Morphology Flashcards
1
Q
How do benign lesions look macroscopically?
A
They grow in a confined local area and have a pushing outer margin
2
Q
How do malignant lesions look macroscopically?
A
They have an irregular outer margin and may show areas of necrosis and ulceration
3
Q
How do benign lesions look microscopically?
A
Their cells closely resemble the parent tissue. They can be said to be well differentiated
4
Q
How do malignant cells look macroscopically
A
They can range from well to poorly differentiated
Poorly differentiated cells have the following features:
Increased nuclear to cytoplasmic ratio
Increased nuclear size
Increased nuclear staining= hyperchromasia
More mitotic figures
Increased variation in size and shape of cells and nuclei= pleomorphism
