more about biology Flashcards

1
Q

Metabolism

A

all chemical reactions occurring in an organism

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2
Q

Anabolism

A

chemical reactions that expend energy to make new chemical bonds

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3
Q

Catabolism

A

chemical reactions that harvest energy when bonds are broken

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4
Q

cofactors

A

usually metal ions, found in the active site participating in catalysis

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5
Q

coenzymes

A

nonprotein organic molecules, often used as an electron donor or acceptor in a redox reaction

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6
Q

Energy

A

the capacity to do work

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7
Q

kinetic energy

A

the energy of motion

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8
Q

potential energy

A

stored energy

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9
Q

Energy can take many forms

A

mechanical electric current

heat light

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10
Q

Heat energy is measured in

A

kilocalories.

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11
Q

One calorie

A

= the amount of heat required to raise the temp of water by 1oC

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12
Q

oxidation:

A

loss of electrons

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13
Q

reduction

A

gain of electrons

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14
Q

redox reactions

A

are coupled to each other

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15
Q

NAD+

A
  • is an electron carrier
  • NAD accepts 2 electrons and 1 proton to become NADH
  • the reaction is reversible
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16
Q

aerobic respiration

A

final electron receptor is oxygen (O2)

17
Q

anaerobic respiration

A

final electron acceptor is an inorganic molecule (not O2)

18
Q

fermentation

A

final electron acceptor is an organic molecule

19
Q

substrate-level phosphorylation

A

transferring a phosphate directly to ADP from another molecule

20
Q

oxidative phosphorylation

A

use of ATP synthase and energy derived from a proton (H+) gradient to make ATP

21
Q

The complete oxidation of glucose proceeds in stages

A
  1. glycolysis
  2. pyruvate oxidation
  3. Krebs cycle
  4. electron transport chain & chemiosmosis
22
Q

Glycolysis

A

converts glucose to pyruvate.

  • a 10-step biochemical pathway
  • occurs in the cytoplasm
  • 2 molecules of pyruvate are formed
  • net production of 2 ATP molecules by substrate-level phosphorylation
  • 2 NADH produced by the reduction of NAD+
23
Q

For glycolysis to continue, NADH must be recycled to NAD+ by either:

A
  1. aerobic respiration – occurs when oxygen is available as the final electron acceptor
  2. fermentation – occurs when oxygen is not available; an organic molecule is the final electron acceptor
24
Q

Pyruvate Oxidation

A

In the presence of oxygen, pyruvate is oxidized.

  • occurs in the mitochondria in eukaryotes
  • occurs at the plasma membrane in prokaryotes
  • in mitochondria, a multienzyme complex called pyruvate dehydrogenase catalyzes the reaction
25
Krebs cycle
oxidizes the acetyl group from pyruvate. -occurs in the matrix of the mitochondria -biochemical pathway of 9 steps -first step: acetyl group + oxaloacetate citrate (2 carbons) (4 carbons) (6 carbons)
26
The remaining steps of the Krebs cycle
- release 2 molecules of CO2 - reduce 3 NAD+ to 3 NADH - reduce 1 FAD (electron carrier) to FADH2 - produce 1 ATP - regenerate oxaloacetate
27
After glycolysis, pyruvate oxidation, and the Krebs cycle, glucose has been oxidized to
- 6 CO2 - 4 ATP - 10 NADH - 2 FADH2
28
electron transport chain (ETC)
is a series of membrane-bound electron carriers. - embedded in the mitochondrial inner membrane - electrons from NADH and FADH2 are transferred to complexes of the ETC - each complex transfers the electrons to the next complex in the chain
29
Electron Transport Chain
The higher negative charge in the matrix attracts the protons (H+) back from the intermembrane space to the matrix. The accumulation of protons in the intermembrane space drives protons into the matrix via diffusion.
30
Most protons move back to the matrix through
ATP synthase
31
ATP synthase
is a membrane-bound enzyme that uses the energy of the proton gradient to synthesize ATP from ADP + Pi.
32
Chloroplasts
organelles present in cells of plants and some other eukaryotes - contain chlorophyll for photosynthesis - surrounded by 2 membranes
33
thylakoids
are membranous sacs within the inner membrane
34
grana
are stacks of thylakoids
35
Mitochondria and chloroplasts:
- have 2 membranes - possess DNA and ribosomes - are about the size of a prokaryotic cell - divide by a process similar to bacteria