

Question 16

Which of the following cell types is involved with renal acid-base balance regulation?

Answer 16

Intercalated

Question 17

Oncotic pressure is higher in afferent versus efferent arterioles T/F?

Answer 17

FALSE

Question 18

If urine has 100 times greater concentration of NaH2PO than NA2HPO, its ph would be?

Answer 18

4.8

Question 19

neonatal heat generation mostly arises from activation of?

Answer 19

brown fat

Question 20

What is a volatile acid?

Answer 20

carbonic acid

Question 21

What would be elevated by inhibiting carbonic anhydrase in kidney filtrates

Answer 21

sodium bicarbonate

Question 22

Stimulating the temperature control centre of the hypothalamic pre-optic area does what?

Answer 22

activates sweating

Question 23

What response mechanism has the fastest initial rise in feedback gain following severe hemorrhage?

Answer 23

Baroreceptor