More important cards 2 memorize Flashcards
1
Q
What disease do antibodies to hemidesmosomes cause?
A
Bullous pemphigoid
2
Q
What disease do antibodies to desmosomes cause?
A
Pelphigoid vulgaris
3
Q
What disease does congenital defects in keratin filaments 4 and 15 cause?
A
Epidermilysis bullosa simplex
4
Q
Genetic defects in Collagen VII cause Dystrophic Epidermolysis Bullosa
A
Dystrophic epidermolysis bullosa
5
Q
Genetic defects in Laminin-5
A
Junctional EB
6
Q
Role of fillagrin
A
Filaggrin cross-links
keratin tonofilaments and is important in the barrier function of the skin.
Filaggrin is
mutated in dry skin conditions including ichthyosis and atopic dermatitis
