Morphologic Abnormalities Flashcards
Anisocytosis
Variation in size
Equivalent to red cell distribution width RDW
Acanthocyte (spur cell)
Irregularly spiculated
Hemangiosarcoma
Liver disease
DIC
Autoagglutination
Clumping of RBC (does not disperse with saline- not rouleaux)
IMHA
Echinocytes (burr cell)
Regularly spiculed cells
Artefact
Glomerulonephritis
Pyruvate kinase deficiency
Elliptocyte
Oval or elongate RBC
Hereditary disorder
Ghost RBC
Lysed RBC
Haemolytic anaemia (usually immune)
Heinz bodies
Red inclusions in RBC
Oxidative injury - lymphoma,
DM, hyperthyroidism
Anticoagulant rodenticide, propylene glycol
Howell-Jolly bodies
Nuclear remnant
Regeneration Dyserythropoetic syndromes (hyposplenism)
Hypochromasia
Less hemoglobin
Iron deficiency
Physiologic in very young animals
Macrocytosis
Bigger RBC
Regeneration
Poodles
FeLV
Microcytosis
Smaller RBC
Iron deficiency
Akita, Shar Pei, Shiba inu
PSS
Poikilocytosis
Very variable RBC shapes, cannot be quantified
Regeneration
Iron deficiency
Polychromasia
Purple RBC (immature-abundant RNA)
Regeneration
Rouleaux formation
Stacking of RBC
Inflammation or neoplasia
Disperses with saline
Schistocytes
RBC fragments
Microangiopathy
Hemanhiosarcoma
DIC
