Morphogens Flashcards
1
Q
What is a morphogen
A
Soluble secreted molecule that acts at a distance to specify fates (more than one)
2
Q
What does pemissive mean/imply ?
A
Cell contains cell fate determinants and just needs a go signal
3
Q
What type of diffusion does the morphogen undergo
A
Restrictive
4
Q
What does HSP do
A
Binds ligands and reg diffusion / sequester or facilitates it
5
Q
Planar transcytosis
A
Repeated cycles of endocytosis and resecretion
6
Q
Trans read-out model
A
fate depends on amount of TF received
